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001-es BibID:BIBFORM053931
Első szerző:Végh Tamás (aneszteziológus, intenzív terápiás szakorvos)
Cím:Clinical observations on reversal of rocuronium-induced residual neuromuscular blockade by sugammadex after thoracic surgery / Tamás Végh, Marianna Juhász, István László, Attila Vaskó, Edömér Tassonyi, Béla Fülesdi
Dátum:2014
Megjegyzések:Objective: After thoracic surgery, a complete reversal of neuromuscular blockade (NMB) facilitatesventilatory movements and expectoration and enhances the possibility of early physiotherapy. Therefore,the aim of the present study was to evaluate the clinical usefulness of sugammadex for reversal of NMBafter anaesthesia for thoracic surgery.Design: prospective case series.Setting: university hospital.Participants: 49 patients undergoing thoracic surgical procedures (25 thoracotomies, 11 video-assistedthoracoscopies and 13 mediastinosciopies) were included.Interventions: Rocuronium was used for intubation and maintenance of NMB under continuousmonitoring with TOF Watch SX acceleromyograph. Residual NMB at the end of surgery was reversed byadministration of sugammadex 2 mg/kg BW.Main results: All patients had a residual curarisation at the end of surgery (TOF: 27.02 ? 25.9%).Time to 100% TOF recovery after sugammadex averaged 2.46 ? 0.58 minutes. Thirty three out of 49patients had mild hypothermia at the end of surgery. There was no difference in time needed for TOFrecovery to 100% between hypothermic and normothermic patients (hypothermic: 2.46 ? 2.9 minutes,normothermic: 1.81 ? 0.76 minutes, p = 0.29). Postoperative shivering occurred in 67% of the patients.Conclusions: We conclude that sugammadex allows fast and complete recovery of the neuromuscularfunction after thoracic surgical procedures even if mild hypothermia was present.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
thoracic anaesthesia
sugammadex
rocuronium
residual curarisation
Megjelenés:Romanian Journal of Anaesthesia and Intensive Care. - 21 : 1 (2014), p. 7-11. -
További szerzők:Juhász Marianna (1975-) (aneszteziológus) László István (1978-) (aneszteziológus) Vaskó Attila (1976-) (tüdőgyógyász) Tassonyi Edömér (1940-2022) (aneszteziológus) Fülesdi Béla (1961-) (aneszteziológus)
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001-es BibID:BIBFORM042442
Első szerző:Végh Tamás (aneszteziológus, intenzív terápiás szakorvos)
Cím:One-lung ventilation does not result in cerebral desaturation during application of lung protective strategy if normocapnia is maintained / T. Végh, Sz. Szatmári, M. Juhász, I. László, A. Vaskó, I. Takács, L. Szegedi, B. Fülesdi
Dátum:2013
ISSN:0231-424X 1588-2683
Megjegyzések:Background: Previously a report has suggested that administration of lung protective strategy for one-lung ventilation (OLV) results in oxygen desaturation of the brain parenchyma. The aim of our work was to confirm that the maintenance of normocapnia during protective OLV strategy results in alteration of cerebral blood flow and cerebral oxygen saturation as compared to double-lung ventilation. Methods: Data were obtained from 24 patients undergoing thoracic surgery. Cerebral oxygen saturation (rSO2) was continuously monitored by INVOS 5100C Cerebral Oxymeter System along with measurement of cerebral blood flow velocity (MCAV) by transcranial Doppler sonography. Arterial blood samples were taken for blood gas analysis in the awake state, in the supine and lateral decubitus position during double-lung ventilation (DLV), and during OLV. Results: When ventilation was changed from DLV to OLV, no significant change was observed in rSO2. A significant decrease of rSO2was found compared to the value observed during DLV in lateral decubitus at the time point 60 minutes after the start of OLV. No clinically significant changes in the MCAV was observed throughout the course of the thoracic surgical procedure. Conclusions: OLV does not result in clinically relevant decreases in cerebral blood flow and cerebral oxygen saturation during application of lung protective ventilation if normocapnia is maintained.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény hazai lapban
one-lung ventilation
cerebral oxygen saturation
thoracic anesthesia
lung protective ventilation
Megjelenés:Acta Physiologica Hungarica 100 : 2 (2013), p. 163-172. -
További szerzők:Szatmári Szilárd (1984-) (aneszteziológus) Juhász Marianna (1975-) (aneszteziológus) László István (1978-) (aneszteziológus) Vaskó Attila (1976-) (tüdőgyógyász) Takács István (1963-) (sebész) Szegedi László (aneszteziológus) Fülesdi Béla (1961-) (aneszteziológus)
Internet cím:DOI
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