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001-es BibID:BIBFORM050537
Első szerző:Nagy-Baló Edina (kardiológus)
Cím:Predictors of cerebral microembolization during phased radiofrequency ablation of atrial fibrillation : analysis of biophysical parameters from the ablation generator / Edina Nagy-Balo, Alexandra Kiss, Catherine Condie, Mark Stewart, Istvan Edes, Zoltan Csanadi
Dátum:2014
ISSN:1547-5271
Megjegyzések:Background: Pulmonary vein isolation with phased radiofrequency current and use of a pulmonary vein ablation catheter (PVAC) has recently been associated with a high incidence of clinically silent brain infarcts on diffusion-weighted MRI, and a high microembolic signal (MES) count detected by transcranial Doppler. Objective: to investigate the potential correlation between different biophysical parameters of energy delivery (ED) and MES generation during PVAC ablation.Methods: MES counts during consecutive PVAC ablations were recorded for each ED and time-stamped for correlation with temperature, power and impedance data from the GENius 14.4 generator. Additionally, catheter-tissue contact was characterized by the template deviation score, calculated by comparing the temperature curve with an ideal template representing good contact, and by the respiratory contact failure score, to quantify temperature variations indicative of intermittent contact due to respiration.Results: A total of 834 EDs during 48 PVAC ablations were analyzed. A significant incease in MES count was associated with a lower average temperature, a temperature integral over 62 ?C, a higher average power, the total energy delivered, higher respiration and template deviation scores (p<0.0001), and simultaneous ED to the most proximal and distal poles of the PVAC (p<0.0001).Conclusions: MES generation during ablation is related to different indicators of poor electrode-tissue contact, the total power delivered and the interaction between the most distal and the most proximal electrodes.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
atrial fibrillation
pulmonary vein isolation
GENius generator
PVAC catheter
cerebral microembolization
transcranial Doppler
Megjelenés:Heart Rhythm. - 11 : 6 (2014), p. 977-983. -
További szerzők:Kiss Alexandra (1987-) (általános orvos) Condie, Catherine Stewart, Mark Édes István (1952-) (kardiológus) Csanádi Zoltán (1960-) (kardiológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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