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1.

001-es BibID:BIBFORM079842
Első szerző:Fekete István (neurológus, pszichiáter)
Cím:Correlation of serum level of antiepileptic drugs (AEDS) and compliance in patients with epilepsy in the East-Hungarian epilepsy database / I. Fekete, S. Puskas, E. Csoto , K. Fekete, E. Barna , B. Vamosi, L. Horvath
Dátum:2007
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
epilepsy
Megjelenés:European Journal of Neurology. - 14 : Suppl. 1 (2007), p. 214. -
További szerzők:Puskás Szilvia (1979-) (neurológus) Feketéné Csótó Edit (gyógyszerész) Fekete Klára (1978-) (neurológus) Barna Edit Vámosi Bertalan Horváth László (1973-) (gyógyszerész)
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2.

001-es BibID:BIBFORM079823
Első szerző:Fekete Klára (neurológus)
Cím:A novel form of distal hereditary motor neuropathy type II (distal HMN II) / K. Fekete, A. Schirmacher, E. De Vriendt, V. Timmerman, G. Kuhlenbäumer
Dátum:2005
Megjegyzések:Introduction: We investigated a German family with typical adult onset distal HMN II. The family contains 28 members, of whom 12 are certainly a?ected by the disease. Methods: Mutations in the coding regions of the two known genes for distal HMN (HSP22 and HSP27) were excluded by direct DNA sequencing. Other genes, causing diseases with similar phenotypes (see results) were excluded by linkage analysis using short-tandem-repeat (STR) markers within or very close to the genes. In addition, we started a genome-wide linkage screen using the ABI-Prism Linkage Mapping Set -10 containing 382 autosomal STR markers. Two point LOD scores were calculated using the program MLINK from the FASTLINK program package. Results: We did not ?nd any disease-associated mutations in the HSP22 or HSP27 genes. The candidate genes glycyl-tRNA synthetase(GARS),BerardinelliSeipCongenitalLipodystrophy2gene (BSCL2) and dynactin 1 (DCTN1) could be excluded by linkage analysis. 60% of the genome-wide linkage screen is completed, but so far, we did not ?nd any region with conclusive LOD scores. Conclusion: We excluded more than 60% of the genome and the most important known genes causing distal HMN and related phenotypes by linkage and mutation analysis. It is, therefore, probably that the family with HMN examined in this study represents a novel genetic entity.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
Hereditary neuropathy
Megjelenés:European Journal of Neurology. - 12 : Suppl. 2 (2005), p. 118. -
További szerzők:Schirmacher, Anja De Vriendt, E. Timmerman, Vincent Kuhlenbäumer, Gregor
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3.

001-es BibID:BIBFORM079822
Első szerző:Fekete Klára (neurológus)
Cím:Effectiveness and outcome of intravenous (IV) and intra-arterial (IA) thrombolysis in the Eastern Hungarian Stroke Center / K. Fekete, I. Fekete, D. Bereczki, T. Magyar, L. Olah, T. Csepany, L. Csiba
Dátum:2009
ISSN:1351-5101
Megjegyzések:Introduction: IV and IA thrombolysis is an effective treatment in acute ischemic stroke. Effectiveness and side effects were tested in the database. Methods: We treated 208 patients with IV/IA (145/63 pts) rt-PA after onset of ischemic stroke. After urgent CT, CTA we administered 0.9 mg/kg rt-PA according to the protocol. At local thrombolysis after 5 mg rt-PA bolus, 1 mg/min infusionwasadministered.GCS,NIHSSwereexaminedon the admission and after 7 days, mRS after 3 months. Risk factors and time window of stroke were estimated, too. Results: 64% of patients were male and 36% female.Time window was within 120min by 28% of patients, 180min 44%, 4.5h 17% and more than 270min 11% (for IA thrombolysis)afterstrokeonset.Averageagewas66.5?13.9 and 67.3?14.7 years.The most important risk factors were: hypertension (68.5%), atrial fibrillation (17%), other heart disorders(20%),smoking18.5%),diabetesmellitus(16%), hypercholesterolemia(19%),previousstrokeorTIA(16%). The average of NIHSS before thrombolysis was 14 (2-25), after 24 hours 11 (0-25). Hemorrhagic transformation was 13% after IA, 4.4% after IV administration of rt-PA. Intracerebral haemorrhage was recognized in 17.6% after IA,4.4%IV .Mortalitywas3%within24hours,21%within 3 months (IA: 27.9%, IV:13%). Large artery re-opening after IA thrombolysis was 46%. The proportion of independent patients was 36.4% (mRS) at 3 months. Conclusion: Beside IV thrombolysis IA administration of rt-PA is effective in acute stroke, but ICH and hemorrhagic transformation rate is more frequent
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
thrombolysis
Megjelenés:European Journal of Neurology. - 16 : Suppl. 3 (2009), p. 393. -
További szerzők:Fekete István (1951-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus) Magyar T. Oláh László (1967-) (neurológus) Csépány Tünde (1956-) (neurológus, pszichiáter) Csiba László (1952-) (neurológus, pszichiáter)
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4.

