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001-es BibID:BIBFORM079831
Első szerző:Fekete István (neurológus, pszichiáter)
Cím:Effect of acute stroke on heart function / I. Fekete, N. Deregi, J. Aranyosi, K. Fekete, L. Csiba
Dátum:2010
Megjegyzések:Background: There are contradictory data on how brain hemispheric localization/side influences the function of the heart. Our aim was to study the pathologic cardiological abnormalities in acute stroke patients without coronary heart disease or rhythm disturbances in the anamnesis. Methods: Between 1st of March, 2009 and 30th of September, 2009 at the Neurointensive Care Unit we monitorized 91 acute stroke patients' parameters continuously for 24-36 hours: pulse, systolic, diastolic, mean blood pressure, 12 lead ECG. We were interested in the correlation of the above mentioned parameters and age, side and size of the cerebral lesion (by CT/MRI), type of stroke, mortality. Exclusion criteria were: fever, severe hyperglycemia, cardiac failure, myocardial infarct, pulmonary disorders, obstructive sleep apnoe, drug or metabolic caused rhythm disturbances, beta blocker usage. Results: The average age was 62,3?14,6 years. The left hemisphere was affected in 45%, the right in 38,5%, both hemispheres in 3,3%, and 13,2% suffered from VB syndrome. Ischemic stroke was in 74,7%, hemorrhage 14,3%, SAH 3,3%, TIA 7,7%. In the group where no heart disorder was known at admission, altogether 18% had repolarization abnormalities (10 patients had ST depression, 7 ST elevation). In addition, especially during the night, by 33% of the patients supraventricular (SVES) and ventricular extrasystoles (VES) were detected. 35% of patients had tachycardy and 23% bradycardy, both were significantly higher in the right sided lesions (p<0.05). VES was more frequent in left hemispherical lesions and VB syndrome (p<0.05). Less than 90 mmHg systolic pressure could be detected in 27% of patients, this was remarkable at dawn. Nine patients died, in 2 patients fatal rhythm disturbance caused death. Conclusion: Both sided hemispheric lesions and VB syndromes can cause cardiological and ECG abnormalities. Intensive monitoring is essential in acute stroke at least for 36 hours.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
Megjelenés:Cerebrovascular Diseases. - 29 : Suppl. 2 (2010), p. 157. -
További szerzők:Deregi N. Aranyosi János (1963-) (szülész-nőgyógyász) ifj. Fekete Klára (1978-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter)
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2.

001-es BibID:BIBFORM079825
Első szerző:Fekete Klára (neurológus)
Cím:Experiences with intravenous (IV) and intraarterial (IA) thrombolysis in Debrecen, Hungary, focused on glucose level at admission and patients over 80 / K. Fekete, D. Bereczki, L. Csiba, I. Fekete
Dátum:2010
ISSN:1015-9770
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
stroke
Megjelenés:Cerebrovascular Diseases. - 29 : 2 (2010), p. 1-361. -
További szerzők:Bereczki Dániel (1960-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
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3.

001-es BibID:BIBFORM079826
Első szerző:Fekete Klára (neurológus)
Cím:Alcohol consumption and smoking are associated with higher 30-day case fatality after stroke in the mures-uzhgorod-debrecen (mud) database / K. E. Fekete, S. Szatmári, I. Szőcs, C. Szekeres, J. Szász, L. Mihálka, V. Smolanka, L. Csiba, D. Bereczki
Dátum:2008
ISSN:1015-9770
Megjegyzések:Abstract Introduction: Age, alcohol consumption, smoking are important risk factors of stroke. After stroke most of the patients suffer from different grade of disability. Methods: In this work the risk factors, mentioned above, the disability and the 30 day case fatality was investigated by analyzing the data of 1047 patients from the MUD database between the 1 st of October 1999 and 30th of September 2000. (The distribution of the patients in the database is the following: 554 patients in Debrecen, 260 patients in Targu Mures and 233 in Uzhgorod). Results: The distribution of stroke concerning the genders by our database is the following: 42,5% female, 57,5 % male. Before discharge 222 patients (22,1%) died. By 172 of the patients (16,4%) occurred stroke in the familial-history. The ratio of the age was found more unfavorable by males: between 30 and 60 years the frequency of stroke was twice as high as by females (on the average by 30,75% of women and 69,26% of men suffer stroke).The ratio is very similar by cerebral bleeding not only ischemia. 249 of total stroke patients admitted alcohol consumption (23,8%), 551 did not (52,6%) (28,6%is unknown). The 30 day mortality rate was 25,3% between the patients admitting alcohol consumption, and only 9,3% between those who did not. In total 339 patients suffered cerebral bleeding ( 32,4%), which is higher then the literary dates. No difference was found between the 3 examination places. The ratio of death in the group of alcohol consumers and alcohol-non-consumer was equally prominently high without any difference. In our database 25,09% of the patients smoked. The excess of disability at dismission was analyzed by 825 patients with the following results: 153 patients (18,5%) needed permanent care, 182 (22%) patients needed help by every-day-life, 230 (27,5%) patients could live a self-sufficient life with residual signs, and 260 (31,5%) had no neurological sign. Results and conclusion: The analysis of the MUD database emphasizes the medical education of the population in health policy.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
stroke
Megjelenés:Cerebrovascular Diseases. - 25 : 2 (2008), p. 71. -
További szerzők:Szatmári Szabolcs (1960-) (neurológus) Szőcs Ildikó (1970-) (orvos) Szekeres Csilla Cecília (1980-) (orvos) Szász József (1960-) (neurológus) Mihálka László (1950-) (neurológus) Smolanka, Volodymyr I. (1950-) (orvos) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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4.

