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001-es BibID:	BIBFORM084100
Első szerző:	Kyrou, Ioannis
Cím:	Sociodemographic and lifestyle-related risk factors for identifying vulnerable groups for type 2 diabetes : a narrative review with emphasis on data from Europe / Kyrou Ioannis, Tsigos Constantine, Mavrogianni Christina, Cardon Greet, Van Stappen Vicky, Latomme Julie, Kivelä Jemina, Wikström Katja, Tsochev Kaloyan, Nanasi Anna, Semanova Csilla, Mateo-Gallego Rocío, Lamiquiz-Moneo Itziar, Dafoulas George, Timpel Patrick, Schwarz Peter E. H., Iotova Violeta, Tankova Tsvetalina, Makrilakis Konstantinos, Manios Yannis, Feel4Diabetes-Study Group
Dátum:	2020
ISSN:	1472-6823
Megjegyzések:	Abstract Background: Type 2 diabetes mellitus (T2DM) comprises the vast majority of all diabetes cases in adults, with alarmingly increasing prevalence over the past few decades worldwide. A particularly heavy healthcare burden of diabetes is noted in Europe, where 8.8% of the population aged 20?79 years is estimated to have diabetes according to the International Diabetes Federation. Multiple risk factors are implicated in the pathogenesis of T2DM with complex underlying interplay and intricate gene-environment interactions. Thus, intense research has been focused on studying the role of T2DM risk factors and on identifying vulnerable groups for T2DM in the general population which can then be targeted for prevention interventions. Methods: For this narrative review, we conducted a comprehensive search of the existing literature on T2DM risk factors, focusing on studies in adult cohorts from European countries which were published in English after January 2000. Results: Multiple lifestyle-related and sociodemographic factors were identified as related to high T2DM risk, including age, ethnicity, family history, low socioeconomic status, obesity, metabolic syndrome and each of its components, as well as certain unhealthy lifestyle behaviors. As Europe has an increasingly aging population, multiple migrant and ethnic minority groups and significant socioeconomic diversity both within and across different countries, this review focuses not only on modifiable T2DM risk factors, but also on the impact of pertinent demographic and socioeconomic factors. Conclusion: In addition to other T2DM risk factors, low socioeconomic status can significantly increase the risk for prediabetes and T2DM, but is often overlooked. In multinational and multicultural regions such as Europe, a holistic approach, which will take into account both traditional and socioeconomic/socioecological factors, is becoming increasingly crucial in order to implement multidimensional public health programs and integrated community-based interventions for effective T2DM prevention.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Diet Ethnicity Lifestyle Obesity Risk factors Socioeconomic status Type 2 diabetes
Megjelenés:	BMC Endocrine Disorders. - 20 : Suppl. 1 (2020), p. 1-13. -
További szerzők:	Tsigos, Constantine Mavrogianni, Christina Cardon, Greet Van Stappen, Vicky Latomme, Julie Kivelä, Jemina Wikström, Katja Tsochev, Kaloyan Nánási Anna (1995-) (háziorvos) Semánová Csilla (1991-) (PhD hallgató) Mateo-Gallego, Rocío Lamiquiz-Moneo, Itziar Dafoulas, George Timpel, Patrick Schwarz, Peter E. H. Iotova, Violeta Tankova, Tsvetalina Makrilakis, Konstantinos Manios, Yannis Kolozsvári László Róbert (1977-) (háziorvos) Rurik Imre (1953-) (háziorvos, foglalkozás-egészségügyi szakorvos, urológus) Jancsó Zoltán (1973-) (orvos, háziorvos szakorvos, foglalkozás-orvostan szakorvos) Ungvári Tímea Feel4Diabetes-Study Group
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001-es BibID:	BIBFORM084099
Első szerző:	Manios, Yannis
Cím:	Two-stage, school and community-based population screening successfully identifies individuals and families at high-risk for type 2 diabetes : the Feel4Diabetes-study / Yannis Manios, Christina Mavrogianni, Christina-Paulina Lambrinou, Greet Cardon, Jaana Lindström, Violeta Iotova, Tsvetalina Tankova, Fernando Civeira, Jemina Kivelä, Zoltán Jancsó, Samyah Shadid, Kaloyan Tsochev, Rocío Mateo-Gallego, Sándorné Radó, George Dafoulas, Konstantinos Makrilakis, Odysseas Androutsos, Kolozsvári László, Feel4Diabetes-study group
Dátum:	2020
ISSN:	1472-6823
Megjegyzések:	Abstract Background: The implementation of population screening and early prevention strategies targeting individuals at high-risk for type 2 diabetes (T2D) seems to be a public health priority. The current work aimed to describe the screening procedure applied in the Feel4Diabetes-study and examine its effectiveness in identifying individuals and families at high risk, primarily for T2D and secondarily for hypertension, among vulnerable populations in low to middle-income countries (LMICs) and high-income countries (HICs) across Europe. Methods: A two-stage screening procedure, using primary schools as the entry-point to the community, was applied in low socioeconomic status (SES) regions in LMICs (Bulgaria-Hungary), HICs (Belgium-Finland) and HICs under austerity measures (Greece-Spain). During the first-stage screening via the school-setting, a total of 20,501 parents (mothers and/or fathers) of schoolchildren from 11,396 families completed the Finnish Diabetes Risk Score (FINDRISC) questionnaire, while their children underwent anthropometric measurements in the school setting. Parents from the identified "high-risk families" (n = 4484) were invited to participate in the second-stage screening, including the measurement of fasting plasma glucose (FPG) and blood pressure (BP). In total, 3153 parents participated in the second-stage screening (mean age 41.1 ? 5.6 years, 65.8% females). Results: Among parents who attended the second-stage screening, the prevalence of prediabetes (as defined by impaired fasting glucose; FPG 100-125 mg/dl) and T2D (FPG > 126 mg/dl) was 23.2 and 3.0% respectively, and it was found to be higher in the higher FINDRISC categories. The percentage of undiagnosed T2D among the participants identified with T2D was 53.5%. The prevalence of high normal BP (systolic BP 130-139mmHg and/ or diastolic BP 85- 89mmHg) and hypertension (systolic BP ? 140mmHg and/ or diastolic BP ? 90mmHg) was 14 and 18.6% respectively, which was also higher in the higher FINDRISC categories. The percentage of cases not receiving antihypertensive treatment among the participants identified with hypertension was 80.3%.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Hypertension School-based Screening Type 2 diabetes Vulnerable groups
Megjelenés:	BMC Endocrine Disorders. - 20 : S1 (2020), p. 1-12. -
További szerzők:	Mavrogianni, Christina Lambrinou, Christina-Paulina Cardon, Greet Lindström, Jaana Iotova, Violeta Tankova, Tsvetalina Civeira, Fernando Kivelä, Jemina Jancsó Zoltán (1973-) (orvos, háziorvos szakorvos, foglalkozás-orvostan szakorvos) Shadid, Samyah Tsochev, Kaloyan Mateo-Gallego, Rocío Radó Sándor Istvánné (1976-) (diplomás ápoló) Dafoulas, George Makrilakis, Konstantinos Androutsos, Odysseas Kolozsvári László Róbert (1977-) (háziorvos) Feel4Diabetes-Study Group
Pályázati támogatás:	The Feel4Diabetes-intervention is registered at https://clinicaltrials.gov/ (NCT02393872; date of trial registration: March 20, 2015). Egyéb
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