001-es BibID:BIBFORM049534
Első szerző:Kõrv, Janika
Cím:Benefit of thrombolysis for stroke is maintained around the clock : results from the SITS-EAST Registry / J. Kõrv, R. Vibo, P. Kadlecová, A. Kobayashi, A. Czlonkowska, M. Brozman, V. Švigelj, L. Csiba, K. Fekete, V. Demarin, A. Vilionskis, D. Jatuzis, Y. Krespi, N. Ahmed, R. Mikulík, the Safe Implementation of Treatments in Stroke - East (SITS-EAST) Registry Investigators
Dátum:2014
ISSN:1351-5101
Megjegyzések:Background and purpose: The outcome of thrombolysis for early morning and sleeptime strokes may be worse because of uncertainty of stroke onset time or differencesin logistics. The aim of the study was to analyze if stroke outcome after intravenousthrombolysis differs depending on time of day when the stroke occurs.Methods: The data collected in the Safe Implementation of Treatments in Stroke Eastern Europe (SITS-EAST) Registry between September 2000 and December2011 were used. Strokes were categorized as night-time 00:00?07:59, day-time08:00?15:59 and evening-time 16:00?23:59 and were compared in terms of severaloutcome measures. All results were adjusted for baseline differences.Results: A total of 8878 patients were enrolled: 18% had night-time, 54% day-timeand 28% evening-time strokes. Onset-to-treatment time in patients with night-timestrokes was 10 min longer than in day-time and evening-time strokes (P < 0.001).Symptomatic intracerebral hemorrhage by ECASS II definition occurred in 5.6%,5.6% and 5.3% (adjusted P = 0.41) of the night-time, day-time and evening-timestroke patients, respectively; by SITS definition it occurred in 2.5%, 1.9% and 1.3%(adjusted P = 0.013) and by NINDS definition in 7.8%, 7.6% and 7.5% (adjustedP = 0.74). Patients with night-time, day-time and evening-time strokes achievedmodified Rankin Scale score 0?1 in 33%, 31%, 31% (adjusted P = 0.34) and 0?2 in52%, 51%, 50% (adjusted P = 0.23), and 13%, 15%, 16% respectively of patientsdied (adjusted P = 0.17) by 3 months.Conclusions: The time when stroke occurs (day versus evening versus night) doesnot affect the outcome after thrombolysis despite the fact that patients with nighttimestrokes have worse time management.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
circadian variation
mRS
NIHSS
outcome
SITS
stroke
symptomatic intracerebral haemorrhage
trhombolysis
Megjelenés:European Journal of Neurology 21 : 1 (2014), p. 112-117. -
További szerzők:Vibo, R. Kadlecova, Pavla Kobayashi, Anna Czlonkowska, A. Brozman, Miroslav Švigelj, Victor Csiba László (1952-) (neurológus, pszichiáter) Fekete Klára (1978-) (neurológus) Demarin, Vida Vilionskis, Aleksandras Jatuzis, Dalius Krespi, Yakup Ahmed, Niaz Mikulík, Robert The Safe Implementation of Treatments in Stroke - East (SITS-EAST) Registry Investigators
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5.

001-es BibID:BIBFORM079835
Első szerző:Szőcs Ildikó (orvos)
Cím:Mannitol treatment in stroke patients in a prospective, observational study performed during 1 year in targu-mures emergency hospital, Romania / I. Szocs, K. Orbán-Kis, J. A. Szasz, Z. Bajko, K. Fekete, Sz. Szatmari
Dátum:2007
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
stroke
Megjelenés:European Journal of Neurology. - 14 : Suppl. 1 (2007), p. 1-. -
További szerzők:Orbán-Kis Károly Szász J. A. Bajkó Z. Fekete Klára (1978-) (neurológus) Szatmári Szabolcs (1960-) (neurológus)
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6.

