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1.

001-es BibID:BIBFORM079172
035-os BibID:(WoS)000500179300045 (Scopus)85065468894
Első szerző:Balogh Enikő
Cím:Effectiveness of the Gerundium Youth Educating Program in Hungary / E. Balogh, B. Szabó, A. K. Varga, B. Tóth, D. Kovács, L. Asztalos, B. Nemes
Dátum:2019
ISSN:0041-1345
Megjegyzések: The acceptance of brain death and the legitimation of organ transplantation is very much dependent on the general knowledge of the society. In Hungary, the legislation of brain death is based on presumed consent. There is no structural education about the topic so far. Aim The role of the Gerundium program is to educate high school students about the importance of transplantation and the meaning of brain death. The goal of this study was to evaluate the effectiveness of the Gerundium contemporary educational program in a pilot study. Method The education was held by medical students who successfully completed a preparatory elective course consisting of relevant information in the topic. Medical students used simple language during the 45-minute presentations. Two tests with simple but representative questions created by experts were completed by high school students: one directly before contemporary education and another 5 to 6 weeks after the lecture. Results A total of 147 tests were completed: 78 before and 69 after the presentation in the city of Debrecen and 294 before the lecture in the city of Győr. In Debrecen, the overall correct answers increased by 6.05% ( P < .05; before vs after). The results show that the knowledge transfer is highly effective in this manner and the students know significantly more weeks after the lectures. Conclusion There is much to do to broadly inform society about transplantation and brain death, but we will continue to increase the number of students and measure the dynamic change of the students' knowledge.
Tárgyszavak:Orvostudományok Klinikai orvostudományok konferenciacikk
folyóiratcikk
gerundium
Megjelenés:Transplantation Proceedings. - 51 : 4 (2019), p. 1209-1214. -
További szerzők:Szabó Balázs (1991-) (általános orvos) Varga A. K. Tóth B. Kovács Dávid Ágoston (1982-) (sebész) Asztalos László (1951-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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2.

001-es BibID:BIBFORM105891
035-os BibID:(WOS)000911722700001 (Scopus)85141973908
Első szerző:Illésy Lóránt (sebész)
Cím:Ureteral Complications Requiring Intervention After Kidney Transplant : A Single-Center Experience / Illésy Lóránt, Kovács Dávid Ágoston, Fedor Roland, Zádori Gergely, Kanyári Zsolt, Asztalos László, Nemes Balázs
Dátum:2022
ISSN:0041-1345
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Transplantation Proceedings. - 54 : 9 (2022), p. 2578-2583. -
További szerzők:Kovács Dávid Ágoston (1982-) (sebész) Fedor Roland (1975-) (sebész) Zádori Gergely (1983-) (sebész) Kanyári Zsolt (1964-) (orvos) Asztalos László (1951-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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3.

001-es BibID:BIBFORM078819
035-os BibID:(WoS)000500179300060 (Scopus)85065483146
Első szerző:Illésy Lóránt (sebész)
Cím:Non-Hodgkin Lymphoma in a Kidney Transplant Patient : a Case Report / Lóránt Illésy, Réka P. Szabó, Dávid Ágoston Kovács, Roland Fedor, Balázs Nemes
Dátum:2019
ISSN:0041-1345
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Transplantation Proceedings. - 51 : 4 (2019), p. 1286-1288. -
További szerzők:P. Szabó Réka (1979-) (orvos) Kovács Dávid Ágoston (1982-) (sebész) Fedor Roland (1975-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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4.

001-es BibID:BIBFORM073248
035-os BibID:(WoS)000408790300003 (Scopus)85027996499
Első szerző:Illésy Lóránt (sebész)
Cím:Autosomal Dominant Polycystic Kidney Disease Transplant Recipients After Kidney Transplantation : a Single-center Experience / L. Illesy, D. Á. Kovács, R. P. Szabó, A. B. L. Asztalos, B. Nemes
Dátum:2017
ISSN:0041-1345
Megjegyzések:Kidney transplantation is indicated for end-stage renal disease. Autosomal dominant polycystic kidney disease (ADPKD) causes structural degeneration of the kidney and eventually becomes end-stage renal disease. ADPKD patients usually have several renal and nonrenal complications. We analyzed our kidney transplantation activities between 1991 and 2010 regarding ADPKD. We followed up with patients to December 31, 2016. Data were collected as patient and graft survival rates, the prevalence of polycystic manifestation of the gastrointestinal tract and other organs, and the attendance of urinary tract infection. Among the 734 kidney transplantations, 10.9% (n = 80) had an ADPKD. Four patients (5%) had diverticulum perforation. The prevalence of post-transplantation urinary tract infection was higher in ADPKD patients (55.9%) compared to non-ADPKD patients (44.1%). The 1-, 3-, and 5-year overall survival rates in ADPKD recipients versus non-ADPKD patients are 77.5%, 70.0%, and 67.5% versus 86.4%, 83.0%, and 80.1%, respectively. Patients with ADPKD were transplanted at an elder age compared to others (median: 47.5 years vs. 39.9 years). Female patients had longer graft survival times than males. ADPKD implies multiple cystic degeneration of the kidneys; however, it can cause structural degeneration in other organs. It is typical for ADPKD patients to have an acute abdominal-like syndrome. Immunosuppressive drugs can hide the clinical picture, which makes early diagnosis difficult.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Transplantation Proceedings. - 49 : 7 (2017), p. 1522-1525. -
További szerzők:Kovács Dávid Ágoston (1982-) (sebész) P. Szabó Réka (1979-) (orvos) Asztalos László (1951-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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5.

