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001-es BibID:	BIBFORM076659
Első szerző:	Moussa, Mariam
Cím:	Co-culture of the fungus Fusarium tricinctum with Streptomyces lividans induces production of cryptic naphthoquinone dimers / Mariam Moussa, Weaam Ebrahim, Michele Bonus, Holger Gohlke, Attila Mandi, Tibor Kurtan, Rudolf Hartmann, Rainer Kalscheuer, Wenhan Lin, Zhen Liu, Peter Proksch
Dátum:	2019
ISSN:	2046-2069 2046-2069
Megjegyzések:	Co-cultivation of the endophytic fungus Fusarium tricinctum with Streptomyces lividans on solid rice medium led to the production of four new naphthoquinone dimers, fusatricinones A-D (1-4), and a new lateropyrone derivative, dihydrolateropyrone (5), that were not detected in axenic fungal controls. In addition, four known cryptic compounds, zearalenone (7), (_)-citreoisocoumarin (8), macrocarpon C (9) and 7-hydroxy-2-(2-hydroxypropyl)-5-methylchromone (10), that were likewise undetectable in extracts from fungal controls, were obtained from the co-culture extracts. The known antibiotically active compound lateropyrone (6), the depsipeptides enniatins B (11), B1 (12) and A1 (13), and the lipopeptide fusaristatin A (14), that were present in axenic fungal controls and in co-culture extracts, were upregulated in the latter. The structures of the new compounds were elucidated by 1D and 2D NMR spectra as well as by HRESIMS data. The relative and absolute configuration of dihydrolateropyrone (5) was elucidated by TDDFT-ECD calculations.
Tárgyszavak:	Természettudományok Földtudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	RSC Advances. - 9 : 3 (2019), p. 1491-1500. -
További szerzők:	Ebrahim, Weaam Bonus, Michele Gohlke, Holger Mándi Attila (1981-) (vegyész, német szakfordító) Kurtán Tibor (1973-) (vegyész, angol szakfordító) Hartmann, Rudolf Kalscheuer, Rainer Lin, Wen Han Liu, Zhen Proksch, Peter
Pályázati támogatás:	NKFI K120181 Egyéb NKFI PD121020 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM065178
Első szerző:	Moussa, Mariam
Cím:	Tetrahydroanthraquinone derivatives from the mangrove-derived endophytic fungus Stemphylium globuliferum / Mariam Moussa, Weaam Ebrahim, Mona El-Neketi, Attila Mándi, Tibor Kurtán, Rudolf Hartmann, Wenhan Lin, Zhen Liu, Peter Proksch
Dátum:	2016
ISSN:	0040-4039
Megjegyzések:	Two new tetrahydroanthraquinone derivatives, altersolanol Q (1) and 10-methylaltersolanol Q (2), and the new dimer alterporriol X (3), together with 13 known analogues were isolated from white bean solid culture media of the endophytic fungus, Stemphylium globuliferum, obtained from the Egyptian mangrove plant Avicennia marina. The present study resulted in the production of a large diversity of secondary metabolites including new derivatives. Their structures were elucidated using one- and two-dimensional NMR spectroscopy as well as HRESIMS. The absolute configurations of the new compounds 1?3 were determined by TDDFT-ECD calculations or by comparing ECD data with those of known analogues. Compounds 1?3 were tested against the L5178Y mouse lymphoma cell line but proved to be inactive in contrast to some of the known compounds such as altersolanol A (6) that were likewise isolated in this study.
Tárgyszavak:	Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban Stemphylium globuliferum Tetrahydroanthraquinone ECD calculations
Megjelenés:	Tetrahedron Letters. - 57 : 36 (2016), p. 4074-4078. -
További szerzők:	Ebrahim, Weaam El-Neketi, Mona Mándi Attila (1981-) (vegyész, német szakfordító) Kurtán Tibor (1973-) (vegyész, angol szakfordító) Hartmann, Rudolf Lin, Wen Han Liu, Zhen Proksch, Peter
Pályázati támogatás:	K105871 OTKA NIIFI 10038 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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