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1.

001-es BibID:BIBFORM112263
035-os BibID:(WoS)A1991GN29700004 (Scopus)0025998236
Első szerző:Arató Mihály
Cím:Serotonergic interhemispheric asymmetry: Neurochemical and pharmaco-EEG evidence / Arato Mihaly, Frecska Ede, MacCrimmon Duncan J., Guscott Rick, Saxena Bishan, Tekes Kornelia, Tothfalusi Laszlo
Dátum:1991
ISSN:0278-5846
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Progress In Neuro-Psychopharmacology & Biological Psychiatry. - 15 : 6 (1991), p. 759-764. -
További szerzők:Frecska Ede (1953-) (pszichiáter) MacCrimmon, Duncan J. Guscott, Rick Saxena, Bishan Tekes Kornélia Tóthfalusi László
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DOI
Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM034449
035-os BibID:PMID:14687873
Első szerző:Arató Mihály
Cím:Digit length pattern in schizophrenia suggests disturbed prenatal hemispheric lateralization / Mihaly Arató, Ede Frecska, Cindy Beck, Mary An, Huba Kiss
Dátum:2004
Megjegyzések:The differentiation of the human brain is triggered by sexual steroid hormones in the fetus. The development of both the urogenital system and the appendicular skeleton are under common control by the HOX genes. Generally men have longer ring fingers than index fingers, whereas in women these fingers are close to equal. The inborn digit pattern may reflect fetal estrogen/androgen influences on hemispheric brain specialization. Reduced hemispheric asymmetry has been found in schizophrenia. Gender differences in schizophrenia also suggest a possible endocrine component in the complex pathogenesis of the illness. To test this hypothesis the authors have measured the relative digit lengths of patients with schizophrenia and healthy comparison subjects. The distance of the tip of the index and ring finger was measured from the tip of the third digit in 80 male and 80 female, right-handed patients with DSM-IV diagnosis of schizophrenia and in 80 right-handed healthy comparison men and women. Schizophrenic men and women showed a more "feminine" phenotype of the index and ring fingers in both hands than same-sex controls. This finding implies that low fetal androgen/estrogen ratio may have a predisposing role in the development of schizophrenia and points toward involvement of endocrine factors in the disturbed hemispheric lateralization attributed to the illness.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
külföldön készült közlemény
Megjelenés:Progress in Neuro-Psychopharmacology and Biological Psychiatry. - 28 : 1 (2004), p. 191-194. -
További szerzők:Frecska Ede (1953-) (pszichiáter) Beck, Cindy An, Mary Kiss Huba
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM112284
035-os BibID:(WoS)A1985AGR5100010 (Scopus)0021966589
Első szerző:Bagdy György
Cím:Decrease in dopamine, its metabolites and noradrenaline in cerebrospinal fluid of schizophrenic patients after withdrawal of long-term neuroleptic treatment / G. Bagdy, A. Perényi, E. Frecska, K. Révai, Z. Papp, M. I. K. Fekete, M. Arató
Dátum:1985
ISSN:0033-3158
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Psychopharmacology. - 85 : 1 (1985), p. 62-64. -
További szerzők:Perényi András Frecska Ede (1953-) (pszichiáter) Révai Katalin Papp Z. Fekete I. K. Márton Arató Mihály
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Intézményi repozitóriumban (DEA) tárolt változat
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4.

001-es BibID:BIBFORM112266
035-os BibID:(WoS)A1991FH47400003 (Scopus)0025828261
Első szerző:Bartkó György
Cím:Effects of adjunctive verapamil administration in chronic schizophrenic patients / Bartko Gyorgy, Horvath Szabolcs, Zador Gyorgy, Frecska Ede
Dátum:1991
ISSN:0278-5846
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Progress In Neuro-Psychopharmacology & Biological Psychiatry. - 15 : 3 (1991), p. 343-349. -
További szerzők:Horváth Szabolcs Zádor György Frecska Ede (1953-) (pszichiáter)
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Intézményi repozitóriumban (DEA) tárolt változat
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5.