001-es BibID:BIBFORM079170
035-os BibID:(WoS)000500179300051 (Scopus)85065488320
Első szerző:Kovács Dávid Ágoston (sebész)
Cím:Surgical Treatment of Hyperparathyroidism After Kidney Transplant / D. Á. Kovács, R. Fedor, L. Asztalos, M. Andrási, R. P. Szabó, Zs. Kanyári, S. Barna, B. Nemes, F. Győry
Dátum:2019
ISSN:0041-1345
Megjegyzések: Chronic renal impairment is often associated with complex bone disorders. Improvement of secondary hyperparathyroidism (HPT) is expected after kidney transplant (KT) if the glomerular filtration rate is normalized. Patients and Methods There were 888 KTs performed between 1996 and 2017 at our department. A total of 558 general patients have been operated on for HPT during the same period. The 2 populations had a common part: out of the 558, a total of 69 (12.4%) were in end-stage renal failure when operated on because of secondary HPT. That also means that 7.8% of all KTs were associated with HPT. Retrospective, single-center analysis was performed using the patients' medical records. The aim of our study was to analyze the results of parathyroidectomies after KT. Results Parathyroid surgery was performed on 19 patients (2.14%) because of HPT after KT. The applied surgical technique was total parathyroidectomy with autotransplant in 6 cases, subtotal parathyroidectomy in 3 cases, and selective parathyroidectomy in 10 cases. In all cases, histology revealed benign disease. Complications were observed in 10 cases (52%); there were 6 cases of postoperative hypocalcaemia (31.58%), 1 case of transient laryngeal recurrent nerve paresis (5.26%), and 6 cases of recurrent HPT (31.58%). Summary The first step of HPT management is calcimimetic drug treatment. It is essential to prevent possible complications with regular laboratory monitoring. If the proper conservative therapy is refractory or severe in complications, surgery should be chosen. If the patient is already waiting for a KT, it is worth performing the parathyroid surgery before KT. Close collaboration with endocrinologists and nephrologists is needed to achieve successful therapy.
Tárgyszavak:Orvostudományok Klinikai orvostudományok konferenciacikk
folyóiratcikk
hyperparathyroidisim
kidney transplant
Megjelenés:Transplantation Proceedings. - 51 : 4 (2019), p. 1244-1247. -
További szerzők:Fedor Roland (1975-) (sebész) Asztalos László (1951-) (sebész) Andrási M. P. Szabó Réka (1979-) (orvos) Kanyári Zsolt (1964-) (orvos) Barna Sándor (1982-) (kutató orvos) Nemes Balázs Áron (1969-) (sebész) Győry Ferenc (1964-) (sebész)
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6.

