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001-es BibID:	BIBFORM016772
Első szerző:	Juhász Mária (belgyógyász)
Cím:	Gender-related differences in adolescent hypertension and in target organ effects / Juhász Mária, Katona Éva, Settakis Georgios, Paragh György, Molnár Csilla, Fülesdi Béla, Páll Dénes
Dátum:	2010
ISSN:	1540-9996
Megjegyzések:	To assess whether a gender difference exists in adolescent hypertension and its target organ damage and to compare potential confounding factors and target organ damage in hypertensive and normotensive adolescent girls. METHODS: From the Debrecen Hypertension Study, the anthropometric, blood pressure, and laboratory data as well as intima-media thickness (IMT) and left ventricular mass index (LVMI) of 58 hypertensive boys, 56 hypertensive girls, and 30 normotensive girls were analyzed. RESULTS: Both systolic and mean blood pressure values were higher in adolescent hypertensive boys than in girls. This difference was also present when comparing 24-hour average blood pressure values. Plasma concentrations of nitric oxide (NO) and endothelin-1 were not different in the two gender groups. IMT of the carotid arteries were similar in hypertensive boys and girls, but a significantly higher LVMI was detected in boys. A significant difference was detected in anthropometric data (height, weight, and body mass index [BMI]), plasma concentration of NO (lower levels in hypertensives), and IMT in hypertensive and normotensive girls (higher IMT in hypertensive girls). CONCLUSIONS: There is a difference between the severity of hypertension between hypertensive adolescent girls and boys. Hypertensive girls differ from normotensive girls not only in blood pressure values but also in risk factors and subclinical target organ effects. Further studies are needed to explain the gender differences in adolescent hypertension. The potential role of sex hormones in hypertensive teenagers also needs to be clarified in future works.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Journal of Women's Health. - 19 : 4 (2010), p. 759-765. -
További szerzők:	Katona Éva (1967-) (belgyógyász, diabetológus) Settakis, George Paragh György (1953-) (belgyógyász) Molnár Csilla (1962-) (aneszteziológus) Fülesdi Béla (1961-) (aneszteziológus) Páll Dénes (1967-) (belgyógyász, kardiológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM016773
Első szerző:	Páll Dénes (belgyógyász, kardiológus)
Cím:	Assessment of target-organ damage in adolescent white-coat and sustained hypertensives / Páll Dénes, Juhász Mária, Lengyel Szabolcs, Molnár Csilla, Paragh György, Fülesdi Béla, Katona Éva
Dátum:	2010
ISSN:	0263-6352
Megjegyzések:	The aim of the present study was to assess whether a difference exists between intima-media thickness and the left ventricular mass index in healthy nonhypertensive, white-coat hypertensive and sustained hypertensive adolescents. PATIENTS AND METHODS: Fifty-nine normotensive and 120 hypertensive adolescents were enrolled in our study. Hypertensive patients were classified into white-coat hypertension (WCH) and sustained hypertension groups based on 24-h ambulatory blood pressure measurements. Both normotensive and hypertensive individuals underwent routine laboratory tests, intima-media thickness measurements on the common carotid arteries and transthoracic echocardiography to measure the left ventricular mass index (LVMI). RESULTS: Intima-media thickness was higher both in WCH and sustained hypertension compared with healthy normotensive individuals (controls: 0.048 ± 0.01 cm, WCH: 0.056 ± 0.01 cm, sustained hypertension: 0.054 ± 0.012 cm, both P < 0.001 compared with controls, nonsignificant difference between the two hypertensive groups). There was no difference between the LVMI of control individuals and WCH (LVMI: 35.5 ± 10.3 g/m and 37.7 ± 11.2 g/m respectively, P = 0.87). LVMI in sustained hypertension group (LVMI: 44.1 ± 14.1 g/m) was significantly higher both compared with WCH (P < 0.05), and healthy adolescents (P < 0.001). CONCLUSION: Target-organ damage develops in a stepwise fashion in adolescent hypertension. An increased intima-media thickness can be demonstrated not only in the sustained but also in the white-coat form of adolescent hypertension.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Journal Of Hypertension. - 28 : 10 (2010), p. 2139-2144. -
További szerzők:	Juhász Mária (1975-) (belgyógyász) Lengyel Szabolcs (1981-) (belgyógyász) Molnár Csilla (1962-) (aneszteziológus) Paragh György (1953-) (belgyógyász) Fülesdi Béla (1961-) (aneszteziológus) Katona Éva (1967-) (belgyógyász, diabetológus)
Internet cím:	Szerző által megadott URL Intézményi repozitóriumban (DEA) tárolt változat DOI
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