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1.

001-es BibID:BIBFORM072101
035-os BibID:(WoS)000408790300004 (Scopus)85027980350
Első szerző:Berindán Krisztina (hallgató)
Cím:Ophthalmic Findings in Patients After Renal Transplantation / Berindán K., Nemes B., Szabó R. P., Módis L.
Dátum:2017
ISSN:0041-1345
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
ophtalmic findings
renal transplantation
Megjelenés:Transplantation Proceedings. - 49 (2017), p. 1526-1529. -
További szerzők:Nemes Balázs Áron (1969-) (sebész) P. Szabó Réka (1979-) (orvos) Módis László (1964-) (szemész szakorvos, kontaktológus)
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2.

001-es BibID:BIBFORM083133
035-os BibID:(WoS)000500179300049 (Scopus)85065488059
Első szerző:Bíró Benjámin
Cím:Regulatory T Cells in the Context of New-Onset Diabetes After Renal Transplant : a Single-Center Experience / Biró B., Szabó R. P., Illésy L., Balázsfalvi N., Szőllősi G. J., Baráth S., Hevessy Z., Nemes B.
Dátum:2019
ISSN:0041-1345
Megjegyzések:Background. New-onset diabetes mellitus after transplant (NODAT) is a well-known complication of renal transplant that severely affects graft and patient survival. It is necessary to explore further risk factors and reveal the underlying pathomechanism. Methods. Renal transplants performed between January 2010 and June 2018 were involved. Exclusion criteria were the recipient age younger than 18 years, follow-up period less than 6 months, and patients with diabetes at the time of transplant. Only primary kidney transplants were involved in our study, which totaled 223 cases. Besides donor and recipient demographic data, the type of immunosuppression, the average fasting glucose level, and T-subset profiles were compared. Results. Of 223 cases there were 33 patients (14.8%) with NODAT (17 female; mean age, 54.2 [SD, 10.3] years; mean body mass index [calculated as weight in kilograms divided by height in meters squared], 27.8 [SD, 5.1]; mean follow-up, 43.3 [SD, 25.5] months). The control group consisted of 190 patients. The average fasting blood glucose level was higher in the NODAT group vs the control group (P < .001). The average fasting blood glucose level above diabetic threshold ( 7 mmol/L) was in association with a 6-fold higher risk of NODAT (odds ratio, 5.86; 95% CI, 2.46e13.97; P < .001). Absolute value of CD4?CD25brightCD127dim regulatory T cells was lower in the NODAT group at the first month after transplant (P ? .048) Immunosuppressive protocol and survival data did not differ. Conclusions. Intensive management of the carbohydrate excursions during the early post-transplant period may decrease the incidence of NODAT. Further investigations will be required to decide whether the reduced CD4?CD25brightCD127dim/regulatory T-cell count contributes the development of NODAT
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
New-Onset Diabetes, kidney trasnplantation
kidney transplantation
kidney transplant, T regulatory cells
transplantation
Megjelenés:Transplantation Proceedings. - 51 : 4 (2019), p. 1234-1238. -
További szerzők:P. Szabó Réka (1979-) (orvos) Illésy Lóránt (1991-) (sebész) Balázsfalvi Norbert Szőllősi Gergő József (1991-) (népegészségügyi ellenőr, népegészségügyi szakember) Baráth Sándor (1977-) (biológus) Hevessy Zsuzsanna (1966-) (laboratóriumi szakorvos) Nemes Balázs Áron (1969-) (sebész)
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3.

001-es BibID:BIBFORM093270
035-os BibID:(WoS)000668604400008 (Scopus)85103706436
Első szerző:Daragó Andrea (orvos, kardiológus)
Cím:Effects of Kidney Transplantation on Valvular Heart Diseases / Daragó Andrea, Szabó Eszter, Barkó Dorina, Schwegler Gerda, Szabó Réka P., Nagy Attila Csaba, Nemes Balázs
Dátum:2021
ISSN:0041-1345
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Transplantation Proceedings. - 53 : 5 (2021), p. 1433-1438. -
További szerzők:Szabó Eszter Barkó Dorina Schwegler Gerda P. Szabó Réka (1979-) (orvos) Nagy Attila Csaba (1981-) (megelőző orvostan és népegészségtan szakorvos, epidemiológus) Nemes Balázs Áron (1969-) (sebész)
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4.

