CCL

Összesen 7 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM051390
Első szerző:Büki András (általános orvos)
Cím:Geriatric Traumatic Brain Injury in Hungary and Eastern Europe / András Büki, Endre Czeiter, Noémi Kovács, Krisztina Amrein, Erzsébet Ezer, János Sándor, Tamás Dóczi
Dátum:2012
ISSN:2162-4941
Megjegyzések:While the incidence of traumatic brain injury (TBI) is decreasing in the young, active population, injuries are getting more frequent among the elderly; as the geriatric population is in a constant rise and the relative cost of care is particularly high in this group of patients, the economic burden of TBI does not decline. This review is aimed to identify predisposing factors and characteristic features of geriatric brain injury, primarily focusing on the comparison between Eastern and Western European countries. While economically each of these is a high- or middle-income country, the differences in mortality and morbidity, approaches, and policies applied by health care providers are substantial. On the basis of the disappointing outcome results in Eastern Europe, one may conclude that therapeutic guidelines defined on the basis of the "Western experience" should only be applied in conjunction with a systematic reorganization of health care in Eastern Europe.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
Brain injury
Trauma
Elderly
Geriatric
Outcome prediction
Glasgow Coma Scale
IMPACT database
Epidemiology
Guideline
Eastern Europe
Hungary
Megjelenés:Current Translational Geriatrics and Experimental Gerontology Reports. - 1 : 3 (2012), p. 159-166. -
További szerzők:Czeiter Endre Kovács Noémi Amrein Krisztina Ezer Erzsébet Sándor János (1966-) (orvos-epidemiológus) Dóczi Tamás
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM051581
Első szerző:Csepregi Gyula
Cím:Súlyos koponya-agy sérültek ellátása Magyarországon, 2002-ben / Csepregi Gyula, Büki András, Futó Judit, Sándor János, Göbl Gábor, Dóczi Tamás
Dátum:2007
ISSN:0030-6002 1788-6120
Tárgyszavak:Orvostudományok Egészségtudományok magyar nyelvű folyóiratközlemény hazai lapban
súlyos koponya-agy sérülés
mortalitás
ellátási rendszer
Megjelenés:Orvosi Hetilap. - 148 : 17 (2007), p. 771-777. -
További szerzők:Büki András (1990-) (általános orvos) Futó Judit Sándor János (1966-) (orvos-epidemiológus) Göbl Gábor Dóczi Tamás
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

3.

001-es BibID:BIBFORM051564
Első szerző:Czeiter Endre
Cím:Calpain inhibition reduces axolemmal leakage in traumatic axonal injury / Endre Czeiter, András Büki, Péter Bukovics, Orsolya Farkas, József Pál, Erzsébet Kövesdi, Tamás Dóczi, János Sándor
Dátum:2009
ISSN:1420-3049
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
calpain
MDL-28170
traumatic axonal injury
traumatic brain injury
Megjelenés:Molecules [electronic resource]. - 14 : 12 (2009), p. 5115-5123. -
További szerzők:Büki András (1990-) (általános orvos) Bukovics Péter Farkas Orsolya Pál József Kövesdi Erzsébet Dóczi Tamás Sándor János (1966-) (orvos-epidemiológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

4.

