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001-es BibID:	BIBFORM102792
035-os BibID:	(cikkazonosító)e220078
Első szerző:	Erdei Annamária (belgyógyász)
Cím:	Non-surgical orbital decompression using diuresis in dysthyroid optic neuropathy : a case report / Erdei Annamaria, Gazdag Annamaria, Ujhelyi Bernadett, Nagy Edit B., Berenyi Ervin, Berta Eszter, Steiber Zita, Barna Sandor, Mezosi Emese, Bodor Miklos, V. Nagy Endre
Dátum:	2022
ISSN:	2235-0640 2235-0802
Megjegyzések:	Introduction: Dysthyroid optic neuropathy (DON) is a rare, severe form of thyroid eye disease, in which decreased visual acuity is accompanied by characteristic MRI findings. The treatment of DON has always been a challenge. Case presentation: In a patient in whom visual acuity deteriorated on the left eye, mannitol 20% 200 mL followed by furosemide 40 mg 6 h later, administered daily, were initiated on the day of admission. Visual function by ophthalmology methods, and orbital compartment volumes and water content by MRI were followed. Intravenous diuretics resulted in an immediate therapeutic response. Visual acuity improved from 20/50 to 20/25 after 2 days of treatment. MRI revealed decreasing water content of both the muscle and connective tissue compartments without any volume changes. Subsequently, corticosteroids and orbital irradiation were started. Orbital decompression surgery was not required. Discussion/conclusion: Edematous swelling of orbital tissues is an established contributor of local pressure increase in thyroid eye disease. Diuretics reduce orbital pressure and, if confirmed by others, may be useful additions to the standard of care in sight-threatening DON.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk MRI diuretics dysthyroid optic neuropathy thyroid eye disease
Megjelenés:	European Thyroid Journal. - 11 : 5 (2022), p. 1-10. -
További szerzők:	Gazdag Annamária (1979-) (belgyógyász) Ujhelyi Bernadett (1981-) (szemész) Nagy Edit B. Berényi Ervin (1964-) (radiológus) Berta Eszter (1980-) (belgyógyász) Steiber Zita (1977-) (orvos, szemész) Barna Sándor (1982-) (kutató orvos) Mezősi Emese Bodor Miklós (1969-) (belgyógyász, endokrinológus) Nagy Endre V. (1957-) (belgyógyász, endokrinológus)
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001-es BibID:	BIBFORM071707
Első szerző:	Szujó Szabina
Cím:	The impact of post-radioiodine therapy SPECT/CT on early risk stratification in differentiated thyroid cancer : a bi-institutional study / Szujo Szabina, Sira Livia, Bajnok Laszlo, Bodis Beata, Gyory Ferenc, Nemes Orsolya, Rucz Karoly, Kenyeres Peter, Valkusz Zsuzsanna, Sepp Krisztian, Schmidt Erzsebet, Szabo Zsuszanna, Szekeres Sarolta, Zambo Katalin, Barna Sandor, Nagy Endre V., Mezosi, Emese
Dátum:	2017
ISSN:	1949-2553
Megjegyzések:	Objective: SPECT/CT has numerous advantages over planar and traditional SPECT images. The aim of this study was to evaluate the role of post-radioiodine therapy SPECT/CT of patients with differentiated thyroid cancer (DTC) in early risk classification and in prediction of late prognosis.Patients and methods: 323 consecutive patients were investigated after their first radioiodine treatment (1100?3700 MBq). Both whole body scan and SPECT/CT images of the head, neck, chest and abdomen regions were taken 4?6 days after radioiodine therapy. Patients were re-evaluated 9?12 months later as well as at the end of follow up (median 37 months).Results: Post-radioiodine therapy SPECT/CT showed metastases in 22% of patients. Lymph node, lung and bone metastases were detected in 61, 13 and 5 patients, respectively, resulting in early reclassification of 115 cases (36%). Noevidence of disease was found in 251 cases at 9?12 months after radioiodine treatment and 269 patients at the end of follow-up. To predict residual disease at the end offollow-up, the sensitivities, specificities and diagnostic accuracies of the current risk classification systems and SPECT/CT were: ATA: 77%, 47% and 53%; ETA: 70%,62% and 64%; SPECT/CT: 61%, 88% and 83%, respectively. There was no difference between cohorts of the two institutions when data were analyzed separately.Conclusions: Based on our bi-institutional experience, the accuracy of postradioiodine SPECT/CT outweighs that of the currently used ATA and ETA risk classification systems in the prediction of long-term outcome of DTC.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban differentiated thyroid cancer radioiodine therapy SPECT/CT ATA risk classification ETA risk classification
Megjelenés:	Oncotarget. - 8 : 45 (2017), p. 79825-79834. -
További szerzők:	Sira Lívia (1973-) (endokrinológus) Bajnok László (1961-) (belgyógyász) Bódis Beáta Győry Ferenc (1969-) (kardiológus) Nemes Orsolya Rucz Károly Kenyeres Péter Valkusz Zsuzsanna Sepp Krisztián Schmidt Erzsébet Szabó Zsuszanna (Pécs) Szekeres Sarolta Zámbó Katalin Barna Sándor (1982-) (kutató orvos) Nagy Endre V. (1957-) (belgyógyász, endokrinológus) Mezősi Emese
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