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001-es BibID:	BIBFORM103008
035-os BibID:	(cikkazonosító)873899 (WOS)000836963900001 (Scopus)85135499583
Első szerző:	Csató Gábor
Cím:	Predictors of restenosis following percutaneous coronary stent implantation : the role of trimetazidine therapy / Csató Gábor, Erdei Nóra, Ványai Beatrix, Balla Tímea, Czuriga Dániel, Csanádi Zoltán, Koszegi Zsolt, Édes István, Szabó Gábor Tamás
Dátum:	2022
ISSN:	2297-055X
Megjegyzések:	Aims: In-stent restenosis (ISR) is an unresolved problem following percutaneous coronary intervention (PCI), having a negative impact on clinical outcome. The main goal of this study was to find new independent predictors that may influence the development of ISR. Methods and results: In this retrospective analysis, 653 PCI patients were involved. All patients had coronary stent implantation and a follow-up coronary angiography. Based on the presence of ISR at follow-up, patients were divided into two groups: 221 in the ISR and 432 in the control group. When evaluating the medical therapy of patients, significantly more patients were on trimetazidine (TMZ) in the control compared to the ISR group (p = 0.039). TMZ was found to be an independent predictor of a lower degree of ISR development (p = 0.007). TMZ treatment was especially e??ective in baremetal stent (BMS)-implanted chronic coronary syndrome (CCS) patients with narrow coronary arteries. The inflammation marker neutrophil to lymphocyte ratio (NLR) was significantly elevated at baseline in the ISR group compared to controls. The reduction of post-PCINLR was associated with improved e cacy of TMZ to prevent ISR development. Drug eluting stent implantation (p<0.001) and increased stent diameter (p<0.001) were themost important independent predictors of a lower degree of ISR development, while the use of longer stents (p = 0.005) was a major independent predictor of an increased ISR risk. Conclusion: TMZ reduces the occurrence of ISR following PCI, with special e??ectiveness in BMS-implanted patients having CCS and narrow coronary arteries. TMZ treatmentmay help to lower ISR formation in countries with high BMS utilization rates.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk in-stent restenosis trimetazidine (TMZ) percutaneous coronary intervention (PCI) anti-inflammatory effect stent implantation
Megjelenés:	Frontiers in Cardiovascular Medicine. - 9 (2022), p. 1-9. -
További szerzők:	Erdei Nóra (1979-) (orvos) Ványai Beatrix (1993-) (általános orvos) Balla Tímea Czuriga Dániel (1982-) (kardiológus) Csanádi Zoltán (1960-) (kardiológus) Kőszegi Zsolt (1962-) (kardiológus, belgyógyász) Édes István (1952-) (kardiológus) Szabó Gábor Tamás (1982-) (kardiológus)
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001-es BibID:	BIBFORM095124
035-os BibID:	(cikkazonosító)614493
Első szerző:	Ujvárosy Dóra
Cím:	Cardiopulmonary Resuscitation With Mechanical Chest Compression Device During Percutaneous Coronary Intervention : a case report / Dóra Ujvárosy, Veronika Sebestyén, Tamás Ötvös, Balázs Ratku, István Lorincz, Tibor Szuk, Zoltán Csanádi, Ervin Berényi, Zoltán Szabó
Dátum:	2021
ISSN:	2297-055X
Megjegyzések:	Sudden cardiac death is a leading cause of death worldwide, whereby myocardial infarction is considered the most frequent underlying condition. Percutaneous coronary intervention (PCI) is an important component of post-resuscitation care, while uninterrupted high-quality chest compressions are key determinants in cardiopulmonary resuscitation (CPR). In our paper, we evaluate a case of a female patient who suffered aborted cardiac arrest due to myocardial infarction. The ambulance crew providing prehospital care for sudden cardiac arrest used a mechanical chest compression device during advanced CPR, which enabled them to deliver ongoing resuscitation during transfer to the PCI laboratory located 20 km away from the scene. Mechanical chest compressions were continued during the primary coronary intervention. The resuscitation, carried out for 2 h and 35 min, and the coronary intervention were successful, as evidenced by the return of spontaneous circulation and by the fact that, after a short rehabilitation, the patient was discharged home with a favorable neurological outcome. Our case can serve as an example for the effective and safe use of a mechanical compression device during primary coronary intervention.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk sudden cardiac death cardiopulmonary resuscitation coronary intervention mechanical chest compression device
Megjelenés:	Frontiers in Cardiovascular Medicine. - 8 (2021), p. 1-6. -
További szerzők:	Borbásné Sebestyén Veronika (1990-) (biofizikus) Ötvös Tamás (1980-) (orvos) Ratku Balázs (1985-) (mentőtiszt) Lőrincz István (1950-) (belgyógyász, kardiológus) Szűk Tibor (1967-) (kardiológus) Csanádi Zoltán (1960-) (kardiológus) Berényi Ervin (1964-) (radiológus) Szabó Zoltán (1973-) (belgyógyász, kardiológus)
Pályázati támogatás:	GINOP-2.3.2-15-2016-00005 GINOP
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