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001-es BibID:	BIBFORM107355
035-os BibID:	(scopus)85132842261 (wos)000834619400012
Első szerző:	van der Vlegel, Marjolein
Cím:	Health care utilization and outcomes in older adults after Traumatic Brain Injury : a CENTER-TBI study / van der Vlegel Marjolein, Mikolic Ana, Lee Hee Quentin, Kaplan Z. L. Rana, Retel Helmrich Isabel R. A., van Veen Ernest, Andelic Nada, Steinbuechel Nicole v., Plass Anne Marie, Zeldovich Marina, Wilson Lindsay, Maas Andrew I. R., Haagsma Juanita A., Polinder Suzanne, CENTER-TBI Participants and Investigators
Dátum:	2022
ISSN:	0020-1383
Megjegyzések:	Introduction: The incidence of Traumatic Brain Injury (TBI) is increasingly common in older adults aged ?65 years, forming a growing public health problem. However, older adults are underrepresented in TBI research. Therefore, we aimed to provide an overview of health-care utilization, and of six-month out- comes after TBI and their determinants in older adults who sustained a TBI. Methods: We used data from the prospective multi-center Collaborative European NeuroTrauma Effective- ness Research in Traumatic Brain Injury (CENTER-TBI) study. In-hospital and post-hospital health care uti- lization and outcomes were described for patients aged ?65 years. Ordinal and linear regression analyses were performed to identify determinants of the Glasgow Outcome Scale Extended (GOSE), health-related quality of life (HRQoL), and mental health symptoms six-months post-injury. Results: Of 1254 older patients, 45% were admitted to an ICU with a mean length of stay of 9 days. Nearly 30% of the patients received inpatient rehabilitation. In total, 554/1254 older patients completed the six- month follow-up questionnaires. The mortality rate was 9% after mild and 60% after moderate/severe TBI, and full recovery based on GOSE was reported for 44% of patients after mild and 6% after moderate/severe TBI. Higher age and increased injury severity were primarily associated with functional impairment, while pre-injury systemic disease, psychiatric conditions and lower educational level were associated with func- tional impairment, lower generic and disease-specific HRQoL and mental health symptoms. Conclusion: The rate of impairment and disability following TBI in older adults is substantial, and poorer outcomes across domains are associated with worse preinjury health. Nonetheless, a considerable number of patients fully or partially returns to their preinjury functioning. There should not be pessimism about outcomes in older adults who survive
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Traumatic Brain Injury Older adults Outcomes Health care utilization Health-related quality of life Mental health
Megjelenés:	Injury-International Journal Of The Care Of The Injured. - 53 : 8 (2022), p. 2774-2782. -
További szerzők:	Mikolić, Ana Lee Hee, Quentin Kaplan, Z. L. Rana Retel Helmrich, Isabel R. A. van Veen, Ernest Andelic, Nada von Steinbuechel, Nicole Plass, Anne Marie Zeldovich, Marina Wilson, Lindsay Maas, Andrew I. R. Haagsma, Juanita A. Polinder, Suzanne Sándor János (1966-) (orvos-epidemiológus) CENTER-TBI Participants and Investigators
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001-es BibID:	BIBFORM107433
035-os BibID:	(scopus)85087993373 (wos)000548832800001
Első szerző:	Voormolen, Daphne C.
Cím:	Health-related quality of life after traumatic brain injury : deriving value sets for the QOLIBRI-OS for Italy, The Netherlands and The United Kingdom / Voormolen Daphne C., Polinder Suzanne, von Steinbuechel Nicole, Feng Yan, Wilson Lindsay, Oppe Mark, Haagsma Juanita A., CENTER-TBI participants and investigators
Dátum:	2020
ISSN:	0962-9343
Megjegyzések:	Purpose The Quality of Life after Brain Injury overall scale (QOLIBRI-OS) measures health-related quality of life (HRQoL) after traumatic brain injury (TBI). The aim of this study was to derive value sets for the QOLIBRI-OS in three European countries, which will allow calculation of utility scores for TBI health states. Methods A QOLIBRI-OS value set was derived by using discrete choice experiments (DCEs) and visual analogue scales (VAS) in general population samples from the Netherlands, United Kingdom and Italy. A three-stage procedure was used: (1) A selection of health states, covering the entire spectrum of severity, was defned; (2) General population samples performed the health state valuation task using a web-based survey with three VAS questions and an at random selection of sixteen DCEs; (3) DCEs were analysed using a conditional logistic regression and were then anchored on the VAS data. Utility scores for QOLIBRI-OS health states were generated resulting in estimates for all potential health states. Results The questionnaire was completed by 13,623 respondents. The biggest weight increase for all attributes is seen from "slightly" to "not at all satisfed", resulting in the largest impact on HRQoL. "Not at all satisfed with how brain is working" should receive the greatest weight in utility calculations in all three countries. Conclusion By transforming the QOLIBRI-OS into utility scores, we enabled the application in economic evaluations and in summary measures of population health, which may be used to inform decision-makers on the best interventions and strategies for TBI patients.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Health-related quality of life Quality of life after brain injury overall scale (QOLIBRI-OS) Health utilities Value set Traumatic brain injury
Megjelenés:	Quality Of Life Research. - 29 : 11 (2020), p. 3095-3107. -
További szerzők:	Polinder, Suzanne von Steinbuechel, Nicole Feng, Yan Wilson, Lindsay Oppe, Mark Haagsma, Juanita A. Sándor János (1966-) (orvos-epidemiológus) CENTER-TBI Participants and Investigators
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