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001-es BibID:	BIBFORM021460
Első szerző:	Galuska László (belgyógyász, izotópdiagnoszta)
Cím:	The clinical usefulness of the fingers-to-palm ratio in different hand microcirculatory abnormalities / L. Galuska, I. Garai, Z. Csiki, J. Varga, E. Bodolay, L. Bajnok
Dátum:	2000
ISSN:	0143-3636
Megjegyzések:	A non-invasive nuclear medicine technique was developed to screen patients with painful hands so as to separate patients with a normal from those with an abnormal microcirculation of the hands in different clinical conditions. Such a technique is important, as the other methods available are either subjective or rather complicated. The study population consisted of 10 healthy individuals, 23 patients with Raynaud's syndrome and 15 patients with mixed connective tissue disease (MCTD). Sixty gamma-camera images of the hands (1 s each) were recorded after a bolus injection of 99Tcm-DTPA via a dorsal foot vein. Regions of interest were drawn on the summed images around the fingers and the palmar region. The fingers-to-palm ratio was then calculated from the total counts inside these regions of interest separately for each hand. The mean fingers-to-palm ratio was 0.94+/-0.18 (0.71-1.25) for the healthy group, 0.57+/-0.22 (0.21+/-1.11) for the MCTD group and 0.40+/-0.14 (0.18-0.77) for the Raynaud's patients. Analysis of variance showed these differences to be highly significant (P < 0.001). There were also significant differences between 6 MCTD patients in an active (mean 0.48) and nine patients in an inactive (mean 0.66) clinical state (two-sample t-test: P < 0.05). There were no significant differences between the fingers-to-palm ratios of the left and right hands of the same patients (one-sample t-test). Of the 23 primary Raynaud's patients, capillary microscopic data were pathological in only eight (34%). We conclude that our method is able to differentiate between patients with normal and those with abnormal microcirculation of the hands. Although measurement of the fingers-to-palm ratio is not a specific method, it is useful both for staging and in the follow-up of patients.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban the clinical usefulness egyetemen (Magyarországon) készült közlemény
Megjelenés:	Nuclear Medicine Communications. - 21 : 7 (2000), p. 659-663. -
További szerzők:	Garai Ildikó (1966-) (radiológus) Csiki Zoltán (1962-) (belgyógyász, allergológus, klinikai immunológus, reumatológus) Varga József (1955-) (fizikus) Bodolay Edit (1950-) (belgyógyász, allergológus és klinikai immunológus) Bajnok László (1961-) (belgyógyász)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM019775
Első szerző:	Galuska László (belgyógyász, izotópdiagnoszta)
Cím:	Az ujj-tenyér keringési hányados radionuklid meghatározása microcirkulációs zavarokban / Galuska László, Garai Ildikó, Csiki Zoltán, Varga József, Bodolay Edit, Bajnok László
Dátum:	1999
Megjegyzések:	A non-invasive nuclear medicine method was developed for screening patients (PTS) with painful hands, in order to separate PTS with normal from those with abnormal microcirculation (MIC) of the hands in different clinical conditions. Such a method would be of great importance as the other methods available are either importance as the other methods available are either subjective or rather complicated. The study comprised ten healthy individuals, twenty-three PTS with Raynaud syndrome (RS), and fifteen PTS with mixed connective tissue disease (MCTD) - 6 active and 9 inactive. After the bolus injection of 99mTc-DTPA through a dorsal foot vein, dynamic study was performed during 1 min. (1 sec/game images). Regions of interest (ROIs) were drawn on the summed images around the fingers, and the palmar region. The fingers-to-palm ratio (FPR) is then calculated from the total counts inside these ROIs separately for each hand. Mean FPR was 0.94+-0.18 (0.71-1.25) for the healthy group, 0.57+-0.22 (0.21-1.11) for the MCTD group, and 0.40+-0.14 (0.18-0.77) for the Raynaud PTS. Variance analysis showed these differences to be highly significant (P<0.001). There were also significant differences between 6 MTCD PTS in active (mean 0.48) and 9 in inactive (mean 0.66) clinical state (2 sample t-test: P<0.05). However, there were no significant differences between the FPR values of left and right hands of the same patient (1 sample t-test). From among the 23 primary Raynaud PTS, capillary microscopic data were pathological in only 8 cases (34 per cent). We conclude that our method is capable for differentiating PTS with normal from those with abnormal MIC of the hands. Though the FPR measurement is not a specific method, it is useful both for staging and in the follow-up of PTS.
Tárgyszavak:	Orvostudományok Egészségtudományok magyar nyelvű folyóiratközlemény hazai lapban ujj-tenyér egyetemen (Magyarországon) készült közlemény
Megjelenés:	Érbetegségek. - 6 : 4 (1999), p. 127-131. -
További szerzők:	Garai Ildikó (1966-) (radiológus) Csiki Zoltán (1962-) (belgyógyász, allergológus, klinikai immunológus, reumatológus) Varga József (1955-) (fizikus) Bodolay Edit (1950-) (belgyógyász, allergológus és klinikai immunológus) Bajnok László (1961-) (belgyógyász)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: