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001-es BibID:	BIBFORM116544
035-os BibID:	(cikkazonosító)102368 (Scopus)85166745152 (WOS)001148470600001
Első szerző:	Schilling, Danny
Cím:	The influence of alkylating agents on sulfur-sulfur bonds in per- and polysulfides / Danny Schilling, Tamás Ditrói, Uladzimir Barayeu, Eszter Petra Jurányi, Peter Nagy, Tobias P. Dick
Dátum:	2023
ISSN:	1367-5931
Megjegyzések:	Per- and polysulfides are sulfane sulfur species produced inside living cells, in organisms as diverse as bacteria, plants and humans, but their biological roles remain to be fully understood. Unfortunately, due to their reactivity, per- and polysulfides are easily altered, interconverted or lost during the processing and analysis of biological material. Thus, all current analytical methods make use of alkylating agents, to quench reactivity of hydropersulfides and hydropolysulfides and also to prevent free thiols from attacking sulfur chains in hydropolysulfides and dialkyl polysulfides. However, recent findings reveal that alkylating agents can also destroy per- and polysulfides, to varying degrees, depending on the choice of alkylating agent. Here, we discuss the challenges associated with the alkylation of per- and polysulfides, the single most important step for their preservation and detection in biological samples.
Tárgyszavak:	Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Hydropersulfides Hydropolysulfides Dialkyl polysulfides Alkylating agents
Megjelenés:	Current Opinion In Chemical Biology. - 76 (2023), p. 1-8. -
További szerzők:	Ditrói Tamás (1989-) (vegyész) Barayeu, Uladzimir Jurányi Eszter Petra Nagy Péter (1976-) (vegyész) Dick, Tobias P.
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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