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1.
001-es BibID:
BIBFORM120116
035-os BibID:
(Scopus)85170690960 (WoS)001066356100001
Első szerző:
Chatterjee, Tulika
Cím:
Type 1 diabetes, COVID-19 vaccines and short-term safety : subgroup analysis from the global COVAD study / Tulika Chatterjee, Naveen Ravichandran, Narmadha Nair, Abraham Edgar Gracia-Ramos, Bhupen Barman, Parikshit Sen, Mrudula Joshi, Sreoshy Saha, Arvind Nune, Arun Kumar R. Pande, Tsvetelina Velikova, Ioannis Parodis, Ai Lyn Tan, Samuel Katsuyuki Shinjo, Hiya Boro, Vikas Agarwal, Rohit Aggarwal, Latika Gupta, COVAD Study Group
Dátum:
2023
ISSN:
2040-1116 2040-1124
Megjegyzések:
Aims/introduction: Coronavirus disease 2019 (COVID-19) vaccinations have been proven to be generally safe in healthy populations. However, the data on vaccine safety in patients with type 1 diabetes are scarce. This study aimed to evaluate the frequency and severity of short-term (<7-day) adverse vaccination events (AEs) and their risk factors among type 1 diabetes patients. Materials and methods: This study analyzed data from the COVID-19 vaccination in Autoimmune Diseases (COVAD) survey database (May to December 2021; 110 collaborators, 94 countries), comparing <7-day COVID-19 vaccine AE among type 1 diabetes patients and healthy controls (HCs). Descriptive statistics; propensity score matching (1:4) using the variables age, sex and ethnicity; and multivariate analyses were carried out. Results: This study analyzed 5,480 completed survey responses. Of all responses, 5,408 were HCs, 72 were type 1 diabetes patients (43 females, 48.0% white European ancestry) and Pfizer was the most administered vaccine (39%). A total of 4,052 (73.9%) respondents had received two vaccine doses. Patients with type 1 diabetes had a comparable risk of injection site pain, minor and major vaccine AEs, as well as associated hospitalizations to HCs. However, type 1 diabetes patients had a higher risk of severe rashes (3% vs 0.4%, OR 8.0, 95% confidence interval 1.7-36), P = 0.007), although reassuringly, these were rare (n = 2 among type 1 diabetes patients). Conclusions: COVID-19 vaccination was safe and well tolerated in patients with type 1 diabetes with similar AE profiles compared with HCs, although severe rashes were more common in type 1 diabetes patients.
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
COVID-19
Type-1 diabetes mellitus
Vaccine
Megjelenés:
Journal of Diabetes Investigation. - 15 : 1 (2023), p. 131-138. -
További szerzők:
Ravichandran, Naveen
Nair, Narmadha
Gracia-Ramos, Abraham Edgar
Barman, Bhupen
Sen, Parikshit
Joshi, Mrudula
Saha, Sreoshy
Nune, Arvind
Pande, Arunkumar R.
Velikova, Tsvetelina
Parodis, Ioannis
Tan, Ai Lyn
Shinjo, Samuel Katsuyuki
Boro, Hiya
Agarwal, Vikas
Aggarwal, Rohit
Gupta, Latika
Nagy-Vincze Melinda (1985-) (orvos)
COVAD Study Group
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
2.
001-es BibID:
BIBFORM117880
035-os BibID:
(WOS)001116143800001 (Scopus)85181481512
Első szerző:
Panchawagh, Suhrud
Cím:
COVID-19 breakthrough infections in type 1 diabetes mellitus : a cross-sectional study by the COVID-19 Vaccination in Autoimmune Diseases (COVAD) Group / Panchawagh Suhrud, Ravichandran Naveen, Barman Bhupen, Nune Arvind, Javaid Mahnoor, Gracia-Ramos Abraham Edgar, Day Jessica, Joshi Mrudula, Kuwana Masataka, Saha Sreoshy, Pande Arunkumar R., Caballero-Uribe Carlo Vinicio, Velikova Tsvetelina, Parodis Ioannis, Knitza Johannes, Kadam Esha, Tan Ai Lyn, Shinjo Samuel Katsuyuki, Boro Hiya, COVAD Study Group, Aggarwal Rohit, Agarwal Vikas, Chatterjee Tulika, Gupta Latika
Dátum:
2023
ISSN:
0172-8172 1437-160X
Megjegyzések:
To investigate the frequency, profile, and severity of COVID-19 breakthrough infections (BI) in patients with type I diabetes mellitus (T1DM) compared to healthy controls (HC) after vaccination. The second COVID-19 Vaccination in Autoimmune Diseases (COVAD-2) survey is a multinational cross-sectional electronic survey which has collected data on patients suffering from various autoimmune diseases including T1DM. We performed a subgroup analysis on this cohort to investigate COVID-19 BI characteristics in patients with T1DM. Logistic regression with propensity score matching analysis was performed. A total of 9595 individuals were included in the analysis, with 100 patients having T1DM. Among the fully vaccinated cohort, 16 (16%) T1DM patients had one BI and 2 (2%) had two BIs. No morbidities or deaths were reported, except for one patient who required hospitalization with oxygen without admission to intensive care. The frequency, clinical features, and severity of BIs were not significantly different between T1DM patients and HCs after adjustment for confounding factors. Our study did not show any statistically significant differences in the frequency, symptoms, duration, or critical care requirements between T1DM and HCs after COVID-19 vaccination. Further research is needed to identify factors associated with inadequate vaccine response in patients with BIs, especially in patients with autoimmune diseases.
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Breakthrough infections
COVID-19
Survey
Type 1 diabetes mellitus
Vaccine
Megjelenés:
Rheumatology International. - 44 : 1 (2023), p. 73-80. -
További szerzők:
Ravichandran, Naveen
Barman, Bhupen
Nune, Arvind
Javaid, Mahnoor
Gracia-Ramos, Abraham Edgar
Day, Jessica
Joshi, Mrudula
Kuwana, Masataka
Saha, Sreoshy
Pande, Arunkumar R.
Caballero-Uribe, Carlo Vinicio
Velikova, Tsvetelina
Parodis, Ioannis
Knitza, Johannes
Kadam, Esha
Tan, Ai Lyn
Shinjo, Samuel Katsuyuki
Boro, Hiya
Aggarwal, Rohit
Agarwal, Vikas
Chatterjee, Tulika
Gupta, Latika
Griger Zoltán (1979-) (belgyógyász, allergológus és klinikai immunológus, reumatológus)
Nagy-Vincze Melinda (1985-) (orvos)
COVAD Study Group
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
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