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001-es BibID:	BIBFORM101524
035-os BibID:	(cikkazonosító)949 (WoS)000801949300001 (Scopus)85129502844
Első szerző:	Borbély Katalin
Cím:	PET/MRI in the Presurgical Evaluation of Patients with Epilepsy: A Concordance Analysis / Borbély Katalin, Emri Miklós, Kenessey István, Tóth Márton, Singer Júlia, Barsi Péter, Vajda Zsolt, Pál Endre, Tóth Zoltán, Beyer Thomas, Dóczi Tamás, Bajzik Gábor, Fabó Dániel, Janszky József, Jordán Zsófia, Fajtai Dániel, Kelemen Anna, Juhos Vera, Wintermark Max, Nagy Ferenc, Moizs Mariann, Nagy Dávid, Lückl János, Repa Imre
Dátum:	2022
ISSN:	2227-9059
Megjegyzések:	The aim of our prospective study was to evaluate the clinical impact of hybrid [18F]-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ([18F]-FDG PET/MRI) on the decision workflow of epileptic patients with discordant electroclinical and MRI data. A novel mathematical model was introduced for a clinical concordance calculation supporting the classification of our patients by subgroups of clinical decisions. Fifty-nine epileptic patients with discordant clinical and diagnostic results or MRI negativity were included in this study. The diagnostic value of the PET/MRI was compared to other modalities of presurgical evaluation (e.g., electroclinical data, PET, and MRI). The results of the population-level statistical analysis of the introduced data fusion technique and concordance analysis demonstrated that this model could be the basis for the development of a more accurate clinical decision support parameter in the future. Therefore, making the establishment of "invasive" (operable and implantable) and "not eligible for any further invasive procedures" groups could be much more exact. Our results confirmed the relevance of PET/MRI with the diagnostic algorithm of presurgical evaluation. The introduction of a concordance analysis could be of high importance in clinical and surgical decision-making in the management of epileptic patients. Our study corroborated previous findings regarding the advantages of hybrid PET/MRI technology over MRI and electroclinical data.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk PET/MRI epilepsy
Megjelenés:	Biomedicines. - 10 : 5 (2022), p. 1-14. -
További szerzők:	Emri Miklós (1962-) (fizikus) Kenessey István Tóth Márton (1960-) (neurológus) Singer Júlia Barsi Péter Vajda Zsolt Pál Endre Tóth Zoltán Beyer, Thomas Dóczi Tamás Bajzik Gábor (1968-) (orvos) Fabó Dániel Janszky József Jordán Zsófia Fajtai Dániel Kelemen Anna Juhos Vera Wintermark, Max Nagy Ferenc (neurológus Kaposvár) Moizs Marianna (1964-) (orvos) Nagy Dávid Lückl János Repa Imre (1950-) (radiológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM087668
035-os BibID:	(WoS)000613505800002 (Scopus)85091897870
Első szerző:	Tollár József
Cím:	High frequency and intensity rehabilitation in 641 subacute ischemic stroke patients / Tollár József, Ferenc Nagy, Bence Csutorás, Nándor Prontvai, Zsófia Nagy, Katalin Török, Eszter Blényesi, Zsolt Vajda, Dóra Farkas, Béla E. Tóth, Imre Repa, Mariann Moizs, Dávid Sipos, András Kedves, Árpád Kovács, Tibor Hortobágyi
Dátum:	2021
ISSN:	0003-9993
Megjegyzések:	Objective To determine the effects of Exergaming on quality of life (QoL), motor, and clinical symptoms in sub-acute stroke patients. Design A pseudo randomized clinical trial, using a before-after test design. Settings University hospital setting. Participants Of 3,857 sub-acute, ischemic stroke outpatients, 680 were randomized and 641 completed the study. Interventions We determined the effects of 5x/week twice (EX2, 50 sessions, n=286) and once daily (EX1, 25 sessions, n=272) Exergaming and low-intensity standard care (CON, 25 sessions, n=83) on clinical, mobility, blood pressure (BP), and QoL outcomes. Main Outcome Measures The primary outcome: Modified Rankin Scale (mRS). Secondary outcomes: Activities of daily living (ADL), five aspects of health-related QoL(EQ-5D), Beck Depression Inventory (BDI), six-minute walk test (6MWT), Berg Balance Scale (BBS) and static balance (center of pressure, COP). Results During exercise, peak heart rate was 134, 134, and 126 b?min-1 in EX2, EX1, and CON. mRS improved similarly in EX2 (-1.8, effect size, d=-4.0) and EX1 (-1.4, d=-2.6) but more than in CON (-0.7, d=-0.6). QoL, Barthel index, Berg balance scale, six-minute walk test, and standing posturography improved in a pattern of EX2>EX1=CON. Systolic and diastolic rBP decreased more in EX2 and EX1 than CON. The intervention effects did no differ between males (n=349) and females (n=292). Conclusion Twice daily compared with once daily high-intensity Exergaming or once-daily lower intensity standard care produced superior effects on clinical and motor symptoms, BP, and QoL in male and female sub-acute ischemic stroke participants.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Virtual reality Exercise Quality of life Activities of daily living Gender
Megjelenés:	Archives Of Physical Medicine And Rehabilitation. - 102 : 1 (2021), p. 9-18. -
További szerzők:	Nagy Ferenc (neurológus Kaposvár) Csutorás Bence Prontvai Nándor Nagy Zsófia Török Katalin Blényesi Eszter Vajda Zsolt Farkas Dóra (1968-) (gyógytornász) Tóth E. Béla (1960-) (orvos) Repa Imre (1950-) (radiológus) Moizs Marianna (1964-) (orvos) Sipos Dávid Kedves András Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus) Hortobágyi Tibor
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