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001-es BibID:	BIBFORM062133
Első szerző:	Péter Andrea (kardiológus)
Cím:	Echocardiographic abnormalities in new-onset polymyositis/dermatomyositis / Andrea Péter, Ágnes Balogh, Szabolcs Szilágyi, Réka Faludi, Melinda Nagy-Vincze, István Édes, Katalin Dankó
Dátum:	2015
Megjegyzések:	OBJECTIVE:To identify early echocardiographic abnormalities at the time of diagnosis of polymyositis (PM) and dermatomyositis (DM) and follow the echocardiographic findings during the first 3 months of therapy.METHODS:We included 30 PM/DM patients (23/7) with a mean age of 42.3 ? 1.6 years and without cardiovascular symptoms. Age-matched healthy patients served as controls. Clinical characteristics were recorded. Traditional echocardiography and tissue Doppler imaging (TDI) were performed to measure systolic [ejection fraction, right ventricular fractional area change (RV FAC), lateral and tricuspid annulus s velocities] and diastolic echocardiographic variables (mitral inflow velocities: E, A; deceleration time: DT; lateral and tricuspid annulus e', a' velocities, lateral E/e').RESULTS:The left and right ventricular systolic dysfunction detected by TDI at the time of the PM/DM diagnosis improved, and characteristic values at the end of the followup period were comparable to those of the controls (lateral s: 10.6 ? 0.2, 8.7 ? 0.4, 9.6 ? 0.3, 11.3 ? 0.2 cm/s; RV FAC: 45.2 ? 2.3, 36.9 ? 1.5, 42.2 ? 1.3, 46.9 ? 1.2%; tricuspid s: 13.3 ? 0.2, 9.5 ? 0.4, 10.3 ? 0.3, 11.6 ? 0.5 cm/s; control, 0, 1, and 3 mos, respectively). Measurements indicated the development of diastolic dysfunction at 3 mos (E/A: 1.4 ? 0.1, 1.29 ? 0.05, 1.03 ? 0.05, 0.92 ? 0.05; DT: 148.6 ? 3.6, 157.3 ? 5.7, 168.3 ? 6.0, 184.3 ? 6.2 ms; lateral e': 12.8 ? 0.3, 12.1 ? 0.5, 10.2 ? 0.6, 10.8 ? 0.8 cm/s; E/e': 5.6 ? 0.1, 5.0 ? 0.22, 6.92 ? 0.46, 7.64 ? 0.47; control, 0, 1, and 3 mos, respectively).CONCLUSION:TDI is a useful method to detect early cardiac abnormalities complementing the conventional echocardiographic measurements. LV and RV systolic dysfunction found in the acute phase significantly improved during the first 3 months of therapy; however, deterioration of diastolic dysfunction was also observed.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk DERMATOMYOSITIS ECHOCARDIOGRAPHY POLYMYOSITIS SYSTOLIC AND DIASTOLIC DYSFUNCTION TISSUE DOPPLER IMAGING
Megjelenés:	The Journal of rheumatology. - 42 : 2 (2015), p. 272-281. -
További szerzők:	Balogh Ágnes (1984-) (kardiológus) Szilágyi Szabolcs (1976-) (kardiológus) Faludi Réka Nagy-Vincze Melinda (1985-) (orvos) Édes István (1952-) (kardiológus) Dankó Katalin (1952-2021) (belgyógyász, allergológus és klinikai immunológus)
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001-es BibID:	BIBFORM033001
035-os BibID:	PMID:22134617
Első szerző:	Szilágyi Szabolcs (kardiológus)
Cím:	Recurrent arterial thrombosis associated with the antithrombin basel variant and elevated lipoprotein(a) plasma level in an adolescent patient / Szabolcs Szilagyi, Andrea Peter, Maria Tünde Magyar, Sandor Balogh, Zsuzsanna Bereczky
Dátum:	2012
Megjegyzések:	Both myocardial infarction and ischemic stroke are rare in the young. Yet a 15-year-old male patient suffered a myocardial infarction and later an ischemic stroke despite uninterrupted antiplatelet therapy. His medical history involved the surgical correction of an incomplete atrioventricular canal defect at the age of 13 years. No cardiovascular risk factors other than elevated lipoprotein(a) level could be identified. His antithrombin (AT) activity was decreased and DNA sequence analysis revealed heterozygosity for AT Basel (p.Pro41Leu), a variant with impaired heparin binding. This report supports a possible additional pathophysiological role for AT Basel and elevated lipoprotein(a) level in arterial thrombogenesis.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Journal of Pediatric Hematology/Oncology 34 : 4 (2012), p. 276-279. -
További szerzők:	Péter Andrea (1967) (kardiológus) Magyar Mária Tünde (1970-) (neurológus) Balogh Sándor Bereczky Zsuzsanna (1974-) (orvosi laboratóriumi diagnosztika szakorvos)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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