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001-es BibID:	BIBFORM107361
035-os BibID:	(cikkazonosító)1536 (scopus)85144238216
Első szerző:	Howe, Emilie Isager
Cím:	Rehabilitation and outcomes after complicated vs uncomplicated mild TBI : results from the CENTER-TBI study / Howe Emilie Isager, Zeldovich Marina, Andelic Nada, von Steinbuechel Nicole, Fure Silje C. R., Borgen Ida M. H., Forslund Marit V., Hellstrm Torgeir, Sberg Helene L., Sveen Unni, Rasmussen Mari, Kleffelgaard Ingerid, Tverdal Cathrine, Helseth Eirik, Lvstad Marianne, Lu Juan, Arango-Lasprilla Juan Carlos, Tenovuo Olli, Azouvi Philippe, Dawes Helen, Roe Cecilie, CENTER-TBI participants and investigators
Dátum:	2022
ISSN:	1472-6963
Megjegyzések:	Background: Despite existing guidelines for managing mild traumatic brain injury (mTBI), evidence-based treat? ments are still scarce and large-scale studies on the provision and impact of specifc rehabilitation services are needed. This study aimed to describe the provision of rehabilitation to patients after complicated and uncomplicated mTBI and investigate factors associated with functional outcome, symptom burden, and TBI-specifc health-related quality of life (HRQOL) up to six months after injury. Methods: Patients (n=1379) with mTBI from the Collaborative European NeuroTrauma Efectiveness Research in TBI (CENTER-TBI) study who reported whether they received rehabilitation services during the frst six months post-injury and who participated in outcome assessments were included. Functional outcome was measured with the Glasgow Outcome Scale ? Extended (GOSE), symptom burden with the Rivermead Post Concussion Symptoms Questionnaire (RPQ), and HRQOL with the Quality of Life after Brain Injury ? Overall Scale (QOLIBRI-OS). We examined whether transi? tion of care (TOC) pathways, receiving rehabilitation services, sociodemographic (incl. geographic), premorbid, and injury-related factors were associated with outcomes using regression models. For easy comparison, we estimated ordinal regression models for all outcomes where the scores were classifed based on quantiles. Results: Overall, 43% of patients with complicated and 20% with uncomplicated mTBI reported receiving rehabili? tation services, primarily in physical and cognitive domains. Patients with complicated mTBI had lower functional level, higher symptom burden, and lower HRQOL compared to uncomplicated mTBI. Rehabilitation services at three or six months and a higher number of TOC were associated with unfavorable outcomes in all models, in addition to pre-morbid psychiatric problems. Being male and having more than 13 years of education was associated with more favorable outcomes. Sustaining major trauma was associated with unfavorable GOSE outcome, whereas living in Southern and Eastern European regions was associated with lower HRQOL
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk traumatic brain injury
Megjelenés:	BMC Health Services Research. - 22 : 1 (2022), p. 1-16. -
További szerzők:	Zeldovich, Marina Andelic, Nada von Steinbuechel, Nicole Fure, Silje C. R. Borgen, Ida M. H. Forslund, Marit V. Hellstrm, Torgeir Sberg, Helene L. Sveen, Unni Rasmussen, Mari Kleffelgaard, Ingerid Tverdal, Cathrine Helseth, Eirik Lvstad, Marianne Lu, Juan Arango-Lasprilla, Juan Carlos Tenovuo, Olli Azouvi, Philippe Dawes, Helen Roe, Cecilie Sándor János (1966-) (orvos-epidemiológus) CENTER-TBI Participants and Investigators
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001-es BibID:	BIBFORM107449
035-os BibID:	(scopus)85089102230 (wos)000557530500001
Első szerző:	Jacob, Louis
Cím:	Predictors of Access to Rehabilitation in the Year Following Traumatic Brain Injury : a European Prospective and Multicenter Study / Jacob Louis, Cogné Mélanie, Tenovuo Olli, Re Cecilie, Andelic Nada, Majdan Marek, Ranta Jukka, Ylen Peter, Dawes Helen, Azouvi Philippe, CENTER-TBI Participants and Investigators
Dátum:	2020
ISSN:	1545-9683
Megjegyzések:	Background. Although rehabilitation is beneficial for individuals with traumatic brain injury (TBI), a significant proportion of them do not receive adequate rehabilitation after acute care. Objective. Therefore, the goal of this prospective and multicenter study was to investigate predictors of access to rehabilitation in the year following injury in patients with TBI. Methods. Data from a large European study (CENTER-TBI), including TBIs of all severities between December 2014 and December 2017 were used (N = 4498 patients). Participants were dichotomized into those who had and those who did not have access to rehabilitation in the year following TBI. Potential predictors included sociodemographic factors, psychoactive substance use, preinjury medical history, injury-related factors, and factors related to medical care, complications, and discharge. Results. In the year following traumatic injury, 31.4% of patients received rehabilitation services. Access to rehabilitation was positively and significantly predicted by female sex (odds ratio [OR] = 1.50), increased number of years of education completed (OR = 1.05), living in Northern (OR = 1.62; reference: Western Europe) or Southern Europe (OR = 1.74), lower prehospital Glasgow Coma Scale score (OR = 1.03), higher Injury Severity Score (OR = 1.01), intracranial (OR = 1.33) and extracranial (OR = 1.99) surgery, and extracranial complication (OR = 1.75). On contrast, significant negative predictors were lack of preinjury employment (OR = 0.80), living in Central and Eastern Europe (OR = 0.42), and admission to hospital ward (OR = 0.47; reference: admission to intensive care unit) or direct discharge from emergency room (OR = 0.24). Conclusions. Based on these findings, there is an urgent need to implement national and international guidelines and strategies for access to rehabilitation after TBI.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk traumatic brain injury rehabilitation predictive factors international prospective study Europe
Megjelenés:	Neurorehabilitation And Neural Repair. - 34 : 9 (2020), p. 814-830. -
További szerzők:	Cogné, Mélanie Tenovuo, Olli Re, Cecilie Andelic, Nada Majdan, Marek Ranta, Jukka Ylen, Peter Dawes, Helen Azouvi, Philippe Sándor János (1966-) (orvos-epidemiológus) CENTER-TBI Participants and Investigators
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