001-es BibID:BIBFORM091004
Első szerző:Tsivgoulis, Georgios
Cím:Intravenous thrombolysis for ischemic stroke in the golden hour : propensity-matched analysis from the SITS-EAST registry / Georgios Tsivgoulis, Aristeidis H. Katsanos, Pavla Kadlecova, Anna Czlonkowska, Adam Kobayashi, Miroslav Brozman, Viktor Švigelj, Laszlo Csiba, Klara Fekete, Janika Körv, Vida Demarin, Aleksandras Vilionskis, Dalius Jatuzis, Yakup Krespi, Chrissoula Liantinioti, Sotirios Giannopoulos, Robert Mikulik
Dátum:2017
ISSN:0340-5354
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journal Of Neurology. - 264 : 5 (2017), p. 912-920. -
További szerzők:Katsanos, Aristeidis H. Kadlecova, Pavla Czlonkowska, Anna Kobayashi, Adam Brozman, Miroslav Švigelj, Victor Csiba László (1952-) (neurológus, pszichiáter) Fekete Klára (1978-) (neurológus) Körv, Janika Demarin, Vida Vilionskis, Aleksandras Jatuzis, Dalius Krespi, Yakup Liantinioti, Chrissoula Giannopoulos, Sotirios Mikulík, Robert
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7.

001-es BibID:BIBFORM071091
035-os BibID:(WoS)000415723800016 (Scopus)85034075239
Első szerző:Tsivgoulis, Georgios
Cím:Intravenous thrombolysis for patients with in-hospital stroke onset : propensity-matched analysis from the Safe Implementation of Treatments in Stroke-East registry / Georgios Tsivgoulis, Aristeidis H. Katsanos, Pavla Kadlecová, Anna Czlonkowska, Adam Kobayashi, Miroslav Brozman, Viktor Švigelj, Laszlo Csiba, Klara Fekete, Janika Kõrv, Vida Demarin, Aleksandras Vilionskis, Dalius Jatuzis, Yakup Krespi, Theodore Karapanayiotides, Sotirios Giannopoulos, Robert Mikulik
Dátum:2017
ISSN:1351-5101
Megjegyzések:Introduction: Recent cross-sectional study data suggest that intravenous thrombolysis (IVT) in patients with in-hospital (IHS) acute ischemic stroke (AIS) onset is associated with unfavourable functional outcomes at hospital discharge and in-hospital mortality compared to patients with outof-hospital stroke onset (OHS) treated with IVT. We sought to compare outcomes between IVT treated IHS and OHS patients by analysing propensity score matched (PSM) data from the SITSEAST registry. Methods: We compared the following outcomes for all PSM patients: 1.symptomatic intracranial hemorrhage (sICH) defined with the SITS-MOST criteria, 2.favourable functional outcome Accepted ArticleThis article is protected by copyright. All rights reserved. (FFO) defined as a modified Rankin Scale (mRS) score of 0-1 at three months, 3.Functional independence (FI) defined as a mRS score of 0-2 at three months, 4.3-month mortality. Results: Out of total 19,077 IVT-treated AIS patients, 196 IHS patients were matched to 5124 OHS patients, with no differences in all baseline characteristics (p>0.1). IHS had longer door-to-needle [90 min (60-140) vs. 65 (47-95), p<0.001] and door-to-imaging times [40 min (20-90) vs 24 (15-35), p<0.001] compared to OHS. No differences were detected in the rates of sICH (1.6% vs 1.9%, p=0.756), FFO (46.4% vs 42.3%, p=0.257), FI (60.7% vs. 60.0%,p=0.447) and mortality (14.3% vs 15.1%,p=0.764). The distribution of 3-month mRS-scores was similar in the two groups (p=0.273). Conclusions: Our findings underline the safety and efficacy of IVT for IHS. They also underscore the potential of reducing in-hospital delays for timely tPA delivery in patients with IHS.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
intravenous thrombolysis
acute ischemic stroke
in-hospital stroke
onset-to-treatment time
door-to-needle time
stroke awareness
Megjelenés:European Journal of Neurology. - 24 : 12 (2017), p. 1493-1498. -
További szerzők:Katsanos, Aristeidis H. Kadlecova, Pavla Czlonkowska, Anna Kobayashi, Adam Brozman, Miroslav Švigelj, Victor Csiba László (1952-) (neurológus, pszichiáter) Fekete Klára (1978-) (neurológus) Kõrv, Janika Demarin, Vida Vilionskis, Aleksandras Jatuzis, Dalius Krespi, Yakup Karapanayiotides, Theodore Giannopoulos, Sotirios Mikulík, Robert
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