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001-es BibID:BIBFORM080564
035-os BibID:(PMID)31228077
Első szerző:Nyilas Renáta
Cím:Interim PET/CT in diffuse large B-cell lymphoma may facilitate identification of good-prognosis patients among IPI-stratified patients / Renata Nyilas, Bence Farkas, Reka Rahel Bicsko, Ferenc Magyari, Laszlo Imre Pinczes, Arpad Illes, Lajos Gergely
Dátum:2019
ISSN:0925-5710 1865-3774
Megjegyzések:Treating patients with DLBCL remains a challenge, as the response to first-line immunochemotherapy is somewhat unpredictable. The International Prognostic Index (IPI) is one of the most widely used methods for assessing prognosis. Interim PET/CT (iPET/CT) can play an important role in the early identification of 'non-responder' patients before the end of treatment examination. In this study, we retrospectively analyzed 104 newly diagnosed DLBCL patients treated with R-CHOP-like regimens who underwent iPET/CT imaging during therapy. There was a significant difference in 2-year OS between patients with negative iPET/CT and those with positive iPET/CT. Patients who had positive iPET/CT showed inferior 2-year PFS compared to those with negative iPET/CT. According to IPI, there was a statistically significant difference in 2-year OS and PFS between patients in the lower and higher risk groups. However, these patients can be further subdivided according to iPET/CT. The iPET/CT results in the present study clearly separate good- and poor-prognosis patients according to differences in 2-year OS, both in the lower and higher IPI risk groups. These results are in agreement with those of previous studies that demonstrated that iPET/CT has high negative predictive value, clearly identifying good-prognosis patients even within the poor-prognosis IPI group.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
DLBCL
Diffuse large B-cell lymphoma
Interim PET/CT
PET/CT
Response
Megjelenés:International Journal of Hematology. - 110 : 3 (2019), p. 331-339. -
További szerzők:Farkas Bence Bicskó Réka Ráhel (1994-) (általános orvos) Magyari Ferenc (1985-) (belgyógyász, hematológus) Pinczés László Imre (1990-) (általános orvos) Illés Árpád (1959-) (belgyógyász, haematológus, onkológus) Gergely Lajos (1965-) (belgyógyász, haematológus)
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001-es BibID:BIBFORM113353
035-os BibID:(cikkazonosító)901 (WoS)001036718100001 (Scopus)85166573620
Első szerző:Udvardy Miklós (belgyógyász, haematológus)
Cím:Transfusion-Transmitted Disorders 2023 with Special Attention to Bone Marrow Transplant Patients / Udvardy Miklós, Illés Árpád, Gergely Lajos, Pinczés László Imre, Magyari Ferenc, Simon Zsófia
Dátum:2023
ISSN:2076-0817
Megjegyzések:Transfusion medicine is traditionally a strong/fundamental part of clinical practice, saving hundreds of millions of lives. However, blood-borne or transmitted infections are a well-known and feared possibility, a risk we relentlessly mitigate. Pathogens are continuously and rather quickly changing, so during the last decade, many, sometimes exotic, new pathogens and diseases were recorded and analyzed, and some of them were proved to be transmitted with transfusions. Blood or blood component transfusions are carried out after cautious preparative screening and inactivation maneuvers, but in some instances, newly recognized agents might escape from standard screening and inactivation procedures. Here, we try to focus on some of these proven or potentially pathogenic transfusion-transmitted agents, especially in immunocompromised patients or bone marrow transplantation settings. These pathogens are sometimes new challenges for preparative procedures, and there is a need for more recent, occasionally advanced, screening and inactivation methods to recognize and eliminate the threat a new or well-known pathogen can pose. Pathogen transmission is probably even more critical in hemophiliacs or bone marrow transplant recipients, who receive plasma-derived factor preparations or blood component transfusions regularly and in large quantities, sometimes in severely immunosuppressed conditions. Moreover, it may not be emphasized enough that transfusions and plasma-derived product administrations are essential to medical care. Therefore, blood-borne transmission needs continued alertness and efforts to attain optimal benefits with minimized hazards.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Pathogens. - 12 : 7 (2023), p. 1-17. -
További szerzők:Illés Árpád (1959-) (belgyógyász, haematológus, onkológus) Gergely Lajos (1965-) (belgyógyász, haematológus) Pinczés László Imre (1990-) (általános orvos) Magyari Ferenc (1985-) (belgyógyász, hematológus) Simon Zsófia (1977-) (belgyógyász, haematológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
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