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1.
001-es BibID:
BIBFORM117879
035-os BibID:
(scopus)85162972096 (wos)001014747300001
Első szerző:
Doskaliuk, Bohdana
Cím:
Long-term safety of COVID vaccination in individuals with idiopathic inflammatory myopathies : results from the COVAD study / Doskaliuk Bohdana, Ravichandran Naveen, Sen Parikshit, Day Jessica, Joshi Mrudula, Nune Arvind, Nikiphorou Elena, Saha Sreoshy, Tan Ai Lyn, Shinjo Samuel Katsuyuki, Ziade Nelly, Velikova Tsvetelina, Milchert Marcin, Jagtap Kshitij, Parodis Ioannis, Gracia-Ramos Abraham Edgar, Cavagna Lorenzo, Kuwana Masataka, Knitza Johannes, Chen Yi Ming, Makol Ashima, Agarwal Vishwesh, Patel Aarat, Pauling John D., Wincup Chris, Barman Bhupen, Tehozol Erick Adrian Zamora, Serrano Jorge Rojas, La Torre Ignacio García-De, Colunga-Pedraza Iris J., Merayo-Chalico Javier, Chibuzo Okwara Celestine, Katchamart Wanruchada, Goo Phonpen Akarawatcharangura, Shumnalieva Russka, Hoff Leonardo Santos, Kibbi Lina El, Halabi Hussein, Vaidya Binit, Shaharir Syahrul Sazliyana, Hasan A. T. M. Tanveer, Dey Dzifa, Gutiérrez Carlos Enrique Toro, Caballero-Uribe Carlo V., Lilleker James B., Salim Babur, Gheita Tamer, Chatterjee Tulika, Distler Oliver, Saavedra Miguel A., COVAD study group, Chinoy Hector, Agarwal Vikas, Aggarwal Rohit, Gupta Latika
Dátum:
2023
ISSN:
0172-8172 1437-160X
Megjegyzések:
Limited evidence on long-term COVID-19 vaccine safety in patients with idiopathic inflammatory myopathies (IIMs) continues to contribute to vaccine hesitancy. We studied delayed-onset vaccine adverse events (AEs) in patients with IIMs, other systemic autoimmune and inflammatory disorders (SAIDs), and healthy controls (HCs), using data from the second COVID-19 Vaccination in Autoimmune Diseases (COVAD) study. A validated self-reporting e-survey was circulated by the COVAD study group (157 collaborators, 106 countries) from Feb-June 2022. We collected data on demographics, comorbidities, IIM/SAID details, COVID-19 history, and vaccination details. Delayed-onset (> 7 day) AEs were analyzed using regression models. A total of 15165 respondents undertook the survey, of whom 8759 responses from vaccinated individuals [median age 46 (35-58) years, 74.4% females, 45.4% Caucasians] were analyzed. Of these, 1390 (15.9%) had IIMs, 50.6% other SAIDs, and 33.5% HCs. Among IIMs, 16.3% and 10.2% patients reported minor and major AEs, respectively, and 0.72% (n = 10) required hospitalization. Notably patients with IIMs experienced fewer minor AEs than other SAIDs, though rashes were expectedly more than HCs [OR 4.0; 95% CI 2.2-7.0, p < 0.001]. IIM patients with active disease, overlap myositis, autoimmune comorbidities, and ChadOx1 nCOV-19 (Oxford/AstraZeneca) recipients reported AEs more often, while those with inclusion body myositis, and BNT162b2 (Pfizer) recipients reported fewer AEs. Vaccination is reassuringly safe in individuals with IIMs, with AEs, hospitalizations comparable to SAIDs, and largely limited to those with autoimmune multimorbidity and active disease. These observations may inform guidelines to identify high-risk patients warranting close monitoring in the post-vaccination period.
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Adverse event
Autoimmunity
COVID-19
Myositis
Surveys and questionnaires
Vaccination
Megjelenés:
Rheumatology International. - 43 : 9 (2023), p. 1651-1664. -
További szerzők:
Ravichandran, Naveen
Sen, Parikshit
Day, Jessica
Joshi, Mrudula
Nune, Arvind
Nikiphorou, Elena (reumatológus)
Saha, Sreoshy
Tan, Ai Lyn
Shinjo, Samuel Katsuyuki
Ziade, Nelly
Velikova, Tsvetelina
Milchert, Marcin
Jagtap, Kshitij
Parodis, Ioannis
Gracia-Ramos, Abraham Edgar
Cavagna, Lorenzo
Kuwana, Masataka
Knitza, Johannes
Chen, Yi Ming
Makol, Ashima
Agarwal, Vishwesh
Patel, Aarat
Pauling, John D.
Wincup, Chris
Barman, Bhupen
Tehozol, Erick Adrian Zamora
Serrano, Jorge Rojas
La Torre, Ignacio García-De
Colunga-Pedraza, Iris J.