001-es BibID:BIBFORM073221
035-os BibID:(WoS)000408790300002 (Scopus)85028024460
Első szerző:Illés Amanda (egészségpszichológus)
Cím:Patient Attitudes Toward Transplantation as Preferred Treatment Modality in Different Stages of Renal Disease / A. Illés, A. Bugán, S. Kovács, E. Ladányi, J. Szegedi, B. József, R. P. Szabó, B. Nemes
Dátum:2017
ISSN:0041-1345
Megjegyzések:ObjectiveKidney transplantation is generally considered to be the best treatment for end-stage renal disease. Not every patient can be operated, but many of suitable patients refuse this possibility. We aimed to explore the attitudes of patients with chronic kidney disease towards renal replacement therapies to recognize motives, thoughts, and feelings concerning accepting or refusing the treatment. We studied the attitudes towards the illness and the treatment, the appearance of depression, and the disease burden during different stages of the disease.MethodsFor this study we implemented a questionnaire that we developed (which has been described in an earlier publication of this journal) with 99 pre-dialysis patients, 99 dialysis patients, and 87 transplantation patients. We completed the attitude questionnaire designed by our team to include disease burden and depression questionnaires.ResultsWe used discriminant analysis to describe different stages of the disease. There was a significant difference in the following factors between the three patient groups: accepting the new kidney, lack of confidence in transplantation therapy, fear of surgery, accepting self-responsibility in recovery, dependency on the transplanted kidney, confidence in recovery, subjective burden of dialysis, and denial of personal responsibility in maintaining the transplanted kidney. Significant differences were also detected in these three groups regarding the level of depression and disease burden: we measured the highest value among the dialysis patients, and the lowest value among the pre-dialysis patients. Comparing patients accepting and refusing transplantation, we found a correlation between the refusal of transplantation and the attitudes towards the illness and treatment.ConclusionsMost patients remain unmotivated to change treatment modality and refuse transplantation. Misbelief about transplantation shows a correlation with the motive of refusal. Dissemination of information may facilitate a change in the situation.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
veseátültetés
pszichológia
attitűd
Megjelenés:Transplantation Proceedings. - 49 : 7 (2017), p. 1517-1521. -
További szerzők:Bugán Antal (1948-) (pszichológus, klinikai szakpszichológus, pszichoterapeuta) Kovács Sándor (1978-) (matematika tanár) Ladányi Erzsébet Szegedi János József B. P. Szabó Réka (1979-) (orvos) Nemes Balázs Áron (1969-) (sebész)
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5.

001-es BibID:BIBFORM078819
035-os BibID:(WoS)000500179300060 (Scopus)85065483146
Első szerző:Illésy Lóránt (sebész)
Cím:Non-Hodgkin Lymphoma in a Kidney Transplant Patient : a Case Report / Lóránt Illésy, Réka P. Szabó, Dávid Ágoston Kovács, Roland Fedor, Balázs Nemes
Dátum:2019
ISSN:0041-1345
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Transplantation Proceedings. - 51 : 4 (2019), p. 1286-1288. -
További szerzők:P. Szabó Réka (1979-) (orvos) Kovács Dávid Ágoston (1982-) (sebész) Fedor Roland (1975-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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6.