001-es BibID:BIBFORM042451
035-os BibID:PMID:22435839
Első szerző:Czeiter Endre
Cím:Brain injury biomarkers may improve the predictive power of the IMPACT outcome calculator / Endre Czeiter, Stefania Mondello, Noemi Kovacs, Janos Sandor, Andrea Gabrielli, Kara Schmid, Frank Tortella, Kevin K. W. Wang, Ronald L. Hayes, Pal Barzo, Erzsebet Ezer, Tamas Doczi, Andras Buki
Dátum:2012
ISSN:0897-7151
Megjegyzések:Outcome prediction following severe traumatic brain injury (sTBI) is a widely investigated field of research. A major breakthrough is represented by the IMPACT prognostic calculator based on admission data of more than 8500 patients. A growing body of scientific evidence has shown that clinically meaningful biomarkers, including glial fibrillary acidic protein (GFAP), ubiquitin C-terminal hydrolase-L1 (UCH-L1), and αII-spectrin breakdown product (SBDP145), could also contribute to outcome prediction. The present study was initiated to assess whether the addition of biomarkers to the IMPACT prognostic calculator could improve its predictive power. Forty-five sTBI patients (GCS score8) from four different sites were investigated. We utilized the core model of the IMPACT calculator (age, GCS motor score, and reaction of pupils), and measured the level of GFAP, UCH-L1, and SBDP145 in serum and cerebrospinal fluid (CSF). The forecast and actual 6-month outcomes were compared by logistic regression analysis. The results of the core model itself, as well as serum values of GFAP and CSF levels of SBDP145, showed a significant correlation with the 6-month mortality using a univariate analysis. In the core model, the Nagelkerke R(2) value was 0.214. With multivariate analysis we were able to increase this predictive power with one additional biomarker (GFAP in CSF) to R(2)=0.476, while the application of three biomarker levels (GFAP in CSF, GFAP in serum, and SBDP145 in CSF) increased the Nagelkerke R(2) to 0.700. Our preliminary results underline the importance of biomarkers in outcome prediction, and encourage further investigation to expand the predictive power of contemporary outcome calculators and prognostic models in TBI.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
biomarkers
IMPACT calculator
outcome
prognostic models
traumatic brain injury
külföldön készült közlemény
Megjelenés:Journal of Neurotrauma. - 29 : 9 (2012), p. 1770-1778. -
További szerzők:Mondello, Stefania Kovács Noémi Sándor János (1966-) (orvos-epidemiológus) Gabrielli Andrea Schmid, Kara Tortella, Frank Wang, Kevin K. W. Hayes, Ronald L. Barzó Pál Ezer Erzsébet Dóczi Tamás Büki András (1990-) (általános orvos)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

5.

001-es BibID:BIBFORM051569
035-os BibID:PMID:18511999
Első szerző:Kasó Gábor
Cím:Comparison of CT characteristics of extravertebral cement leakages after vertebroplasty performed by different navigation and injection techniques / Gábor Kasó, Zsolt Horváth, Katalin Szenohradszky, János Sándor, Tamás Dóczi
Dátum:2008
ISSN:0001-6268
Megjegyzések:This study was intended to assess the results of post-operative CT scans in three groups of patients following percutaneous vertebroplasty (VP) using different navigation and injection methods, in an attempt to explain the radiological characteristics of extravertebral cement leakage with relation to needle placement and focused on the ventral epidural accumulation of bone cement. Furthermore, we have suggested a morphological (and functional) classification of the types of cement leakage. METHODS: Between July 2001 and February 2005, 123 percutaneous VP procedures were performed during 75 sessions in 65 patients for treatment of painful osteoporotic vertebral body compression fractures. These included:- Group I: 28 patients, 33 sessions; 50 right sided unilateral VP under fluoroscopic control with central position of the tip of the needle within the bone marrow. Group II: 27 patients, 28 sessions; 50 bilateral VP under fluoroscopic control with separate cement injections into both "hemivertebrae". Group III: 14 patients, 14 sessions; 23 bilateral VP navigated by frameless stereotaxy (neuronavigation). Needles were positioned strictly into the lateral thirds of the vertebral bodies. Leakages were classified as epidural, foraminal, intradiscal, venous paravertebral, compact extravertebral on the post-operative CT scans, and their frequency was compared in relation to the navigation method and the position of the tip of the needle. RESULTS: Group I: extravertebral cement was detected in 23 patients (82%), and in 35 (70%) of the 50 vertebrae treated (ventral epidural: 23 vertebrae = 46%; intradiscal: 12 vertebrae = 24%; venous paravertebral: 8 vertebrae = 16%; intraforaminal: 7 vertebrae = 14%; and compact extravertebral: 3 vertebrae = 6%). Group II: extravertebral cement was detected in 20 patients (74%), and in 38 (76%) of the 50 vertebrae treated (ventral epidural: 12 vertebrae = 24%; intradiscal: 12 vertebrae = 24%; venous paravertebral: 9 vertebrae = 18%; and foraminal: 1 vertebra = 2%). Group III: extravertebral cement could be detected in 10 patients (71%), and in 10 (43%) of the 23 vertebrae treated (ventral epidural: 3 vertebrae = 13%; intradiscal: 8 vertebrae = 34%; venous paravertebral: 4 vertebrae = 17%). CONCLUSION: The incidence of epidural accumulation of bone cement may be concluded to be closely correlated with the position of the tip of the needle. Centrally injected bone cement may easily invade into the basivertebral system, and the material can then be transferred via these veins toward the ventral epidural space, and result in canal compromise and/or compression of the neural elements. The results of statistical analysis (Chi-square test) revealed that injection of bone cement into the lateral third of the vertebral body significantly decreases the extent of ventral epidural leakage. Therefore, a strictly lateral injection is advised, when the tip of the needle is placed into the lateral third of the vertebral body. Frameless stereotaxy navigation improves achievement of accurate needle placement and decreases the frequency of ventral epidural leakage. It is a safe and very accurate method for positioning of the injecting needles.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
percutaneous vertebroplasty
cement leakage
frameless stereotaxy
Megjelenés:Acta Neurochirurgica. - 150 : 7 (2008), p. 677-683. -
További szerzők:Horváth Zsolt Szenohradszky Katalin Sándor János (1966-) (orvos-epidemiológus) Dóczi Tamás
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

