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001-es BibID:	BIBFORM120116
035-os BibID:	(Scopus)85170690960 (WoS)001066356100001
Első szerző:	Chatterjee, Tulika
Cím:	Type 1 diabetes, COVID-19 vaccines and short-term safety : subgroup analysis from the global COVAD study / Tulika Chatterjee, Naveen Ravichandran, Narmadha Nair, Abraham Edgar Gracia-Ramos, Bhupen Barman, Parikshit Sen, Mrudula Joshi, Sreoshy Saha, Arvind Nune, Arun Kumar R. Pande, Tsvetelina Velikova, Ioannis Parodis, Ai Lyn Tan, Samuel Katsuyuki Shinjo, Hiya Boro, Vikas Agarwal, Rohit Aggarwal, Latika Gupta, COVAD Study Group
Dátum:	2023
ISSN:	2040-1116 2040-1124
Megjegyzések:	Aims/introduction: Coronavirus disease 2019 (COVID-19) vaccinations have been proven to be generally safe in healthy populations. However, the data on vaccine safety in patients with type 1 diabetes are scarce. This study aimed to evaluate the frequency and severity of short-term (<7-day) adverse vaccination events (AEs) and their risk factors among type 1 diabetes patients. Materials and methods: This study analyzed data from the COVID-19 vaccination in Autoimmune Diseases (COVAD) survey database (May to December 2021; 110 collaborators, 94 countries), comparing <7-day COVID-19 vaccine AE among type 1 diabetes patients and healthy controls (HCs). Descriptive statistics; propensity score matching (1:4) using the variables age, sex and ethnicity; and multivariate analyses were carried out. Results: This study analyzed 5,480 completed survey responses. Of all responses, 5,408 were HCs, 72 were type 1 diabetes patients (43 females, 48.0% white European ancestry) and Pfizer was the most administered vaccine (39%). A total of 4,052 (73.9%) respondents had received two vaccine doses. Patients with type 1 diabetes had a comparable risk of injection site pain, minor and major vaccine AEs, as well as associated hospitalizations to HCs. However, type 1 diabetes patients had a higher risk of severe rashes (3% vs 0.4%, OR 8.0, 95% confidence interval 1.7-36), P = 0.007), although reassuringly, these were rare (n = 2 among type 1 diabetes patients). Conclusions: COVID-19 vaccination was safe and well tolerated in patients with type 1 diabetes with similar AE profiles compared with HCs, although severe rashes were more common in type 1 diabetes patients.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk COVID-19 Type-1 diabetes mellitus Vaccine
Megjelenés:	Journal of Diabetes Investigation. - 15 : 1 (2023), p. 131-138. -
További szerzők:	Ravichandran, Naveen Nair, Narmadha Gracia-Ramos, Abraham Edgar Barman, Bhupen Sen, Parikshit Joshi, Mrudula Saha, Sreoshy Nune, Arvind Pande, Arunkumar R. Velikova, Tsvetelina Parodis, Ioannis Tan, Ai Lyn Shinjo, Samuel Katsuyuki Boro, Hiya Agarwal, Vikas Aggarwal, Rohit Gupta, Latika Nagy-Vincze Melinda (1985-) (orvos) COVAD Study Group
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