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001-es BibID:BIBFORM081263
035-os BibID:(cikkazonosító)2510875 (WOS)000492956900004 (Scopus)85068695791
Első szerző:Zaha, Dana Carmen
Cím:Recent Advances in Investigation, Prevention, and Management of Healthcare-Associated Infections (HAIs) : resistant Multidrug Strain Colonization and Its Risk Factors in an Intensive Care Unit of a University Hospital / Dana Carmen Zaha, Rita Kiss, Csaba Hegedűs, Rudolf Gesztelyi, Mariann Bombicz, Mariana Muresan, Annamaria Pallag, Miklos Zrinyi, Denes Pall, Cosmin Mihai Vesa, Otilia Micle
Dátum:2019
ISSN:2314-6133 2314-6141
Megjegyzések:Active screening for resistant multidrug strain carriers remains an important component of infection control policy in any healthcare setting indifferent of financial and logistical costs.The objective of our study was to determine the spectrum of bacterial colonization individually among intensive care unit patients. A retrospective observational study was performed in the Intensive CareUnit of Emergency Clinical CountyHospital of Oradea during 2017.Medical records of the patients were used for evaluation of source of ICU admission, previous antibiotic therapy, comorbidities, and length of hospital stay. Nasal and groin swabs for MRSA detection and rectal swabs for ESBL, VRE, and CRE detection were collected upon ICU admission of all patients in the first 24 hours and after 7 days. Swab samples were processed for isolation and identification of these resistant multidrug strains. Bacterial colonization on admission was detected in a quarter of patients included in the study. Carbapenemase-producing bacteria were the most common colonizers (21.16%). On admission, 12.06% of patients have been colonized by ESBL-producing members of the family Enterobacterales. Risk factors for colonization on admission to the ICU were chronic liver diseases and chronic renal failure for ESBL infection and chronic liver disease for CRE in male patients. Evaluation of Carmeli's score for male patients showed association only with CRE colonization. Chronic renal failure was found as risk factor for ESBL colonization in female patients. The prevalence of MRSA was 5.23% and less than 1% for VRE.There was no association between any risk factors studied and the presence of S. aureus or VRE upon admission. The 7-day ICU stay also proved to be an increased risk for ESBL and CRE infection.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Intensive Care Unit
Healthcare-Associated Infections
Megjelenés:Biomed Research International. - 2019 (2019), p. 1-9. -
További szerzők:Kiss Rita (1974-) (laboratóriumi diagnosztika szakorvos) Hegedűs Csaba (1983-) (Molekuláris biológus, Cera-Med Kft. Debrecen) Gesztelyi Rudolf (1969-) (kísérletes farmakológus) Bombicz Mariann (1987-) (gyógyszerész) Muresan, Mariana Pallag Annamária Zrínyi Miklós (kémikus) Páll Dénes (1967-) (belgyógyász, kardiológus) Vesa, Cosmin Mihai Micle, Otilia
Pályázati támogatás:EFOP-3.6.2-16-2017-00009
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