6.

001-es BibID:BIBFORM051633
Első szerző:Sándor János (orvos-epidemiológus)
Cím:A subduralis vérzés miatt kezelt betegek halálozását befolyásoló tényezők = Risk factors for fatal outcome in subdural hemorrhage / Sándor János, Szücs Mária, Kiss István, Ember István, Csepregi Gyula, Futó Judit, Vimláti László, Pál József, Büki András, Dóczi Tamás
Dátum:2003
Tárgyszavak:Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban
subduralis vérzés
inlézményi protokollok
ellátási egyenlőtlenségek
Megjelenés:Ideggyógyászati Szemle. - 56 : 11-12 (2003), p. 386-395. -
További szerzők:Szűcs Mária Kiss István (Pécs) Ember István Csepregi Gyula Futó Judit Vimláti László Pál József Büki András (1990-) (általános orvos) Dóczi Tamás
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
Borító:

7.

001-es BibID:BIBFORM051790
035-os BibID:PMID:10214480
Első szerző:Vajda Zsolt
Cím:Transcranial Doppler-determined pulsatility index in the evaluation of endoscopic third ventriculostomy (preliminary data) / Z. Vajda, A. Büki, F. Vető, Z. Horváth, J. Sándor, T. Dóczi
Dátum:1999
ISSN:0001-6268
Megjegyzések:OBJECTIVE: Endoscopic 3rd ventriculostomy has become the method of choice in the management of occlusive hydrocephalus. The treatment is accompanied by significantly less peri-operative complications than the cerebrospinal fluid shunting procedures previously employed. Close surveillance of patients, however, is necessary to avoid the consequences of raised intracranial pressure that may develop in case of obstruction of the artificial outlet of the 3rd ventricle. The aim of this study was to confirm the value of transcranial Doppler-determined pulsatility index (PI) in the assessment of the patency of endoscopic 3rd ventriculostomy and to elucidate its usefulness in early postoperative recognition of increased intracranial pressure. METHODS: In twenty-two patients suffering from occlusive hydrocephalus, transcranial Doppler sonography (TCD) was performed before, immediately after, and five days after endoscopic fenestration of the floor of the 3rd ventricle. PI was defined with fast Fourier transformation. Mean PI values were determined in both middle cerebral arteries (MCA), over five cardiac cycles. RESULTS: In nineteen cases, PI values showed a significant decrease immediately as well as five days after the intervention as compared to the pre-operative values, and flow-sensitive MRI confirmed the patency of the fenestration in all cases. In one patient the operation failed to produce an effective diversion of cerebrospinal fluid as shown by flow-sensitive MRI, and the pulsatility index was unchanged. In two patients, a significant immediate postfenestration drop in PI was followed by a recurrence of PI to pre-operative levels without any clinical deterioration. CONCLUSIONS: Preliminary results suggest that the transcranial Doppler-determined pulsatility index is a useful non-invasive tool for the evaluation of the patency of the fenestration in the early follow-up of patients who underwent endoscopic third ventriculostomy.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
Endoscopic third ventriculostomy
occlusive hydrocephalus
pulsatility index
transcranial Doppler-sonography
Megjelenés:Acta Neurochirurgica. - 141 : 3 (1999), p. 247-250. -
További szerzők:Büki András (1990-) (általános orvos) Vető Ferenc Horváth Zsolt Sándor János (1966-) (orvos-epidemiológus) Dóczi Tamás
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Rekordok letöltése1