001-es BibID:BIBFORM067491
Első szerző:Kovács Dávid Ágoston (sebész)
Cím:Gerundium : a Comprehensive Public Educational Program on Organ Donation and Transplantation and Civil Law in Hungary / D. Á. Kovács, S. Mihály, K. Rajczy, L. Zsom, G. Zádori, R. Fedor, E. Kaáli, E. Balogh, L. Asztalos, B. Nemes
Dátum:2015
ISSN:0041-1345
Megjegyzések:bstractBACKGROUND:Organ transplantation has become an organized, routine, widely used method in the treatment of several end-stage diseases. Kidney transplantation means the best life-quality and longest life expectancy for patients with end-stage renal diseases. Transplantation is the only available long-term medical treatment for patients with end-stage liver, heart, and lung diseases. Despite the number of transplantations increasing worldwide, the needs of the waiting lists remain below expectations.METHODS:One of the few methods to increase the number of transplantations is public education. In cooperation with the University of Debrecen Institute for Surgery Department of Transplantation, the Hungarian National Blood Transfusion Service Organ Coordination Office, and the Local Committee Debrecen of Hungarian Medical Students' International Relations Committee (HuMSIRC), the Gerundium, a new educational program, has been established to serve this target. Gerundium is a special program designed especially for youth education. Peer education means that age-related medical student volunteers educate their peers during interactive unofficial sessions.RESULTS:Volunteers were trained during specially designed training. Medical students were honored by HuMSIRC, depending on their activity on the basis of their own regulations. Uniform slides and brochures to share were designed. Every Hungarian secondary school was informed. The Local Committee Budapest of HuMSIRC also joined the program, which helps to expand our activity throughout Hungary. The aim of the program is public education to help disperse disapproval, if presented.CONCLUSIONS:As a multiple effect, our program promotes medical students to have better skills in the field of transplantation, presentation, and communication skills. Our program is a voluntary program with strong professional support and is free of charge for the community.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
organ
donation
transplantation
civil
law
hungary
Megjelenés:Transplantation Proceedings 47 : 7 (2015), p. 2186-2188. -
További szerzők:Mihály Sándor Rajczy Katalin Zsom Lajos (1968-) (belgyógyász, nefrológus) Zádori Gergely (1983-) (sebész) Fedor Roland (1975-) (sebész) Kaáli Eszter Balogh Enikő Asztalos László (1951-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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7.

001-es BibID:BIBFORM054356
Első szerző:Kovács Dávid Ágoston (sebész)
Cím:Three-year longitudinal clinical trial of arterial function assessed by a oscillometric non-invasive method in comparison with carotid sclerosis and transferrin kidney-transplanted patients / D. Kovács, L. Lőcsey, R. Laczik, L. Szabó, L. Zsom, K. Kabai, R. Fedor, B. Nemes, L. Asztalos, P. Soltész
Dátum:2014
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Transplantation Proceedings 46 : 6 (2014), p. 2168-2170. -
További szerzők:Lőcsey Lajos (1946-2013) (belgyógyász, nephrológus) Laczik Renáta (1982-) (orvos) Szabó László (1975-) (sebész) Zsom Lajos (1968-) (belgyógyász, nefrológus) Kabai Krisztina Fedor Roland (1975-) (sebész) Nemes Balázs Áron (1969-) (sebész) Asztalos László (1951-) (sebész) Soltész Pál (1961-) (belgyógyász, kardiológus)
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8.

001-es BibID:BIBFORM051725
035-os BibID:PMID:24314996 WOS:000328304700069
Első szerző:Kovács Dávid Ágoston (sebész)
Cím:Noninvasive perioperative monitoring of arterial function in patients with kidney transplantation / D. Kovács, L. Löcsey, L. Szabó, R. Fedor, R. Laczik, L. Asztalos, P. Soltész
Dátum:2013
Megjegyzések:Development of atherosclerosis is accelerated in kidney transplant recipients. Impaired metabolic pathways have a complex effect on the arterial wall, which can be measured by noninvasive techniques. Few data are available on the change of stiffness parameters in the postoperative course, so in this study we analyzed the stiffness parameters of kidney transplant recipients during the perioperative period. Seventeen successful primary kidney transplant patients with uneventful postoperative period (7 woman, 10 men; 46.16 ± 12.19 years) were involved in our short-term prospective longitudinal study. We analyzed the correlation between noninvasively assessed stiffness parameters (pulse wave velocity [PWV], augmentation index [AIx], pulse pressure [PP], systolic area index, diastolic area index, diastolic reflection area), ankle-brachial index (ABI), and laboratory parameters (creatinine, glomerular filtration rate, urea, haemoglobin, C-reactive protein). Stiffness parameters were measured with a Tensiomed Arteriograph. These parameters were assessed before the transplantation, and 24 hours, and 1 and 2 weeks after surgery under standard conditions. We found that creatinine (P = .0008) and C-reactive protein (P = .006) serum levels decreased, and glomerular filtration rate increased significantly (P = .0005). We revealed that PWV (P = .0075) and AIx (P = .013) improved significantly. There was no significant change in ABI, PP, and the other monitored parameters. Along with the available data in the literature, our findings suggest that kidney transplantation has a positive effect on the arterial function.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Transplantation Proceedings 45 : 10 (2013), p. 3682-3684. -
További szerzők:Lőcsey Lajos (1946-2013) (belgyógyász, nephrológus) Szabó László (1975-) (sebész) Fedor Roland (1975-) (sebész) Laczik Renáta (1982-) (orvos) Asztalos László (1951-) (sebész) Soltész Pál (1961-) (belgyógyász, kardiológus)
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9.