001-es BibID:BIBFORM073245
035-os BibID:(WoS)000386317900073 (Scopus)84992391414
Első szerző:Illésy Lóránt (sebész)
Cím:Bacterial Infections After Kidney Transplantation : a Single-Center Experience / L. Illesy, M. Szabo-Pap, F. Toth, G. Zadori, L. Zsom, L. Asztalos, R. P. Szabo, R. Fedor, B. Nemes
Dátum:2016
ISSN:0041-1345
Megjegyzések:Bacterial infections significantly affect graft loss and mortality after kidney transplantation (KT). We reviewed the frequencies, risk factors, and sources of bacterial infections after KT and their impact on graft and patient survivals. METHODS: The data of 154 kidney recipients who underwent transplantation from 2010 to 2015 were explored. Donor, recipient, and surgical parameters were collected, and source, type, and frequency of infectious complications, number of infective episodes, multidrug-resistant (MDR) bacteria, and the bacterial spectrum were established. RESULTS: The most common infection was urinary tract infection, which is in line with the literature. Out of the 154 recipients, 72.1% (n = 111) had at least 1 occasion of a bacterial infection episode with clinical symptoms. It occurred 0-43 months (mean, 19.5 mo) after transplantation. Ninety-three KT recipients (67.9%) developed 274 episodes of infection in the postoperative 1st year (1.8 episodes/patient/y), and 42 patients had admission to the hospital ward (5.2 d/patient/y). MDR was detected in 19.8% of the infections. CONCLUSIONS: A bacterial infection had no significant impact on survival by itself. However, in case of sepsis graft and patient survivals were lower compared with normal control subjects.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Transplantation Proceedings. - 48 : 7 (2016), p. 2540-2543. -
További szerzők:Szabó-Pap Marcell Tóth F. Zádori Gergely (1983-) (sebész) Zsom Lajos (1968-) (belgyógyász, nefrológus) Asztalos László (1951-) (sebész) P. Szabó Réka (1979-) (orvos) Fedor Roland (1975-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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7.

001-es BibID:BIBFORM073248
035-os BibID:(WoS)000408790300003 (Scopus)85027996499
Első szerző:Illésy Lóránt (sebész)
Cím:Autosomal Dominant Polycystic Kidney Disease Transplant Recipients After Kidney Transplantation : a Single-center Experience / L. Illesy, D. Á. Kovács, R. P. Szabó, A. B. L. Asztalos, B. Nemes
Dátum:2017
ISSN:0041-1345
Megjegyzések:Kidney transplantation is indicated for end-stage renal disease. Autosomal dominant polycystic kidney disease (ADPKD) causes structural degeneration of the kidney and eventually becomes end-stage renal disease. ADPKD patients usually have several renal and nonrenal complications. We analyzed our kidney transplantation activities between 1991 and 2010 regarding ADPKD. We followed up with patients to December 31, 2016. Data were collected as patient and graft survival rates, the prevalence of polycystic manifestation of the gastrointestinal tract and other organs, and the attendance of urinary tract infection. Among the 734 kidney transplantations, 10.9% (n = 80) had an ADPKD. Four patients (5%) had diverticulum perforation. The prevalence of post-transplantation urinary tract infection was higher in ADPKD patients (55.9%) compared to non-ADPKD patients (44.1%). The 1-, 3-, and 5-year overall survival rates in ADPKD recipients versus non-ADPKD patients are 77.5%, 70.0%, and 67.5% versus 86.4%, 83.0%, and 80.1%, respectively. Patients with ADPKD were transplanted at an elder age compared to others (median: 47.5 years vs. 39.9 years). Female patients had longer graft survival times than males. ADPKD implies multiple cystic degeneration of the kidneys; however, it can cause structural degeneration in other organs. It is typical for ADPKD patients to have an acute abdominal-like syndrome. Immunosuppressive drugs can hide the clinical picture, which makes early diagnosis difficult.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Transplantation Proceedings. - 49 : 7 (2017), p. 1522-1525. -
További szerzők:Kovács Dávid Ágoston (1982-) (sebész) P. Szabó Réka (1979-) (orvos) Asztalos László (1951-) (sebész) Nemes Balázs Áron (1969-) (sebész)
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8.

