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001-es BibID:	BIBFORM069439
Első szerző:	Fekete Klára (neurológus)
Cím:	Outcome of Repeated Thrombolysis in Debrecen Thrombolysis Database / Klára Fekete, Sándor Márton, László Csiba, István Fekete
Dátum:	2017
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Journal of Stroke and Cerebrovascular Diseases. - 26 : 1 (2017), p. 132-138. -
További szerzők:	Márton Sándor (szociológus) Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM062617
Első szerző:	Fekete Klára (neurológus)
Cím:	Predictors of Long-term Outcome after Intravenous or Intra-arterial Recombinant Tissue Plasminogen Activator Treatment in the Eastern Hungarian Thrombolysis Database / Klára Fekete, Sándor Márton, Judit Tóth, László Csiba, István Fekete, Dániel Bereczki
Dátum:	2015
ISSN:	1052-3057 1532-8511
Megjegyzések:	Background: This prospective single-center study aimed to identify features determininglong-term outcome after thrombolysis in a Central European stroke population.Methods: Between 1 January, 2004, and 31 December, 2010, 415 patients weretreated with recombinant tissue plasminogen activator at the Department ofNeurology, University of Debrecen. Stroke severity by the National Institute ofHealth Stroke Scale score (NIHSSS) and imaging findings by the Alberta Stroke ProgrammeEarly Computed Tomography score (ASPECTS) were evaluated on admissionand 1 day later. The modified Rankin Scale (mRS) at 3 months and case fatalityat 1 year were evaluated. Independent predictors of outcome were identified bymultivariate testing. Results: Data of 369 patients were analyzed. Median NIHSSSwas 12 (interquartile range [IQR], 8-17) on admission and 10 (IQR, 5-16) at 24 hours.Arterial occlusion was found in 55%. Symptomatic intracerebral hemorrhage (SICH)was detected in 3.8%. Outcome was significantly worse, and SICH was morefrequent in intra-arterially treated patients. At 3 months, one third of the patientswere independent (mRS #2), and 23% were dead. At 1 year 2 of 3 patients were alive.Significant independent predictors of disability at 3 months were 24-hour NIHSSS,admission ASPECTS, admission glucose level, and treatment modality. Only the24-hour NIHSSS was a significant predictor of case fatality at 1 year. Conclusions:Although short-term outcome was similar, the 3-month and 1-year outcomes wereworse than data from previous reports. A more efficient health care program shouldbe implemented after stroke to maintain the favorable effect of thrombolysis in thelong term.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Ischemic stroke thrombolysis predictors outcome
Megjelenés:	Journal Of Stroke And Cerebrovascular Diseases. - 24 : 1 (2015), p. 117-124. -
További szerzők:	Márton Sándor (szociológus) Tóth Judit Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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001-es BibID:	BIBFORM049525
Első szerző:	Fekete Klára (neurológus)
Cím:	Prestroke Alcohol Consumption and Smoking Are Not Associated with Stroke Severity, Disability at Discharge, and Case Fatality / Klára Fekete, Szabolcs Szatmári, Ildikó Szőcs, Csilla Szekeres, József Szász, László Mihálka, Volodymyr Smolanka, László Kardos, László Csiba, Dániel Bereczki
Dátum:	2014
Megjegyzések:	Background: Heavy alcohol consumption and smoking are known risk factors for stroke but their influence on stroke severity and outcome may also be important. We tested if alcohol consumption and smoking relate to initial stroke severity, disability at discharge from hospital and outcome at 30 days and at 1 year in 1049 patients of the Mures-Uzhgorod-Debrecen database. Methods: Initial stroke severity was scored by the NIH stroke scale. Case fatality and the modified outcome scale of the 1st International Stroke Trial were used to assess outcome. We used multiple regression analysis.Results: Before their stroke, 24.5% were smokers and 24.7 % admitted regular alcohol consumption. Neither smoking nor alcohol consumption status were associated with initial stroke severity. Case fatality at discharge, at 30 days and at 1 year were 12.2%, 16.9% and 28.3%, respectively. Initial stroke severity, hemorrhagic subtype, and age in men over 60 years were strong predictors of outcome. We did not find significant difference among alcohol consumers and non-consumers in 30-day and in one year case fatality in all stroke patients and in ischemic stroke patients. In hemorrhagic stroke, there was a non-significant tendency for higher case fatality among alcohol-consumers (39.5% vs. 26.4%, p>0.2 at 30 days and 48.8% vs. 35.8%, p>0.2 at 1 year). Smoking did not influence significantly the outcome at 30-days and at one-year.Conclusion: despite being risk factors, pre-stroke smoking and alcohol consumption do not have a significant influence on stroke severity and on short- and long- term outcome.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Alcohol, smoking and stroke severity
Megjelenés:	Journal of Stroke and Cerebrovascular Diseases. - 23 : 1 (2014), p. e31-e37. -
További szerzők:	Szatmári Szabolcs (1960-) (neurológus) Szőcs Ildikó (1970-) (orvos) Szekeres Csilla Cecília (1980-) (orvos) Szász József (1960-) (neurológus) Mihálka László (1950-) (neurológus) Smolanka, Volodymyr I. (1950-) (orvos) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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