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001-es BibID:	BIBFORM113269
035-os BibID:	(WoS)000882514800006 (scopus)85141235387 (cikkazonosító)111805
Első szerző:	Botsi, Eirini
Cím:	Association of diet quality with glycemia, insulinemia, and insulin resistance in families at high risk for type 2 diabetes mellitus in Europe : Feel4 Diabetes Study / Botsi E., Karatzi K., Mavrogianni C., Kaloyan Tsochev, Esther M. González-Gil, Radó S., Kivelä J., Wikström K., Cardon G., Rurik I., Liatis S., Tsvetalina Tankova, Violeta Iotova, Luis A. Moreno, Makrillakis K., Manios Y., Tsigos C.
Dátum:	2023
ISSN:	0899-9007
Megjegyzések:	Objective The aim of the present study was to investigate the association of diet quality with fasting glycemia, insulinemia, and insulin resistance in a cross-sectional sample of adults from families at high risk for type 2 diabetes mellitus (T2DM) from six European countries, taking into account their socioeconomic status (SES). Methods Baseline data from non-diabetic adults from the Feel4 Diabetes study were used and diet was assessed by the Healthy Diet Score (HDS). Insulin resistance (IR) was determined by homeostasis model assessment of IR (HOMA-IR). Sociodemographic and lifestyle characteristics were assessed through standardized questionnaires. Multiple linear regressions were adjusted for many confounders, in the total sample and by SES category. Results In 1980 adults, the third tertile of diet quality was inversely associated with insulin levels (?1.48; 95% confidence interval [CI], ?2.34 to 0.62), and HOMA-IR (?0.33; 95% CI, ?0.57 to 0.09), yet with no statistically significant results for glucose levels. In the SES subgroup analysis, in the high SES group, both second and third diet score tertiles were inversely associated with insulin levels (?1.81; 95% CI, ?2.66 to 0.95) and HOMA-IR values (?0.45; 95% CI ?0.69 to 0.21), independent of age, sex, smoking and body mass index. No such associations were observed for glucose levels in the high SES group and for all indices in the low SES group. Conclusion In adults from families at high risk for T2DM, higher diet quality was negatively associated with fasting insulin levels and IR, only in the high SES group and not in the low SES group. Future larger studies may be able to explore further this association, as well as the potential factors that mitigate its strength in the low SES groups.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Nutrition. - 105 (2023), p. 1-6. -
További szerzők:	Karatzi, Kalliopi Mavrogianni, Christina Tsochev, Kaloyan González-Gil, Esther Radó Sándor Istvánné (1976-) (diplomás ápoló) Kivelä, Jemina Wikström, Katja Cardon, Greet Rurik Imre (1953-) (háziorvos, foglalkozás-egészségügyi szakorvos, urológus) Liatis, Stavros Tankova, Tsvetalina Iotova, Violeta Moreno, Luis A. Makrilakis, Konstantinos Manios, Yannis Tsigos, Constantine
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001-es BibID:	BIBFORM084100
Első szerző:	Kyrou, Ioannis
Cím:	Sociodemographic and lifestyle-related risk factors for identifying vulnerable groups for type 2 diabetes : a narrative review with emphasis on data from Europe / Kyrou Ioannis, Tsigos Constantine, Mavrogianni Christina, Cardon Greet, Van Stappen Vicky, Latomme Julie, Kivelä Jemina, Wikström Katja, Tsochev Kaloyan, Nanasi Anna, Semanova Csilla, Mateo-Gallego Rocío, Lamiquiz-Moneo Itziar, Dafoulas George, Timpel Patrick, Schwarz Peter E. H., Iotova Violeta, Tankova Tsvetalina, Makrilakis Konstantinos, Manios Yannis, Feel4Diabetes-Study Group
Dátum:	2020
ISSN:	1472-6823
Megjegyzések:	Abstract Background: Type 2 diabetes mellitus (T2DM) comprises the vast majority of all diabetes cases in adults, with alarmingly increasing prevalence over the past few decades worldwide. A particularly heavy healthcare burden of diabetes is noted in Europe, where 8.8% of the population aged 20?79 years is estimated to have diabetes according to the International Diabetes Federation. Multiple risk factors are implicated in the pathogenesis of T2DM with complex underlying interplay and intricate gene-environment interactions. Thus, intense research has been focused on studying the role of T2DM risk factors and on identifying vulnerable groups for T2DM in the general population which can then be targeted for prevention interventions. Methods: For this narrative review, we conducted a comprehensive search of the existing literature on T2DM risk factors, focusing on studies in adult cohorts from European countries which were published in English after January 2000. Results: Multiple lifestyle-related and sociodemographic factors were identified as related to high T2DM risk, including age, ethnicity, family history, low socioeconomic status, obesity, metabolic syndrome and each of its components, as well as certain unhealthy lifestyle behaviors. As Europe has an increasingly aging population, multiple migrant and ethnic minority groups and significant socioeconomic diversity both within and across different countries, this review focuses not only on modifiable T2DM risk factors, but also on the impact of pertinent demographic and socioeconomic factors. Conclusion: In addition to other T2DM risk factors, low socioeconomic status can significantly increase the risk for prediabetes and T2DM, but is often overlooked. In multinational and multicultural regions such as Europe, a holistic approach, which will take into account both traditional and socioeconomic/socioecological factors, is becoming increasingly crucial in order to implement multidimensional public health programs and integrated community-based interventions for effective T2DM prevention.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Diet Ethnicity Lifestyle Obesity Risk factors Socioeconomic status Type 2 diabetes
Megjelenés:	BMC Endocrine Disorders. - 20 : Suppl. 1 (2020), p. 1-13. -
További szerzők:	Tsigos, Constantine Mavrogianni, Christina Cardon, Greet Van Stappen, Vicky Latomme, Julie Kivelä, Jemina Wikström, Katja Tsochev, Kaloyan Nánási Anna (1995-) (háziorvos) Semánová Csilla (1991-) (PhD hallgató) Mateo-Gallego, Rocío Lamiquiz-Moneo, Itziar Dafoulas, George Timpel, Patrick Schwarz, Peter E. H. Iotova, Violeta Tankova, Tsvetalina Makrilakis, Konstantinos Manios, Yannis Kolozsvári László Róbert (1977-) (háziorvos) Rurik Imre (1953-) (háziorvos, foglalkozás-egészségügyi szakorvos, urológus) Jancsó Zoltán (1973-) (orvos, háziorvos szakorvos, foglalkozás-orvostan szakorvos) Ungvári Tímea Feel4Diabetes-Study Group
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