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001-es BibID:	BIBFORM105948
035-os BibID:	(cikkazonosító)1610377 (scopus)85133546129 (wos)000817887200001
Első szerző:	Mátrai Zoltán
Cím:	Modern Breast Cancer Surgery 1st Central-Eastern European Professional Consensus Statement on Breast Cancer / Mátrai Zoltán, Kelemen Péter, Kósa Csaba, Maráz Róbert, Paszt Attila, Pavlovics Gábor, Sávolt Ákos, Simonka Zsolt, Tóth Dezső, Kásler Miklós, Kaprin Andrey, Krivorotko Petr, Vicko Ferenc, Pluta Piotr, Kolacinska-Wow Agnieszka, Murawa Dawid, Jankau Jerzy, Ciesla Slawomir, Dyttert Daniel, Sabol Martin, Zhygulin Andrii, Avetisyan Artur, Bessonov Alexander, Lázár György, Central-Eastern European Academy of Oncology (CEEAO) International Professional Panel
Dátum:	2022
ISSN:	1219-4956 1532-2807
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Pathology & Oncology Research. - 28 (2022), p. 57-75. -
További szerzők:	Kelemen Péter Kósa Csaba (1971-) (sebész) Maráz Róbert Paszt Attila Pavlovics Gábor Sávolt Ákos Simonka Zsolt Tóth Dezső (1972-) (sebész, onkológus) Kásler Miklós Kaprin, Andrey Krivorotko, Petr Vicko Ferenc Pluta, Piotr Kolacinska-Wow, Agnieszka Murawa, Dawid Jankau, Jerzy Ciesla, Slawomir Dyttert, Daniel Sabol, Martin Zhygulin, Andrii Avetisyan, Artur Bessonov, Alexander Lázár György Central-Eastern European Academy of Oncology (CEEAO) International Professional Panel
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001-es BibID:	BIBFORM073024
035-os BibID:	(WoS)000366646400029 (Scopus)84951907147
Első szerző:	Tóth Dezső (sebész, onkológus)
Cím:	Predictive Factors for Positive Margin and the Surgical Learning Curve in Non-Palpable Breast Cancer After Wire-Guided Localization - Prospective Study of 214 Consecutive Patients / Dezső Tóth, Zsolt Varga, Éva Sebő, Miklós Török, Ilona Kovács
Dátum:	2016
ISSN:	1219-4956 1532-2807
Megjegyzések:	To investigate the most commonly used technique, the wire-guided localization (WGL) in non-palpable breast cancer. To analyze the effective factors on positive surgical margins in our practice and determine the surgical learning curve of this method. Prospective consecutive study was performed from January 2005 to December 2011. Inclusion criteria was a non-palpable breast lesion with malignancy on preoperative histology. All lesions were localized by ultrasound or stereotactic guided wire placement. Margins 1 mm or closer were accepted as positive margins which required re-excision. To determine the learning curve of WGL method we investigated the change in the reoperation rate after primary procedure performed by "high-volume" surgeon. Two hundred and fourteen consecutive patients were enrolled. In 23 patients (10.7%) reexcision was needed. Positive surgical margins were significantly influenced by the patient's age (p?=?0.03), tumor volume (p?<?=0.001), proportion of tumor volume/specimen volume (p?<?0.001), presence of DCIS (p?<?0.001), multifocality (p?=?0.03) and the learning curve (p?=?0.006) with univariate analysis. Only the tumor volume, presence of DCIS and the learning curve were proved as independent prognostic factor for reoperation by multivariate analysis. The reoperation rate decreased below 20% after the fortieth operation. Results of our single institutional study suggest, that this localization technique can be performed safely with very good results after 40 procedures as a learning curve for surgeons.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Breast cancer Learning curve Non-palpable Surgery Wire-guided localization
Megjelenés:	Pathology & Oncology Research. - 22 : 1 (2016), p. 209-215. -
További szerzők:	Varga Zsolt József (1987-) (orvos) Sebő Éva Török Miklós (1976-) (pathológus) Kovács Ilona (1965-) (patológus)
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001-es BibID:	BIBFORM112933
035-os BibID:	(cikkazonosító)1611270 (WoS)001028006400001 (Scopus)85164849700
Első szerző:	Varga Zsolt József (orvos)
Cím:	A combined approach for individualized lymphadenectomy in gastric cancer patients / Zsolt Varga, Adrienn Biró, Miklós Török, Dezső Tóth
Dátum:	2023
ISSN:	1219-4956 1532-2807
Megjegyzések:	Introduction: Gastric cancer ranks as the fifth most common cancer globally. The presence of lymph node metastasis is a significant prognostic factor influencing survival. Postoperative morbidity and nodal staging accuracy are heavily affected by the extent of lymph node dissection. Our study aimed to explore the potential integration of two contemporary methods, sentinel node navigation surgery (SNNS) and the Maruyama Computer Program (MCP), to improve the accuracy of nodal staging. Materials and methods: We conducted a prospective data collection involving patients with gastric adenocarcinoma from 2008 to 2018 at the Department of Surgery, University of Debrecen, Hungary. Data from 100 consecutive patients were collected. The primary and secondary endpoints included evaluating the rate of node-negative patients and the diagnostic accuracy of our combined approach. Results: Sentinel node mapping was successful in 97 out of 100 patients. We found that using the threshold value of the Maruyama Index (MI) ? 28, all metastatic stations of sentinel-node-negative patients could be identified. Our method achieved 100% sensitivity and negative predictive value, with a specificity of 60.42% (95% CI = 46.31%?72.98%). Discussion: The combined application of SNNS and MCP has proven to be an effective diagnostic technique in the synergistic approach for identifying metastasis-positive lymph node stations. Despite its limitations, this combination may assist clinicians in customizing lymphadenectomy for gastric cancer patients.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk gyomorrák sebészet limfadenektómia sentinel Maruyama
Megjelenés:	Pathology & Oncology Research. - 29 (2023), p. 1-10. -
További szerzők:	Biró Adrienn (1988-) (orvos) Török Miklós (1976-) (pathológus) Tóth Dezső (1972-) (sebész, onkológus)
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