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001-es BibID:	BIBFORM086266
Első szerző:	Árkosy Péter (általános sebész, mellkassebész)
Cím:	Prognosis and Treatment Outcomes of Patients Undergoing Resection of Brain Metastases from Breast Cancer / Peter Arkosy, Judit Tóth, Edit Béres, Dezső Tóth, László Szívós, János Nagy, Almos Klekner, József Virga
Dátum:	2020
ISSN:	0250-7005 1791-7530
Megjegyzések:	Background: Brain metastases from breast cancer have poor prognosis and are a challenge to treat. Multiple treatment options are available. Descriptive and prognostic data on breast cancer brain metastases is limited. Patients and Methods: This study analyzed clinical data of patients who underwent surgical resection of one or more brain metastases. Histological and clinical characteristics, as well as treatment modalities, were analyzed. Results: Initial tumor stage or grade was found not to correlate with the median time to developing brain metastases or survival. Human epidermal growth factor receptor 2 (HER2)-positive status was not associated with shorter median time to developing brain metastases. No correlation was found between the number of brain metastases and patient outcome. Results confirm the survival benefit of surgical resection with or without irradiation. Conclusion: Data showed that patients with HER2-positive and those with triple-negative breast cancer develop brain metastases at lower stages but not earlier after diagnosis, and survival is mostly dependent on treatment modality rather than histological subtype.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk breast cancer brain metastasis molecular subtype prognosis surgical resection survival
Megjelenés:	Anticancer Research. - 40 : 3 (2020), p. 1759-1770. -
További szerzők:	Tóth Judit (1958-) (onkológus szakorvos) Béres Edit (1986-) (onkológus) Tóth Dezső (1972-) (sebész, onkológus) Szivos László (1993-) (idegsebész) Nagy János (1956-) (matematikus) Klekner Álmos (1970-) (idegsebész) Virga József (1989-)
Pályázati támogatás:	ÚNKP-19-3 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	bibEBI00026261
035-os BibID:	(cikkazonosító)6759 (Scopus)85090888156 (WOS)000581243900001
Első szerző:	Sipka Sándor (laboratóriumi szakorvos)
Cím:	Analysis of Low Cancer Mortality Rates in the Wine Regions of Tokaj and Balaton in Hungary / Sipka Sándor, Nagy János, Sipka Péter, Kocsis Judit, Tóth Judit, Árkosy Péter, Horváth Zsolt
Dátum:	2020
ISSN:	1661-7827 1660-4601
Megjegyzések:	The age-adjusted death rates (AADRs) due to cancers were investigated in two historical regions of white wines (Tokaj and Balaton) and in Hodmezovasarhely (HMV) as a control territory in Hungary between 2000 and 2010 evaluating 111,910 persons. The results of AADRs due to the eight most frequent types/gastrointestinal cancers were as follows: Tokaj 2120/664, Balaton: 2417/824, HMV: 2770/821, nationwide: 2773/887. The values found in Tokaj and Balaton regions were significantly less than those of HMV and nationwide. However, the least values were found in Tokaj. This Tokaj-related strong difference was not found among the regions in the case of young populations with hematological diseases but only in the older people who have been consuming their wines for decades. Supposedly, this wine-specific anti-cancer phenomenon could be related to the chemical differences existing in the two types of white wines, namely, to the pro-oxidant molecules of Tokaj wines derived from Botrytis cinerea. The roles of red meat consumption, hardness of drinking water, mineral content of soil, and socioeconomic status were negligible. It should be stressed that these data are valid only for these populations, for this period. Noteworthily, the different types of wines may have different effects on mortality rates during long-lasting consumptions. Keywords Author Keywords
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk age-adjusted death rate cancer wines of Balaton wines of Tokaj
Megjelenés:	International Journal of Environmental Research and Public Health. - 17 : 18 (2020), p. 1-8. -
További szerzők:	Nagy János (1956-) (matematikus) Sipka Péter Máté (1981-) (jogász) Kocsis Judit (1967-) (onkológus) Tóth Judit (1958-) (onkológus szakorvos) Árkosy Péter (1962-) (általános sebész, mellkassebész) Horváth Zsolt (1964-) (onkológus, belgyógyász, klinikai farmakológus)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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