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001-es BibID:BIBFORM053793
Első szerző:Molnár Zsuzsanna (szülész-nőgyógyász, labor szakorvosjelölt, urológus)
Cím:Fertility of testicular cancer patients after anticancer treatment : experience of 11 years / Z. Molnár, E. Berta, M. Benyó, R. Póka, Z. Kassai, T. Flaskó, A. Jakab, M. Bodor
Dátum:2014
ISSN:0031-7144
Megjegyzések:Testicular cancer affects men mostly in their reproductive age with a cure rate over 90%. Preserved fertilityis one of the main concerns of the survivors. To further elucidate the question of fertility after anticancertreatment for testicular cancer, we performed a survey among patients who underwent spermcryopreservationprocedure in our department. A structured questionnaire was designed to collect data on demography,anticancer treatment, histological type of cancer, family planning intentions and fertility prior to and aftertreatment. During a period of 11 years 86 men underwent semen cryopreservation before starting chemoorradiotherapy. Fifty-nine of them consented to participate in the study. The average length of follow upwas 4.6?3.8 years. In case of 11.9% of the patients their banked sperm was used, which led to live birthin 57% of the couples. The partners of 6 patients became pregnant after in vitro fertilization (IVF) resultingin 4 live births and 2 miscarriages. The spontaneous pregnancy rate was 22%. Spontaneous pregnancyoccurred in 13 partners resulting in 18 pregnancies followed by 12 live births, 2 artificial abortions and 4miscarriages. We could not prove any association between preserved fertility and anticancer treatment orthe histological type of the cancer. In conclusion, although spontaneous pregnancy rate is remarkably highafter anticancer treatment for testicular cancer, the risk of infertility after receiving gonadotoxic treatmentcannot be predicted. Cryopreservation is a safe and effective method to preserve fertility in these cases.As a result we strongly recommend discussing the advantages of semen cryopreservation with all patientsawaiting treatment for testicular cancer.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Pharmazie 69 : 6 (2014), p. 437-441. -
További szerzők:Berta Eszter (1980-) (belgyógyász) Benyó Mátyás (1982-) (urológus) Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Bazsáné Kassai Zsuzsa (1946-) (embriológus) Flaskó Tibor (1960-) (urológus) Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Bodor Miklós (1969-) (belgyógyász, endokrinológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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