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001-es BibID:BIBFORM029943
Első szerző:Bessenyei Mónika (neurológus, csecsemő- és gyermekgyógyász)
Cím:Characteristics of 4 stroke scales for the detection of changes in clinical signs in the acute phase of stroke / Bessenyei, M., Fekete, I., Csiba, L., Bereczki, D.
Dátum:2001
ISSN:1052-3057
Megjegyzések:OBJECTIVES: Detection of minor changes in clinical signs of stroke may be of interest when evaluating treatment interventions. This study analyzes the internal structure of four frequently used stroke scales and compares them for their sensitivity to detect changes in neurologic signs in the first week after acute stroke.METHODS:A cohort of 77 hospitalized acute stroke patients was scored by the Mathew, the National Institutes of Health (NIH), the Scandinavian, and the Orgogozo scales within 48 hours of hospital admission and again 7 days later.RESULTS:Scores on different scales correlated well with each other (range of absolute value of Spearman R, .82-.91; P <.001 in all comparisons). Scales reflected significant changes from entry to reexamination: P = .0013 for the Scandinavian scale (P = .004 for prognostic and P = .009 for long-term items, respectively); P = .00009 for the Orgogozo scale; P = .000007 for the Mathew scale; and P < .000001 for the NIH scale. This difference in sensitivity coincided with the number of factors extracted by principal component analysis: higher sensitivity of a scale was associated with a larger number of factors. Initial scores differed significantly among patients who were discharged, patients who died, and patients who remained hospitalized 7 days after the first examination (Kruskal-Wallis ANOVA, P < .01 for all scales).CONCLUSIONS:There are considerable differences in the internal structure of the different scales as reflected by the different number of factors extracted from the scale items. The application of the NIH scale is recommended for the most sensitive detection of changes in stroke signs.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 10 : 2 (2001), p. 70-78. -
További szerzők:Fekete István (1951-) (neurológus, pszichiáter) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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2.

001-es BibID:BIBFORM069439
Első szerző:Fekete Klára (neurológus)
Cím:Outcome of Repeated Thrombolysis in Debrecen Thrombolysis Database / Klára Fekete, Sándor Márton, László Csiba, István Fekete
Dátum:2017
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 26 : 1 (2017), p. 132-138. -
További szerzők:Márton Sándor (szociológus) Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
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3.

001-es BibID:BIBFORM062617
Első szerző:Fekete Klára (neurológus)
Cím:Predictors of Long-term Outcome after Intravenous or Intra-arterial Recombinant Tissue Plasminogen Activator Treatment in the Eastern Hungarian Thrombolysis Database / Klára Fekete, Sándor Márton, Judit Tóth, László Csiba, István Fekete, Dániel Bereczki
Dátum:2015
ISSN:1052-3057 1532-8511
Megjegyzések:Background: This prospective single-center study aimed to identify features determininglong-term outcome after thrombolysis in a Central European stroke population.Methods: Between 1 January, 2004, and 31 December, 2010, 415 patients weretreated with recombinant tissue plasminogen activator at the Department ofNeurology, University of Debrecen. Stroke severity by the National Institute ofHealth Stroke Scale score (NIHSSS) and imaging findings by the Alberta Stroke ProgrammeEarly Computed Tomography score (ASPECTS) were evaluated on admissionand 1 day later. The modified Rankin Scale (mRS) at 3 months and case fatalityat 1 year were evaluated. Independent predictors of outcome were identified bymultivariate testing. Results: Data of 369 patients were analyzed. Median NIHSSSwas 12 (interquartile range [IQR], 8-17) on admission and 10 (IQR, 5-16) at 24 hours.Arterial occlusion was found in 55%. Symptomatic intracerebral hemorrhage (SICH)was detected in 3.8%. Outcome was significantly worse, and SICH was morefrequent in intra-arterially treated patients. At 3 months, one third of the patientswere independent (mRS #2), and 23% were dead. At 1 year 2 of 3 patients were alive.Significant independent predictors of disability at 3 months were 24-hour NIHSSS,admission ASPECTS, admission glucose level, and treatment modality. Only the24-hour NIHSSS was a significant predictor of case fatality at 1 year. Conclusions:Although short-term outcome was similar, the 3-month and 1-year outcomes wereworse than data from previous reports. A more efficient health care program shouldbe implemented after stroke to maintain the favorable effect of thrombolysis in thelong term.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Ischemic stroke
thrombolysis
predictors
outcome
Megjelenés:Journal Of Stroke And Cerebrovascular Diseases. - 24 : 1 (2015), p. 117-124. -
További szerzők:Márton Sándor (szociológus) Tóth Judit Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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DOI
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