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001-es BibID:
BIBFORM117705
035-os BibID:
(Scopus)85180178281 (wos)001128612100001
Első szerző:
Solymossi Balázs
Cím:
Incidence and predictors of heart failure with improved ejection fraction category in a HFrEF patient population / Solymossi Balázs, Muk Balázs, Sepp Róbert, Habon Tamás, Borbély Attila, Heltai Krisztina, Majoros Zsuzsanna, Járai Zoltán, Vágány Dénes, Szatmári Ákos, Sziliczei Erzsébet, Bánfi-Bacsárdi Fanni, Nyolczas Noémi
Dátum:
2024
ISSN:
2055-5822
Megjegyzések:
Aims: The aim of the study was to assess the incidence and predictive factors of the development of heart failure with improved ejection fraction (HFimpEF) category during a 1 year follow-up period in a heart failure with reduced ejection fraction (HFrEF) patient population managed in a heart failure outpatient clinic. Methods and results: The study evaluated data from patients enrolled in the Hungarian Heart Failure Registry (HHFR). The incidence and predictive factors of the development of the HFimpEF category after 1 year follow-up were assessed in the group of patients who had HFrEF at baseline. We evaluated the incidence and predictors of the development of HFimpEF after a 1 year follow-up in relation to time since diagnosis of HFrEF in patients diagnosed within 3 months, between 3 months and 1 year, and beyond 1 year. The predictive factors of the development of HFimpEF were analysed using univariate and multivariate logistic regression analysis. Of the 833 HFrEF patients enrolled in the HHFR, the development of HFimpEF was observed in 162 patients (19.5%) during 1 year follow-up. In the whole patient population, independent predictors of the development of HFimpEF were female gender [odds ratio (OR): 1.73; 95% confidence interval (CI): 1.01?2.96; P < 0.05], non-ischaemic aetiology (OR: 1.95; 95% CI: 1.15?3.30; P < 0.05), and left ventricular end-diastolic diameter (LVEDD) <60 mm (OR: 2.04; 95% CI: 1.18?3.51; P < 0.05). The 1 year incidence of HFimpEF decreased in relation to time since diagnosis of HFrEF. The incidence of HFimpEF was 27.1% in patients diagnosed within 3 months, 18.4% in patients diagnosed between 3 months and 1 year, and 12.2% in patients diagnosed beyond 1 year. Non-ischaemic aetiology (OR: 4.76; 95% CI: 1.83?12.4; P < 0.01) and QRS width (OR: 0.81; 95% CI: 0.71?0.94; P < 0.01) for patients diagnosed within 3 months, LVEDD (OR: 0.54; 95% CI: 0.32?0.90; P < 0.05) and left atrial diameter ?45 mm (OR: 5.44; 95% CI: 1.45?20.4; P < 0.05) for patients diagnosed between 3 months and 1 year, and LVEDD < 67 mm (OR: 2.71; 95% CI: 1.07?6.88; P < 0.05) for patients diagnosed beyond 1 year were found to be independent predictive factors. Conclusions: In our study, in this HFrEF patient population managed in a heart failure outpatient clinic, the 1 year incidence of HFimpEF was found to be ~20%. The 1 year incidence of HFimpEF decreased in relation to time since diagnosis of HFrEF. The most important predictors of the development of HFimpEF were female sex, non-ischaemic aetiology, narrower QRS width, and smaller diameter of the left ventricle and left atrium.
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Heart failure with improved ejection fraction
Incidence
Predictive factors
Reverse remodelling
Megjelenés:
ESC heart failure. - 11 : 2 (2024), p. 783-794. -
További szerzők:
Muk Balázs
Sepp Róbert
Habon Tamás
Borbély Attila (1978-) (kardiológus)
Heltai Krisztina
Majoros Zsuzsanna
Járai Zoltán
Vágány Dénes
Szatmári Ákos
Sziliczei Erzsébet
Bánfi-Bacsárdi Fanni
Nyolczas Noémi
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