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001-es BibID:BIBFORM112741
Első szerző:Hashmi, Amna (orvostanhallgató)
Cím:Clinical significance of normo-hydration state in peritoneal dialysis patients / Amna Hashmi, Réka P. Szabó, István Varga, László Kardos, József Balla
Dátum:2023
Megjegyzések:Background and Aims The assessment of fluid status in dialysis patients is of paramount importance. Managing persistent volume overload and instability during dialysis is a significant challenge, with concomitant symptomatic and asymptomatic intradialytic hypotension (IDH) that results in dialysis-induced myocardial ischemia (cardiac stunning) and long patient recovery times.Our aim was to estimate the status of hydration in our peritoneal dialysis population by body composition monitoring (BCM) device to modify our pharmacological and dialysis policy and to evaluate echocardiographic parameters of the RV functions in patients with end-stage renal disease (ESRD) undergoing PD. Method We used a Fresenius Body Composition Monitor (BCM), a whole-body bioimpedance spectroscopy (50 frequencies, 5?1,000 kHz), to assess the body composition of 35 patients on peritoneal dialysis in our centre..We measured body weight, 24 h diuresis and performed a BCM session. Analysed results of echocardiography focused on RV (tricuspid annular plane systolic excursion (TAPSE). As per statistics, comparisons between 2 groups done by students t test, Mann Whitney U test or Wilcoxon test. Correlation between data was done by Pearson or spearman correlation. And lastly categorical variables were assessed by fisher's exact, and Chi squared test. Results Average age was 47 years old (SD 9,45 t-test p = 0,1154:). Gender distribution was 54,3% of our patients were female. 8,6% of our patients were anuric, 91,4% had residual urine (more than 1 litre). TAPSE value were average 23,17 mm (?4,5).We measured over-hydration in 8 cases by BCM that followed dialysis policy modification. In 8 PD patients we measured more than 2 L volume overload (VO) with BCM followed by dialysis policy modification (fluid intake restriction, diuretic dose increasing, frequent solution exchange). Conclusion Our data raised the importance of regular echocardiography to identify it. More attention should be focused on improving BP and volume control and identifying treatment strategies that effectively lower further deterioration in PD patients.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:Nephrology Dialysis Transplantation. - 38 : Supplement_1 (2023), p. 1548. -
További szerzők:P. Szabó Réka (1979-) (orvos) Varga István (1967-) (kardiológus, aneszteziológus) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Balla József (1959-) (belgyógyász, nephrológus)
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001-es BibID:BIBFORM102226
Első szerző:Hashmi, Amna (orvostanhallgató)
Cím:Relevance of Proteinuria and Donor Specific Antibody in Kidney Transplanted Recipients and Allograft Outcomes / Amna Hashmi, Nóra Klenk, László Bidiga, László Kardos, Balázs Áron Nemes, József Balla, Réka P. Szabó
Dátum:2022
ISSN:0931-0509
Megjegyzések:BACKGROUND AND AIMS The onset of proteinuria in renal allograft recipients is a frequent complication that may be associated with an increased risk of graft failure and mortality. Our aim was to research if proteinuria effects is independent from donor specific antibody (DSA) for transplant graft survival and the changes of proteinuria response to therapy in ABMR group. METHOD 85 transplanted patients were enrolled in our study and followed up till 31 October 2020 or till death, or date of return to dialysis. We created three groups: ABMR group (n = 19, biopsy proven antibody mediated rejection), ABMRDSApos positive group (n = 14) ABMRDSAneg (n = 5), DSA negative group with stabile kidney function without rejection as a reference (n = 52). Differences in patient, donor and transplant characteristics between DSA positive and negative groups were assessed by Fishers exact test for categorical variables. Death censored graft loss was assessed by Kaplan Meier analysis with log risk statistics. RESULTS Proteinuria decrease after treatment in ABMR group (P = 0.0009). Graft failure's frequency increase every 10 mg/mmol elevation of proteinuria means 7% elevation (hazard ratio: 1.07%). Before treatment nephrotic proteinuria was found in group AMBRDSApoz 21%, 14,29% in group ABMR DSAneg 1,92% in reference group. Estimated 3-year graft survival was 87, 5% in ABMR group, 93% in DSA pos group, and 100% in DSA negative group (log-rank probe P = 0.0666). CONCLUSION The presence of DSA increases graft loss but it is independent to proteinuria. Therapy refractory proteinuria state represents worse graft survival.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:Nephrology Dialysis Transplantation. - 37 : 3 (2022), p. i689. -
További szerzők:Klenk Nóra (1967-) (belgyógyász, nefrológus) Bidiga László (1977-) (patológus) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Nemes Balázs Áron (1969-) (sebész) Balla József (1959-) (belgyógyász, nephrológus) P. Szabó Réka (1979-) (orvos)
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Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM113150
Első szerző:Kuszkáné File Ibolya (orvos)
Cím:Anca associated vasculitis and covid / Ibolya File, Csilla Markóth, Reka P. Szabo, Jozsef Balla, László Bidiga, János Mátyus
Dátum:2023
ISSN:0931-0509
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:Nephrology Dialysis Transplantation. - 38 : S1 (2023), p. i1264. -
További szerzők:Markóth Csilla (1984-) (belgyógyász, nephrológus) P. Szabó Réka (1979-) (orvos) Balla József (1959-) (belgyógyász, nephrológus) Bidiga László (1977-) (patológus) Mátyus János (1957-) (belgyógyász, nephrológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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