001-es BibID:BIBFORM034461
035-os BibID:PMID:9133752 WOS:A1997WU64600009
Első szerző:Edson, Robert
Cím:Interrater reliability issues in multicenter trials, part II : statistical procedures used in Department of Veterans Affairs Cooperative Study #3941 / Edson, R., Lavori, P., Tracy, K., Adler, L. A., Rotrosen, J., Gowda, S., Mukherjee, S., Williams, B., Duncan, E., Vaid, G., Schwartz, M., Hitzemann, R., Frecska, E., Manicone, P., Caroff, S., Campbell, E. C., Havey, J., Casey, D., Hoffman, W., Hansen, T., Brundage, T., Hixs, M., Hanna, M., Lohr, J., Browning, J., Kanof, P., Fain, R., Krystal, J., DSouza, D. C., Damon, D., Marder, S. S., Ames, D., Ross, D., Doorack, J., Hitzemann, R., Haakenson, C., Miller, M.
Dátum:1997
ISSN:0006-3223
Megjegyzések:The primary goal of Veterans Affairs (VA) Cooperative Study (CS) #394 is to determine if vitamin E is a safe and efficacious treatment for tardive dyskinesia (TD). The study uses various instruments to assess subjects for movement disorders (Abnormal Involuntary Movement Scale [AIMS], and Barnes Akathisia Scale [BAS]), psychopathology (Anchored Brief Psychiatric Rating Scale [BPRS]), and level of functioning (Global Assessment of Functioning scale [GAF]). Since the study involves nine sites, each with its own set of raters, it is important to establish and maintain high interrater reliability (IRR) on these instruments throughout the study and to identify raters who differ significantly from the others. To make this determination, personnel at each site assessed subjects from standardized videotapes on the AIMS, BAS, and Anchored BPRS, and rated written vignettes on the GAF. We fit these data to a two-way additive model to identify nonstandardized raters (i.e., those whose average ratings were significantly lower or higher than the others, or those whose scores, after adjusting for subject and rater effects, were highly variable). The proportion of nonstandardized raters ranged from 7 percent (Anchored BPRS) to 33 percent (AIMS). The estimated intraclass correlation coefficients (ICCs) indicated moderate reliability for the AIMS, BAS, and Anchored BPRS (0.73 to 0.75) and excellent agreement for the GAF (0.90). The companion article (Part I: Tracy et al. 1997, page 53 of this issue) describes the procedures used to train the raters for this study.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
külföldön készült közlemény
Megjelenés:Psychopharmacology Bulletin. - 33 : 1 (1997), p. 59-67. -
További szerzők:Lavori, Philip Tracy, Kathlene Adler, Lenard A. Rotrosen, John Gowda, S. Mukherjee, Subhendu Williams, B. Duncan, E. Vaid, G. Schwartz, M. Hitzemann, Robert Frecska Ede (1953-) (pszichiáter) Manicone, P. Caroff, Stanley Campbell, E. C. Havey, J. Casey, D. Hoffman, W. Hansen, T. Brundage, T. Hixs, M. Hanna, M. Lohr, J. Browning, J. Kanof, P. Fain, R. Krystal, J. DSouza, D. C. Damon, D. Marder, S. S. Ames, D. Ross, David Doorack, J. Hitzemann, R. Haakenson, C. Miller, M.
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6.

001-es BibID:BIBFORM034445
035-os BibID:PMID:14712339
Első szerző:Frecska Ede (pszichiáter)
Cím:Effects of ayahuasca on binocular rivalry with dichoptic stimulus alternation / E. Frecska, K. D. White, L. E. Luna
Dátum:2004
Megjegyzések:During binocular rivalry, two incompatible images are presented to each eye and these monocular stimuli compete for perceptual dominance, with one pattern temporarily suppressed from awareness. One variant of stimulus presentation in binocular rivalry experiments is dichoptic stimulus alternation (DSA), when stimuli are applied to the eyes in rapid reversals. There is preliminary report that in contrast with healthy controls, schizophrenic patients can maintain binocular rivalry even at very high DSA rates. The study was undertaken to investigate whether binocular rivalry survives high rates of DSA induced by the South American hallucinogenic beverage ayahuasca. Ten individuals who were participating in ayahuasca ceremonials were requested to volunteer for binocular rivalry tests (DSA=0, 3.75, 7.5, 15 and 30 Hz) without and after drinking the brew. Ingestion of ayahuasca increased mean dominance periods both in standard binocular rivalry conditions (no DSA) and tests with DSA. At higher DSA rates (15 and 30 Hz) the total length of dominance periods was longer on the brew. It is discussed that ayahuasca-induced survival of binocular rivalry at high DSA rates may be related to slow visual processing and increased mean dominance periods may result from hallucinogen-induced alteration of gamma oscillations in the visual pathways.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
külföldön készült közlemény
Megjelenés:Psychopharmacology. - 173 : 1-2 (2004), p. 79-87. -
További szerzők:White, Keith D. Luna, Luis Eduardo
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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7.