001-es BibID:BIBFORM019304
Első szerző:Kovács Dávid Ágoston (sebész)
Cím:Prospective Study of Changes in Arterial Stiffness among Kidney-Transplanted Patients / Kovács, D., Szabó, L., Fedor, R., Laczik, R., Soltész, P., Lőcsey, L., Asztalos, L.
Dátum:2011
ISSN:0041-1345
Megjegyzések:Chronic kidney disease is one of the main risk factors for cardiovascular disease. Changes in stiffness parameters can predict the higher risk of the development of cardiovascular disease. METHODS: Cadaveric donor kidney transplant patients (n=184) were followed in a cross-sectional single-center study. Arterial stiffness parameters were measured by arteriography. We analyzed the correlation between stiffness parameters and immunosuppressive therapy, the main operation parameters, patient age, elapsed time since transplantation, carotid artery stenosis, and septual wall thickness. We enrolled 24 patients in a 3-year longitudinal study to analyze changes in stiffness parameters. RESULTS: Our cross-sectional study showed pulse wave velocity (PWV) to be significantly related to the age of the patient (P=.0001; r=0.41). There was no significant correlation between the stiffness parameters and type or dosage of immunosuppressive drugs and number of transplantations. We noted significant correlations between pulse pressure (PP) and pulse wave velocity (PWV), and augmentation index (AI) (P=.01). Patients with abnormal PWV (>12 m/s) showed significantly higher systolic blood pressures, body mass indexes, PP, and AI (P<.01). Our 3-year longitudinal study revealed a significant elevation in PWV. CONCLUSIONS: Improving endothelial function and prevention of atherosclerosis may help to reduce cardiovascular complications. Among chronic kidney disease patients, early transplantation is a possible way to prevent cardiovascular events. It is better to perform the transplantation at as early an age as possible.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Transplantation Proceedings 43 : 4 (2011), p. 1252-1253. -
További szerzők:Szabó László (1975-) (sebész) Fedor Roland (1975-) (sebész) Laczik Renáta (1982-) (orvos) Soltész Pál (1961-) (belgyógyász, kardiológus) Lőcsey Lajos (1946-2013) (belgyógyász, nephrológus) Asztalos László (1951-) (sebész)
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10.

001-es BibID:BIBFORM049039
035-os BibID:PMID:24314997 WOS:000328304700070
Első szerző:Lőcsey Lajos (belgyógyász, nephrológus)
Cím:Relationship Between Serum Paraoxonase and Homocysteine Thiolactonase Activity, Adipokines, and Asymmetric Dimethyl Arginine Concentrations in Renal Transplant Patients / L. Locsey, I. Seres, F. Sztanek, M. Harangi, J. Padra, D. Kovacs, R. Fedor, L. Asztalos, G. Paragh
Dátum:2013
ISSN:0041-1345
Megjegyzések:Paraoxonase lactonase activity protects against homocysteinylation; therefore, it can be a potential contributing factor to prevent atherosclerosis. We aimed to determine paraoxonase and HTLase activities and to clarify the relationship between HTLase activity and some cardiovascular risk factors, such as homocysteine, cystatin C asymmetric dimethylarginine (ADMA), and adipokines both in hemo dialyzed and transplanted patients. Among 114 hemodialyzed, 80 transplanted and 64 healthy control subjects, we investigated body mass index (BMI) as well as fasting serum contents of urea, uric acid, creatinine, cystatin C, homocysteine, glucose, lipids, total protein and albumin. Serum paraoxonase (PON 1) and HTLase activities were measured spectrophotometrically. ADMA, ADPN adiponectin, leptin (LEP) levels was determined with a sandwich enzyme-linked immunosorbent assay method. Dyslipidemic patients showed hypercholesterolemia, and high low-density lipoprotein (LDL); parallel with improved renal function, they displayed decreased cystatin C and homocysteine levels (P < .001). There was a significant negative correlation between PON 1 activity and cystatin C and homocysteine concentrations (P < .05). Obese patients revealed significantly higher LDL (P < .05) and leptin concentrations (P < .01). There was a significant positive correlation between PON 1 activity and adiponectin levels (P = .0276). Both dialyzed and transplanted patients displayed significantly lower HTLase activities compared to the control group (P < .001), particularly lower HTLase and PON 1 activities in dialyzed subjects compared with the transplanted group (P < .05). HTLase activity showed significant negative correlations with ADMA levels among the whole study population (P < .001), whereas positive associations were noted between PON 1 and HTLase activities (P < .001). HTLase activity may be a new predictor of cardiovascular risk in renal failure although it is modulated by other risk factors.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Transplantation Proceedings. - 45 : 10 (2013), p. 3685-3687. -
További szerzők:Seres Ildikó (1954-) (biokémikus) Sztanek Ferenc (1982-) (orvos) Harangi Mariann (1974-) (belgyógyász, endokrinológus) Padra János Tamás (1984-) (biológus) Kovács Dávid Ágoston (1982-) (sebész) Fedor Roland (1975-) (sebész) Asztalos László (1951-) (sebész) Paragh György (1953-) (belgyógyász)
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11.