001-es BibID:BIBFORM079170
035-os BibID:(WoS)000500179300051 (Scopus)85065488320
Első szerző:Kovács Dávid Ágoston (sebész)
Cím:Surgical Treatment of Hyperparathyroidism After Kidney Transplant / D. Á. Kovács, R. Fedor, L. Asztalos, M. Andrási, R. P. Szabó, Zs. Kanyári, S. Barna, B. Nemes, F. Győry
Dátum:2019
ISSN:0041-1345
Megjegyzések: Chronic renal impairment is often associated with complex bone disorders. Improvement of secondary hyperparathyroidism (HPT) is expected after kidney transplant (KT) if the glomerular filtration rate is normalized. Patients and Methods There were 888 KTs performed between 1996 and 2017 at our department. A total of 558 general patients have been operated on for HPT during the same period. The 2 populations had a common part: out of the 558, a total of 69 (12.4%) were in end-stage renal failure when operated on because of secondary HPT. That also means that 7.8% of all KTs were associated with HPT. Retrospective, single-center analysis was performed using the patients' medical records. The aim of our study was to analyze the results of parathyroidectomies after KT. Results Parathyroid surgery was performed on 19 patients (2.14%) because of HPT after KT. The applied surgical technique was total parathyroidectomy with autotransplant in 6 cases, subtotal parathyroidectomy in 3 cases, and selective parathyroidectomy in 10 cases. In all cases, histology revealed benign disease. Complications were observed in 10 cases (52%); there were 6 cases of postoperative hypocalcaemia (31.58%), 1 case of transient laryngeal recurrent nerve paresis (5.26%), and 6 cases of recurrent HPT (31.58%). Summary The first step of HPT management is calcimimetic drug treatment. It is essential to prevent possible complications with regular laboratory monitoring. If the proper conservative therapy is refractory or severe in complications, surgery should be chosen. If the patient is already waiting for a KT, it is worth performing the parathyroid surgery before KT. Close collaboration with endocrinologists and nephrologists is needed to achieve successful therapy.
Tárgyszavak:Orvostudományok Klinikai orvostudományok konferenciacikk
folyóiratcikk
hyperparathyroidisim
kidney transplant
Megjelenés:Transplantation Proceedings. - 51 : 4 (2019), p. 1244-1247. -
További szerzők:Fedor Roland (1975-) (sebész) Asztalos László (1951-) (sebész) Andrási M. P. Szabó Réka (1979-) (orvos) Kanyári Zsolt (1964-) (orvos) Barna Sándor (1982-) (kutató orvos) Nemes Balázs Áron (1969-) (sebész) Győry Ferenc (1964-) (sebész)
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9.

001-es BibID:BIBFORM093625
035-os BibID:(WoS)000668604400007 (Scopus)85104453340
Első szerző:Nemes Balázs Áron (sebész)
Cím:T-cell Subset Profile in Kidney Recipients of Extended or Standard Donors / Balázs Nemes, Réka P. Szabó, Dávid Péntek, Ildikó Nagy, Gergely Ivády, Bettina Kárai, Eszter Szánthó, Zsuzsa Hevessy, Sándor Sipka, Gergő J. Szőllősi, Sándor Baráth
Dátum:2021
ISSN:0041-1345
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Transplantation Proceedings. - 53 : 3 (2021), p. 1423-1432. -
További szerzők:P. Szabó Réka (1979-) (orvos) Péntek Dávid Nagy Ildikó Ivády Gergely (1979-) (laboratóriumi szakorvos) Kárai Bettina (1984-) (orvos) Szánthó Eszter (laboratóriumi szakorvos jelölt) Hevessy Zsuzsanna (1966-) (laboratóriumi szakorvos) Sipka Sándor (1945-) (laboratóriumi szakorvos) Szőllősi Gergő József (1991-) (népegészségügyi ellenőr, népegészségügyi szakember) Baráth Sándor (1977-) (biológus)
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10.