001-es BibID:BIBFORM034457
Első szerző:Frecska Ede (pszichiáter)
Cím:Opiate sensitivity test in patients with stereotypic movement disorder and trichotillomania / Ede Frecska; Mihaly Arato
Dátum:2002
Megjegyzések:Preliminary data about the therapeutic effect of opiate receptor manipulation in self-injurious behavior (SIB) suggest that endogenous opioid mechanisms may have a pathophysiological role in that condition and their involvement may be dependent on the severity of the SIB. The aim of this study was to use fentanyl-induced prolactin response as an opiate receptor sensitivity test in patients with stereotypic movement disorder (SMD) manifesting SIB (skin picking). Healthy volunteers and trichotillomanic patients were enrolled as comparison subjects. Individuals with trichotillomania (TTM) manifest repetitive, less serious self-mutilation (hair pulling) and are classified under different DSM-IV category than SMD. Therefore, they were considered as patient controls. Ten healthy subjects received 0.05 mg/70 kg and another 10 were given 0.1 mg/70 kg dose of fentanyl intravenously in the AM hours. Five of them had placebo trials. A dose of 0.05 mg/70 kg fentanyl was administered to patients with SMD (n = 10) and TTM (n = 12). Serial blood sampling was performed for prolactin measurements. Fentanyl elevated plasma prolactin in a dose-dependent manner. Patients with skin picking, but not with hair pulling, showed significantly increased responses. This finding supports the involvement of endogenous opioids in the pathomechanism of serious SIB.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Progress in Neuro-Psychopharmacology and Biological Psychiatry. - 26 : 5 (2002), p. 909-912. -
További szerzők:Arató Mihály
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
DOI
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8.

001-es BibID:BIBFORM034459
035-os BibID:WOS:A1997WU64600008 PMID:9133751
Első szerző:Tracy, Kathlene
Cím:Interrater reliability issues in multicenter trials, part I : theoretical concepts and operational procedures used in Department of Veterans Affairs Cooperative Study #3941 / Tracy, K., Adler, L. A., Rotrosen, J., Edson, R., Lavori, P., Gowda, S., Mukherjee, S., Williams, B., Duncan, E., Schwartz, M., Hitzemann, R., Frecska, E., Manicone, P., Caroff, S., Campbell, C., Havey, J., Casey, D., Hoffman, W., Hansen, T., Brundage, T., Hixs, M., Hanna, M., Lohr, J., Browning, J., Kanof, P., Fain, R., Krystal, J., DSouza, D. C., Damon, D., Marder, S. S., Ames, D., Ross, D., Doorack, J., Hitzemann, R., Lohr, J., Haakenson, C., Miller, M.
Dátum:1997
ISSN:0006-3223
Megjegyzések:This article describes a standardized method for establishing and maintaining desired levels of interrater reliability (IRR) in multicenter trials. The procedure involves six steps: distribution of procedural guides, distribution of an introduction tape, initial distribution of patient interviews to rate, training at the study kickoff meeting, ongoing IRR monitoring, and group training throughout the study. This method is being used in a national Veterans Affairs Cooperative Study (CS #394), involving nine sites to examine the treatment effects of vitamin E on tardive dyskinesia. The six-step standardized process allowed for early detection of areas of concern in assessment administration. When comparing intraclass correlation coefficients (ICCs) at different points in the initial training, the Barnes Akathisia Scale and Anchored Brief Psychiatric Rating Scale reliability improved from 0.68 to 0.74 and from 0.54 to 0.87, respectively. After analyzing the ratings collected prior to the start of CS #394, data were collected to conduct the first check on Abnormal Involuntary Movement Scale (AIMS) IRR during enrollment; the estimated ICC for the AIMS had decreased from 0.87 to 0.60. Raters were instructed to re-assess the subjects from the first videotape on the AIMS and received additional training. The re-rating indicated very good reliability, 0.84, IRR was measured once for the Global Assessment of Functioning Scale resulting in an ICC of 0.90. The companion article (Part II: Edson et al. 1997, page 59 of this issue) describes the statistical procedures used to measure IRR.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
külföldön készült közlemény
Megjelenés:Psychopharmacology Bulletin. - 33 : 1 (1997), p. 53-57. -
További szerzők:Adler, Lenard A. Rotrosen, John Edson, Robert Lavori, Philip Gowda, S. Mukherjee, Subhendu Williams, B. Duncan, E. Schwartz, M. Hitzemann, Robert Frecska Ede (1953-) (pszichiáter) Manicone, P. Caroff, Stanley Campbell, Cabrina Havey, J. Casey, D. Hoffman, W. Hansen, T. Brundage, T. Hixs, M. Hanna, M. Lohr, J. Browning, J. Kanof, P. Fain, R. Krystal, J. DSouza, D. C. Damon, D. Marder, S. S. Ames, D. Ross, David Doorack, J. Hitzemann, R. Lohr, James Haakenson, C. Miller, M.
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