001-es BibID:BIBFORM069439
Első szerző:Fekete Klára (neurológus)
Cím:Outcome of Repeated Thrombolysis in Debrecen Thrombolysis Database / Klára Fekete, Sándor Márton, László Csiba, István Fekete
Dátum:2017
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 26 : 1 (2017), p. 132-138. -
További szerzők:Márton Sándor (szociológus) Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
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5.

001-es BibID:BIBFORM062617
Első szerző:Fekete Klára (neurológus)
Cím:Predictors of Long-term Outcome after Intravenous or Intra-arterial Recombinant Tissue Plasminogen Activator Treatment in the Eastern Hungarian Thrombolysis Database / Klára Fekete, Sándor Márton, Judit Tóth, László Csiba, István Fekete, Dániel Bereczki
Dátum:2015
ISSN:1052-3057 1532-8511
Megjegyzések:Background: This prospective single-center study aimed to identify features determininglong-term outcome after thrombolysis in a Central European stroke population.Methods: Between 1 January, 2004, and 31 December, 2010, 415 patients weretreated with recombinant tissue plasminogen activator at the Department ofNeurology, University of Debrecen. Stroke severity by the National Institute ofHealth Stroke Scale score (NIHSSS) and imaging findings by the Alberta Stroke ProgrammeEarly Computed Tomography score (ASPECTS) were evaluated on admissionand 1 day later. The modified Rankin Scale (mRS) at 3 months and case fatalityat 1 year were evaluated. Independent predictors of outcome were identified bymultivariate testing. Results: Data of 369 patients were analyzed. Median NIHSSSwas 12 (interquartile range [IQR], 8-17) on admission and 10 (IQR, 5-16) at 24 hours.Arterial occlusion was found in 55%. Symptomatic intracerebral hemorrhage (SICH)was detected in 3.8%. Outcome was significantly worse, and SICH was morefrequent in intra-arterially treated patients. At 3 months, one third of the patientswere independent (mRS #2), and 23% were dead. At 1 year 2 of 3 patients were alive.Significant independent predictors of disability at 3 months were 24-hour NIHSSS,admission ASPECTS, admission glucose level, and treatment modality. Only the24-hour NIHSSS was a significant predictor of case fatality at 1 year. Conclusions:Although short-term outcome was similar, the 3-month and 1-year outcomes wereworse than data from previous reports. A more efficient health care program shouldbe implemented after stroke to maintain the favorable effect of thrombolysis in thelong term.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Ischemic stroke
thrombolysis
predictors
outcome
Megjelenés:Journal Of Stroke And Cerebrovascular Diseases. - 24 : 1 (2015), p. 117-124. -
További szerzők:Márton Sándor (szociológus) Tóth Judit Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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6.

001-es BibID:BIBFORM049525
Első szerző:Fekete Klára (neurológus)
Cím:Prestroke Alcohol Consumption and Smoking Are Not Associated with Stroke Severity, Disability at Discharge, and Case Fatality / Klára Fekete, Szabolcs Szatmári, Ildikó Szőcs, Csilla Szekeres, József Szász, László Mihálka, Volodymyr Smolanka, László Kardos, László Csiba, Dániel Bereczki
Dátum:2014
Megjegyzések:Background: Heavy alcohol consumption and smoking are known risk factors for stroke but their influence on stroke severity and outcome may also be important. We tested if alcohol consumption and smoking relate to initial stroke severity, disability at discharge from hospital and outcome at 30 days and at 1 year in 1049 patients of the Mures-Uzhgorod-Debrecen database. Methods: Initial stroke severity was scored by the NIH stroke scale. Case fatality and the modified outcome scale of the 1st International Stroke Trial were used to assess outcome. We used multiple regression analysis.Results: Before their stroke, 24.5% were smokers and 24.7 % admitted regular alcohol consumption. Neither smoking nor alcohol consumption status were associated with initial stroke severity. Case fatality at discharge, at 30 days and at 1 year were 12.2%, 16.9% and 28.3%, respectively. Initial stroke severity, hemorrhagic subtype, and age in men over 60 years were strong predictors of outcome. We did not find significant difference among alcohol consumers and non-consumers in 30-day and in one year case fatality in all stroke patients and in ischemic stroke patients. In hemorrhagic stroke, there was a non-significant tendency for higher case fatality among alcohol-consumers (39.5% vs. 26.4%, p>0.2 at 30 days and 48.8% vs. 35.8%, p>0.2 at 1 year). Smoking did not influence significantly the outcome at 30-days and at one-year.Conclusion: despite being risk factors, pre-stroke smoking and alcohol consumption do not have a significant influence on stroke severity and on short- and long- term outcome.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Alcohol, smoking and stroke severity
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 23 : 1 (2014), p. e31-e37. -
További szerzők:Szatmári Szabolcs (1960-) (neurológus) Szőcs Ildikó (1970-) (orvos) Szekeres Csilla Cecília (1980-) (orvos) Szász József (1960-) (neurológus) Mihálka László (1950-) (neurológus) Smolanka, Volodymyr I. (1950-) (orvos) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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DOI
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