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001-es BibID:	BIBFORM084099
Első szerző:	Manios, Yannis
Cím:	Two-stage, school and community-based population screening successfully identifies individuals and families at high-risk for type 2 diabetes : the Feel4Diabetes-study / Yannis Manios, Christina Mavrogianni, Christina-Paulina Lambrinou, Greet Cardon, Jaana Lindström, Violeta Iotova, Tsvetalina Tankova, Fernando Civeira, Jemina Kivelä, Zoltán Jancsó, Samyah Shadid, Kaloyan Tsochev, Rocío Mateo-Gallego, Sándorné Radó, George Dafoulas, Konstantinos Makrilakis, Odysseas Androutsos, Kolozsvári László, Feel4Diabetes-study group
Dátum:	2020
ISSN:	1472-6823
Megjegyzések:	Abstract Background: The implementation of population screening and early prevention strategies targeting individuals at high-risk for type 2 diabetes (T2D) seems to be a public health priority. The current work aimed to describe the screening procedure applied in the Feel4Diabetes-study and examine its effectiveness in identifying individuals and families at high risk, primarily for T2D and secondarily for hypertension, among vulnerable populations in low to middle-income countries (LMICs) and high-income countries (HICs) across Europe. Methods: A two-stage screening procedure, using primary schools as the entry-point to the community, was applied in low socioeconomic status (SES) regions in LMICs (Bulgaria-Hungary), HICs (Belgium-Finland) and HICs under austerity measures (Greece-Spain). During the first-stage screening via the school-setting, a total of 20,501 parents (mothers and/or fathers) of schoolchildren from 11,396 families completed the Finnish Diabetes Risk Score (FINDRISC) questionnaire, while their children underwent anthropometric measurements in the school setting. Parents from the identified "high-risk families" (n = 4484) were invited to participate in the second-stage screening, including the measurement of fasting plasma glucose (FPG) and blood pressure (BP). In total, 3153 parents participated in the second-stage screening (mean age 41.1 ? 5.6 years, 65.8% females). Results: Among parents who attended the second-stage screening, the prevalence of prediabetes (as defined by impaired fasting glucose; FPG 100-125 mg/dl) and T2D (FPG > 126 mg/dl) was 23.2 and 3.0% respectively, and it was found to be higher in the higher FINDRISC categories. The percentage of undiagnosed T2D among the participants identified with T2D was 53.5%. The prevalence of high normal BP (systolic BP 130-139mmHg and/ or diastolic BP 85- 89mmHg) and hypertension (systolic BP ? 140mmHg and/ or diastolic BP ? 90mmHg) was 14 and 18.6% respectively, which was also higher in the higher FINDRISC categories. The percentage of cases not receiving antihypertensive treatment among the participants identified with hypertension was 80.3%.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Hypertension School-based Screening Type 2 diabetes Vulnerable groups
Megjelenés:	BMC Endocrine Disorders. - 20 : S1 (2020), p. 1-12. -
További szerzők:	Mavrogianni, Christina Lambrinou, Christina-Paulina Cardon, Greet Lindström, Jaana Iotova, Violeta Tankova, Tsvetalina Civeira, Fernando Kivelä, Jemina Jancsó Zoltán (1973-) (orvos, háziorvos szakorvos, foglalkozás-orvostan szakorvos) Shadid, Samyah Tsochev, Kaloyan Mateo-Gallego, Rocío Radó Sándor Istvánné (1976-) (diplomás ápoló) Dafoulas, George Makrilakis, Konstantinos Androutsos, Odysseas Kolozsvári László Róbert (1977-) (háziorvos) Feel4Diabetes-Study Group
Pályázati támogatás:	The Feel4Diabetes-intervention is registered at https://clinicaltrials.gov/ (NCT02393872; date of trial registration: March 20, 2015). Egyéb
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