Merayo-Chalico, Javier
Chibuzo, Okwara Celestine
Katchamart, Wanruchada
Akawatcharangura Goo, Phonpen
Shumnalieva, Russka
Hoff, Leonardo Santos
Kibbi, Lina El
Halabi, Hussein
Vaidya, Binit
Shaharir, Syahrul Sazliyana
Hasan, A. T. M. Tanveer
Dey, Dzifa
Gutiérrez, Carlos-Enrique Toro
Caballero-Uribe, Carlo Vinicio
Lilleker, James B.
Salim, Babur
Gheita, Tamer A.
Chatterjee, Tulika
Distler, Oliver
Saavedra, Miguel A.
Chinoy, Hector
Agarwal, Vikas
Aggarwal, Rohit
Gupta, Latika
Griger Zoltán (1979-) (belgyógyász, allergológus és klinikai immunológus, reumatológus)
Nagy-Vincze Melinda (1985-) (orvos)
COVAD Study Group
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
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Saját polcon:
2.
001-es BibID:
BIBFORM120113
Első szerző:
Naveen, R.
Cím:
Safety and tolerance of vaccines against SARS-CoV-2 infection in systemic lupus erythematosus : results from the COVAD study / Naveen R., Nikiphorou Elena, Joshi Mrudula, Sen Parikshit, Lindblom Julius, Agarwal Vishwesh, Lilleker James B., Tan Ai Lyn, Salim Babur, Ziade Nelly, Velikova Tsvetelina, Gracia-Ramos Abraham Edgar, Kuwana Masataka, Day Jessica, Makol Ashima, Distler Oliver, Chinoy Hector, Traboco Lisa S., Wibowo Suryo Anggoro Kusumo, Tehozol Erick Adrian Zamora, Serrano Jorge Rojas, García-De La Torre Ignacio, COVAD Study Group, Aggarwal Rohit, Gupta Latika, Agarwal Vikas, Parodis Ioannis
Dátum:
2023
ISSN:
1462-0324 1462-0332
Megjegyzések:
Objective: To determine COVID-19 vaccine-related adverse events (AEs) in the seven-day post-vaccination period in patients with SLE vs autoimmune rheumatic diseases (AIRDs), non-rheumatic autoimmune diseases (nrAIDs), and healthy controls (HC). Methods: Data were captured through the COVID-19 Vaccination in Autoimmune Diseases (COVAD) questionnaire (March-December 2021). Multivariable regression models accounted for age, gender, ethnicity, vaccine type and background treatment. Results: Among 9462 complete respondents, 583 (6.2%) were SLE patients (mean age: 40.1 years; 94.5% females; 40.5% Asian; 42.9% Pfizer-recipients). Minor AEs were reported by 83.0% of SLE patients, major by 2.6%, hospitalization by 0.2%. AE and hospitalization frequencies were similar between patients with active and inactive SLE. Rashes were more frequent in SLE patients vs HC (OR; 95% CI: 1.2; 1.0, 1.5), chills less frequent in SLE vs AIRDs (0.6; 0.4, 0.8) and nrAIDs (0.5; 0.3, 0.8), and fatigue less frequent in SLE vs nrAIDs (0.6; 0.4, 0.9). Pfizer-recipients reported higher overall AE (2.2; 1.1, 4.2) and injection site pain (2.9; 1.6, 5.0) frequencies than recipients of other vaccines, Oxford/AstraZeneca-recipients more body ache, fever, chills (OR: 2.5, 3.0), Moderna-recipients more body ache, fever, chills, rashes (OR: 2.6, 4.3). Hospitalization frequencies were similar across vaccine types. AE frequencies were similar across treatment groups, although chills were less frequent in antimalarial users vs non-users (0.5; 0.3, 0.9). Conclusion: While COVID-19 vaccination-related AEs were reported by four-fifths of SLE patients, those were mostly minor and comparable to AEs reported by healthy individuals, providing reassurance regarding COVID-19 vaccination safety in SLE.
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
COVID-19
adverse events
rheumatology
systemic lupus erythematosus
vaccine
Megjelenés:
Rheumatology. - 62 : 7 (2023), p. 2453-2463. -
További szerzők:
Nikiphorou, Elena (reumatológus)
Joshi, Mrudula
Sen, Parikshit
Lindblom, Julius
Agarwal, Vishwesh
Lilleker, James B.
Tan, Ai Lyn
Salim, Babur
Ziade, Nelly
Velikova, Tsvetelina
Gracia-Ramos, Abraham Edgar
Kuwana, Masataka
Day, Jessica
Makol, Ashima
Distler, Oliver
Chinoy, Hector
Traboco, Lisa S.
Wibowo, Suryo Anggoro Kusumo
Tehozol, Erick Adrian Zamora
Serrano, Jorge Rojas
García-De La Torre, Ignacio
Aggarwal, Rohit
Gupta, Latika
Agarwal, Vikas
Parodis, Ioannis
Nagy-Vincze Melinda (1985-) (orvos)
COVAD Study Group
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
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