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001-es BibID:BIBFORM103807
035-os BibID:(scopus)85083568169 (cikkazonosító)9059665
Első szerző:Deidda, Daniel
Cím:Validation of SPECT-CT image reconstruction for the Mediso AnyScan SCP scanner in STIR / Daniel Deidda, Benjamin A. Thomas, Kelley Ferreira, Warda Heetun, Attila Forgacs, Brian F. Hutton, Kris Thielemans, Andrew P. Robinson
Dátum:2019
Megjegyzések:Single photon emission tomography (SPECT) is widely used in clinical practice for a large number of diagnostic applications. However, different hospitals might use different scanners containing different hardware and software technologies, therefore making reproducibility of results a hard task. The aim of this work is to establish the basis for a tool able to include different clinical scanner models to facilitate inter-comparison of activity measurements across different institutions. We used the open source software for tomographic image reconstruction (STIR) and implemented functionalities to read, process and reconstruct the data from the Mediso AnyScan SCP scanner. In particular, the triple energy window method for scatter estimation, a method to re-scale the CT Hounsfield units in attenuation coefficient units (cm -1 ), SPECT normalisation functionalities and list mode (LM) functionalities were implemented and tested. 3D printed phantom data, with organ inserts filled with 177 Lu, and a 99m Tc clinical bone study were reconstructed using the implemented corrections and different anatomically-guided algorithms. The effect of the aforementioned correction was studied using ROI analysis and line profiles, whereas visual comparison was carried out between the reconstructed images with the vendor software and with STIR. Moreover, we demonstrated the feasibility of SPECT image reconstruction using the CT and iterative SPECT image estimates as prior information. Finally, a run time performance study showed that, when using multiple cores, an acceleration of a factor 2.7 is achieved for OSEM and around 2 for the other algorithms which involved more image-based operations. The availability of such tool will make SPECT research applications more accessible and reproducible.
Tárgyszavak:Orvostudományok Egészségtudományok előadáskivonat
könyvrészlet
Megjelenés:IEEE Nuclear Science Symposium and Medical Imaging Conference. - p. 1-4. -
További szerzők:Thomas, Ben Ferreira, Kelley Heetun, Warda Forgács Attila (1985-) (fizikus) Hutton, Brian F. Thielemans, Kris Robinson, Andrew
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001-es BibID:BIBFORM102721
035-os BibID:(Scopus)85137125116
Első szerző:Képes Zita (orvos)
Cím:Initial clinical experience with dedicated multi-pinhole (MPH) collimator for 99mTc-HMPAO brain perfusion SPECT / Zita Képes, Kornél Kukuts, Attila Oszlánszki, Iván Mihovk, Áron Krizsán, Sándor Barna, Andrew Robinson, Daniel Deidda, János Mester, József Varga, Ildikó Garai, Attila Forgács
Dátum:2022
ISSN:1790-5427
Megjegyzések:Abstract Objective: Dedicated multi-pinhole (MPH) collimators have been successfully tested in selected clinical investigations. The aim of our work was to report initial experiences with an MPH collimator set designed for brain perfusion single photon emission tomography (SPECT). Methods: Ten patients underwent sequential technetium-99m-hexamethylpropyleneamineoxime (99mTc-HMPAO) SPECT with a dual-head SPECT camera equipped with conventional low-energy parallel hole collimators (LEHR), and with a triple-head system equipped with MPH collimators. Low-energy parallel hole collimators data were reconstructed by filtered back projection (FBP), ordered subset expectation maximization (OSEM), software for tomographic image reconstruction (STIR). In addition, both the parallel hole data and MPH data were reconstructed by Tera-TomoTM 3D iterative reconstruction denoted LEHR_TT3D and MPH_TT3D, respectively. Five medical experts visually compared the reconstructed images of the five data sets and defined a ranking sequence from the lowest (1) to the highest (5) image quality. Results were compared using the Friedman test. P values below 0.05 were considered significant. Results: Low-energy parallel hole collimators acquisition resulted in 5 million, while MPH acquisition in 13 million total counts with 30 and 34 minutes of acquisition time, respectively. Mean rank coefficients of the reconstruction methods were 1.96?0.52, 2.66?0.46, 2.86?0.60, 3.62?0.55, 3.9?0.68 for FBP, STIR, LEHR_TT3D, LEHR_OSEM, MPH_TT3D respectively. The differences between MPH_TT3D-FBP (P<0.01); MPH_TT3D-STIR (P<0.05); LEHR_OSEM-FBP (P<0.01) were significant. Conclusion: Image quality provided by MPH collimator is comparable to that provided by conventional LEHR imaging. Higher sensitivity has the potential to shorten acquisition time or to reduce the amount of administered activity.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Brain perfusion
SPECT
Multi-pinhole collimator
Reconstruction
Image quality
Megjelenés:Hellenic Journal of Nuclear Medicine. - 25 : 2 (2022), p. 143-147. -
További szerzők:Kukuts Kornél Oszlánszki Attila Mihovk Iván Krizsán Áron Krisztián (1986-) (fizikus) Barna Sándor (1982-) (kutató orvos) Robinson, Andrew Deidda, Daniel Mester János Varga József (1955-) (fizikus) Garai Ildikó (1966-) (radiológus) Forgács Attila (1985-) (fizikus)
Pályázati támogatás:National Grant No. GINOP-2.1.1-15-2015-00609
GINOP
UK National Physical Laboratory through the National Measurement System
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Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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