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001-es BibID:	BIBFORM084241
Első szerző:	Takács Péter (szülész-nőgyógyász)
Cím:	The effect of oral zinc supplementation on cervicovaginal lavage fluid zinc level / Takacs Peter, Damjanovich Peter, Sipos Attila Gergely, Kozma Bence
Dátum:	2020
ISSN:	0301-2115
Megjegyzések:	Objectives: To investigate the effect of oral zinc supplementation on cervicovaginal lavage fluid (CVL) zinc level in pre and postmenopausal women. Study design: A prospective interventional cohort study was carried out by the enrollment of twelve premenopausal and ten postmenopausal women without significant gynecological conditions. Women received daily oral supplementation with 30?mg of zinc for two weeks. Clinical and demographic variables were stored in a dedicated database. Vaginal Health Index was calculated, and vaginal cytology was obtained. CVL and serum samples were collected in a standardized fashion before and after completion of the oral supplementation. Zinc and copper levels were measured by inductively coupled plasma optical emission spectrometry. Paired t-test was used to compare the before and after treatment results. Results: Serum zinc levels increased significantly both in the pre and postmenopausal women (0.88???0.17 vs. 1.06???0.23, p?<?0.01 and 0.83???0.24 vs. 0.96???0.33, p?<?0.01) after two weeks of daily oral zinc supplementation. CVL zinc level was significantly higher in the premenopausal group compared to the postmenopausal group before and after supplementation (0.13???0.05 vs. 0.06???0.04, p?<?0.01 and 0.10???0.03 vs. 0.05???0.01, p?<?0.01). Zinc supplementation had no significant impact on the CVL zinc level in either group. Neither serum nor CVL copper levels were affected by the zinc supplementation. There was no significant correlation between serum and CVL zinc or copper levels. Conclusion: Daily oral supplementation with 30?mg of zinc had no significant impact on CVL zinc level despite a significant rise in serum zinc level.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Zinc Cooper Cervicovaginal lavage Vaginal Health Index Maturation value
Megjelenés:	European Journal Of Obstetrics Gynecology And Reproductive Biology. - 248 (2020), p. 106-109. -
További szerzők:	Damjanovich Péter Gábor (1985-) (szülész-nőgyógyász) Sipos Attila Gergely (1990-) (szülész-nőgyógyász) Kozma Bence (1982-) (szülész-nőgyógyász)
Pályázati támogatás:	GINOP-2.1.1-15-2016-00783 GINOP
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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