001-es BibID:BIBFORM078866
035-os BibID:(WoS)000500179300046 (Scopus)85065477875
Első szerző:Nemes Balázs Áron (sebész)
Cím:T Cell Subset Profile and Appearance of Donor-specific Antibodies in Primary and Retransplanted Kidney Recipients / Nemes B., Barta A., Ivády G., Kárai B., Szánthó E., Hevessy Z., P. Szabó R., Szilvási A., Sipka S., Baráth S.
Dátum:2019
Megjegyzések:Accelerated antibody-mediated rejection is a major challenge after kidney transplantation. While the clinical course, diagnosis, and treatment of cell-mediated acute rejection is agreed upon and has been successfully performed, the antibody-mediated rejection remains a problem. Biopsies cannot be repeated several times, are not always representative, and are refused by many patients. Analysis of T-cell subsets and donor-specific antibodies (DSAs) might be an additive diagnostic tool in the case of kidney transplantation.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Transplantation Proceedings. - 51 : 4 (2019), p. 1215-1225. -
További szerzők:Barta Aliz Ivády Gergely (1979-) (laboratóriumi szakorvos) Kárai Bettina (1984-) (orvos) Szánthó Eszter (laboratóriumi szakorvos jelölt) Hevessy Zsuzsanna (1966-) (laboratóriumi szakorvos) P. Szabó Réka (1979-) (orvos) Szilvási Anikó (1977-) (molekuláris biológus) Sipka Sándor (1945-) (laboratóriumi szakorvos) Baráth Sándor (1977-) (biológus)
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11.

001-es BibID:BIBFORM061873
Első szerző:P. Szabó Réka (orvos)
Cím:Cardiovascular Screening and Management Among Kidney Transplant Candidates in Hungary / Szabó, R. P., Varga, I., Balla, J., Zsom, L., Nemes, B.
Dátum:2015
ISSN:0041-1345
Megjegyzések:Introduction. Cardiovascular disease is a major cause of morbidity and mortality in endstage renal disease patients on dialysis and the most common cause of death in the immediate post-transplantation period. The aim of our study was to describe a novel approach of cardiovascular screening and management of dialysis patients evaluated for the transplant waiting list. Methods. Twenty-eight patients with end-stage renal disease put on the waiting list between July 2013 and July 2014 were subjected to a prespecified cardiovascular screening protocol utilizing noninvasive and/or invasive tests. Patients were subsequently divided into 3 strata in terms of their estimated cardiovascular risk. Each of these groups were then prescribed interventions aiming to improve their cardiovascular condition. Results. According to our prespecified protocol of cardiovascular screening studies, 15 (54%) patients were identified as low, 5 (18%) as intermediate, and 8 (28%) as high risk. Four (14%) patients were current smokers. In the low-risk group, we initiated a patient education program involving counseling on regular exercise such as swimming or cycling to improve their functional capacity. In the high-risk group revascularization was done in 5 cases (63%), including 3 percutaneous transluminal coronary angioplasties (PTCA) with stents for single-vessel disease, and coronary artery bypass graft surgeries (CABG) for triple-vessel disease in 2 cases. In the medium-risk group medical management was opted for, including introduction of beta-blockers, inhibitors, statins, and ezetimibe, as well as efforts to optimize anemia management, indices of bone-mineral disease, and fluid status. Conclusion. In our regional transplant program, we introduced a comprehensive multidisciplinary approach to treat potential transplant candidates according to cardiovascular risk stratification based on a prespecified screening protocol. Further studies are needed to correlate this novel strategy with post-transplantation outcomes.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
vascularis kalcifikáció
krónikus veseelégtelenség
oxidatív stressz
oxidált LDL
Megjelenés:Transplantation Proceedings 47 : 7 (2015), p. 2192-2195. -
További szerzők:Varga István (orvos) Balla József (1959-) (belgyógyász, nephrológus) Zsom Lajos (1968-) (belgyógyász, nefrológus) Nemes Balázs Áron (1969-) (sebész)
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