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001-es BibID:	BIBFORM079822
Első szerző:	Fekete Klára (neurológus)
Cím:	Effectiveness and outcome of intravenous (IV) and intra-arterial (IA) thrombolysis in the Eastern Hungarian Stroke Center / K. Fekete, I. Fekete, D. Bereczki, T. Magyar, L. Olah, T. Csepany, L. Csiba
Dátum:	2009
ISSN:	1351-5101
Megjegyzések:	Introduction: IV and IA thrombolysis is an effective treatment in acute ischemic stroke. Effectiveness and side effects were tested in the database. Methods: We treated 208 patients with IV/IA (145/63 pts) rt-PA after onset of ischemic stroke. After urgent CT, CTA we administered 0.9 mg/kg rt-PA according to the protocol. At local thrombolysis after 5 mg rt-PA bolus, 1 mg/min infusionwasadministered.GCS,NIHSSwereexaminedon the admission and after 7 days, mRS after 3 months. Risk factors and time window of stroke were estimated, too. Results: 64% of patients were male and 36% female.Time window was within 120min by 28% of patients, 180min 44%, 4.5h 17% and more than 270min 11% (for IA thrombolysis)afterstrokeonset.Averageagewas66.5?13.9 and 67.3?14.7 years.The most important risk factors were: hypertension (68.5%), atrial fibrillation (17%), other heart disorders(20%),smoking18.5%),diabetesmellitus(16%), hypercholesterolemia(19%),previousstrokeorTIA(16%). The average of NIHSS before thrombolysis was 14 (2-25), after 24 hours 11 (0-25). Hemorrhagic transformation was 13% after IA, 4.4% after IV administration of rt-PA. Intracerebral haemorrhage was recognized in 17.6% after IA,4.4%IV .Mortalitywas3%within24hours,21%within 3 months (IA: 27.9%, IV:13%). Large artery re-opening after IA thrombolysis was 46%. The proportion of independent patients was 36.4% (mRS) at 3 months. Conclusion: Beside IV thrombolysis IA administration of rt-PA is effective in acute stroke, but ICH and hemorrhagic transformation rate is more frequent
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt thrombolysis
Megjelenés:	European Journal of Neurology. - 16 : Suppl. 3 (2009), p. 393. -
További szerzők:	Fekete István (1951-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus) Magyar T. Oláh László (1967-) (neurológus) Csépány Tünde (1956-) (neurológus, pszichiáter) Csiba László (1952-) (neurológus, pszichiáter)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	bibEBI16618
Első szerző:	Fülesdi Béla (aneszteziológus)
Cím:	Evaluation of the cerebrovascular reserve capacity in asymptomatic and symptomatic carotid artery abstructive disease / Fülesdi, B., Káposzta, Z., Molnár, Cs., Oláh, L., Limburg, M., Valikovics, A., Csiba, L.
Dátum:	1995
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt egyetemen (Magyarországon) készült közlemény
Megjelenés:	European Journal of Neurology. - 2 : Suppl.2 (1995), p. 21. -
További szerzők:	Káposzta Zoltán Molnár Csilla (1962-) (aneszteziológus) Oláh László (1967-) (neurológus) Limburg, Martien Valikovics Attila Csiba László (1952-) (neurológus, pszichiáter)
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001-es BibID:	BIBFORM050854
035-os BibID:	WOS:000324099200017
Első szerző:	Mezei Zsolt (neurológus)
Cím:	Cerebrovascular hemodynamic changes in multiple sclerosis patients during head-up tilt table test : effect of high-dose intravenous steroid treatment / Zsolt Mezei, Laszlo Olah, Laszlo Kardos, Reka Katalin Kovacs, Laszlo Csiba, Tunde Csepany
Dátum:	2013
ISSN:	0340-5354
Megjegyzések:	Demyelination in multiple sclerosis (MS) may cause damage to the vegetative nervous system. Our objective was to examine cerebral autoregulation assessed via blood pressure and cerebral blood flow velocity fluctuations during head-up tilt table testing. We also investigated the effects of high-dose intravenous corticosteroid treatment. Transcranial Doppler registration of middle cerebral artery blood flow velocity and continuous blood pressure and heart rate monitoring were performed at rest and during tilt table testing in 30 MS patients. Ten age-matched healthy subjects were also examined as controls. Correlations between mean arterial blood pressure (MBP) and cerebral blood flow velocity (CBF) fluctuations were averaged, yielding the correlation coefficient index Mx. For a subgroup of 11 patients with acute exacerbations, results were also evaluated before and after methylprednisolone treatment (1 g/day intravenously for 5 days). No significant differences in the autoregulatory indices were seen between patients and controls, or between pre- and post-steroid results. Modeling CBF velocity changes associated with a 1-mmHg increase in MBP, significant differences (p < 0.05) were detected in patients vs. controls, and also after vs. before steroid administration. We conclude that cerebrovascular autoregulation impairments are detectable in early phase MS. Corticosteroid treatment has a significant effect on hemodynamic changes in acute exacerbations.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Journal of Neurology. - 260 : 9 (2013), p. 2335-2342. -
További szerzők:	Oláh László (1967-) (neurológus) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Czuriga-Kovács Katalin Réka (1981-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter) Csépány Tünde (1956-) (neurológus, pszichiáter)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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