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001-es BibID:	BIBFORM079294
035-os BibID:	(cikkazonosító)e4198 (WoS)000423772400001 (Scopus)85041373987 (PMID)29404201 (PMCID)PMC5797449
Első szerző:	Csizmár Nikolett (állattenyésztő mérnök)
Cím:	Genetic analysis of the Hungarian draft horse population using partial mitochondrial DNA D-loop sequencing / Nikolett Csizmár, Sándor Mihók, András Jávor, Szilvia Kusza
Dátum:	2018
ISSN:	2167-8359
Megjegyzések:	Background The Hungarian draft is a horse breed with a recent mixed ancestry created in the 1920s by crossing local mares with draught horses imported from France and Belgium. The interest in its conservation and characterization has increased over the last few years. The aim of this work is to contribute to the characterization of the endangered Hungarian heavy draft horse populations in order to obtain useful information to implement conservation strategies for these genetic stocks. Methods To genetically characterize the breed and to set up the basis for a conservation program, in the present study a hypervariable region of the mitochrondial DNA (D-loop) was used to assess genetic diversity in Hungarian draft horses. Two hundred and eighty five sequences obtained in our laboratory and 419 downloaded sequences available from Genbank were analyzed. Results One hundred and sixty-four haplotypes and thirty-six polymorphic sites were observed. High haplotype and nucleotide diversity values (Hd = 0.954 ± 0.004; ? = 0.028 ± 0.0004) were identified in Hungarian population, although they were higher within than among the different populations (Hd = 0.972 ± 0.002; ? = 0.03097 ± 0.002). Fourteen of the previously observed seventeen haplogroups were detected. Discussion Our samples showed a large intra- and interbreed variation. There was no clear clustering on the median joining network figure. The overall information collected in this work led us to consider that the genetic scenario observed for Hungarian draft breed is more likely the result of contributions from ?ancestrally' different genetic backgrounds. This study could contribute to the development of a breeding plan for Hungarian draft horses and help to formulate a genetic conservation plan, avoiding inbreeding while.
Tárgyszavak:	Agrártudományok Állatorvosi tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Equus caballus Genetic diversity mtDNA D-loop region Hungarian draft horse
Megjelenés:	PeerJ. - 6 (2018), p. 1-17. -
További szerzők:	Mihók Sándor (1950-) (agrármérnök) Jávor András (1952-) (agrármérnök) Kusza Szilvia (1979-) (agrármérnök)
Pályázati támogatás:	EFOP-3.6.3-VEKOP-16-2017-00008 EFOP
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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