001-es BibID:BIBFORM067492
035-os BibID:(WoS)000386317900075 (Scopus)84992323992
Első szerző:Szabó-Pap Marcell
Cím:Surgical Complications Following Kidney Transplantations : a Single-Center Study in Hungary / M. Szabo-Pap, G. Zadori, R. Fedor, L. Illesy, F. Toth, Z. Kanyari, D. A. Kovacs, B. Nemes
Dátum:2016
ISSN:0041-1345
Megjegyzések:ABSTRACTSurgical complications (SCs) are still high potential causes of graft loss. The incidence has ahuge amount of variations depending on many factors. Our aim was to study the postoperativetechnical complications following kidney transplantations (KTs) during a 5-yearperiod between 2011 and 2015. In the observed time frame there were 47 SCs occurring in32 (19.4%) patients of 165 KTs. Every complication was classified into 3 groups: vascular(11; 6.6%), urologic (16; 9.7%), and any others (20; 12.1%). The most common postoperativeSCs in our center were hemorrhage (14; 8.5%), urinary leakage (12; 7.2%), andrenal artery stenosis (6; 3.6%). Twenty-seven patients, 84% of those having had a SC,needed an intervention, mainly a surgical correction (28; 62%). Half of these interventions(21; 51%) were performed due to urologic reasons. As possible predicting factors, westudied the type of arterial and ureter anastomosis in relation to onset of vascular andurologic complications. There was no significant correlation. The same was true for anydonor and/or recipient demographic parameters. However, the presence of SCs impairedboth patient and graft survival. The cumulative 6-month, 1-, 3-, and 5-year patient survivalrates were 97% versus 99%, 93% versus 99%, 84% versus 97%, and 84% versus 97% forpatients with/without (w/wo) a SC, respectively (P ? .028). The cumulative 6-month, 1-, 3-,and 5-year graft survival rates were 81% versus 96%, 77% versus 94%, 68% versus 86%,and 54% versus 86% for the same 2 groups, respectively (P ? .003).
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
kidney
transplantation
study
Hungary
complications
Megjelenés:Transplantation Proceedings. - 48 : 7 (2016), p. 2548-2551. -
További szerzők:Zádori Gergely (1983-) (sebész) Fedor Roland (1975-) (sebész) Illésy Lóránt (1991-) (sebész) Tóth Fruzsina Kanyári Zsolt (1964-) (orvos) Kovács Dávid Ágoston (1982-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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12.

001-es BibID:BIBFORM067527
035-os BibID:(WoS)000386317900076 (Scopus)84992402727
Első szerző:Tóth Fruzsina
Cím:A Single-center Experience of Allograft Nephrectomies Following Kidney Transplantation / F. Toth, G. Zadori, R. Fedor, L. Illesy, M. Szabo-Pap, Z. Kanyari, D. A. Kovacs, L. Asztalos, B. Nemes
Dátum:2016
ISSN:0041-1345
Megjegyzések:AbstractIntroductionApproximately 10% of renal allografts fail during the first year after kidney transplantation (KT) and 3%?5% thereafter yearly. The indication and timing of allograft nephrectomy (AN) is still uncertain in some cases. The aim of this study was to reveal the ratio, etiology, and complications of AN at our center.Material and MethodsThis is a retrospective study of all patients who underwent KT at our center between January 1, 2004 and December 31, 2014. We analysed the frequency, indications, timing, and complications of ANs. Also early and late ANs were compared.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
experience
allograft
nephrectomie
kidney
transplant
Megjelenés:Transplantation Proceedings. - 48 : 7 (2016), p. 2552-2554. -
További szerzők:Zádori Gergely (1983-) (sebész) Fedor Roland (1975-) (sebész) Illésy Lóránt (1991-) (sebész) Szabó-Pap Marcell Kanyári Zsolt (1964-) (orvos) Kovács Dávid Ágoston (1982-) (sebész) Asztalos László (1951-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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