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001-es BibID:	BIBFORM074592
035-os BibID:	(scopus)85054932408 (wos)000440703300001
Első szerző:	Boruzs Klára (környezetkutató vegyész és MBA)
Cím:	High Inequalities Associated With Socioeconomic Deprivation in Cardiovascular Disease Burden and Antihypertensive Medication in Hungary / Boruzs Klára, Juhász Attila, Nagy Csilla, Szabó Zoltán, Jakovljevic Mihajlo, Bíró Klára, Ádány Róza
Dátum:	2018
ISSN:	1663-9812
Megjegyzések:	The wide life expectancy gap between the old and new member states of the EuropeanUnion is most strongly related to the high rate of premature mortality caused bycardiovascular diseases (CVDs). To learn more about the background of this gap,the relationship of socioeconomic status (SES) with CVD mortality, morbidity andthe utilization of antihypertensive drugs was studied in Hungary, a Central-EasternEuropean country with an extremely high relative risk of premature CVD mortality. Riskanalysis capabilities were used to estimate the relationships between SES, which wascharacterized by tertiles of a multidimensional composite indicator (the deprivation index)and CVD burden (mortality and morbidity) as well as the antihypertensive medicationsat the district level in Hungary. The excess risks caused by premature mortality fromCVDs showed a strong correlation with deprivation using the Rapid Inquiry Facility. Thedistribution of prevalence values related to these diseases was found to be similar, butin the areas of highest deprivation, where the prevalence of chronic ischaemic heartdiseases and cerebrovascular diseases was found to be higher than the national averageby 30 and 20%, the prevalence of hypertension exceeded the national average by only4%. A linear association between the relative frequency of prescriptions/redemptions anddeprivation for most antihypertensive drugs, except angiotensinogen receptor blockers,was shown. More intense screening for hypertension is proposed to improve the controlof CVDs in countries affected by high disease burden.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk antihypertensive drugs cardiovascular mortality deprivation primary care primary non-compliance prescription redemption
Megjelenés:	Frontiers in Pharmacology. - 9 (2018), p. 1-14. -
További szerzők:	Juhász Attila (1970-) (epidemiológus) Nagy Csilla (1970-) (epidemiológus, népegészségügyi szakember) Szabó Zoltán (1973-) (belgyógyász, kardiológus) Jakovljevic, Mihajlo Bíró Klára (1970-) (egészségügyi menedzsment) Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pályázati támogatás:	MTA-TKI: 2011TKI473 Egyéb GINOP-2.3.2-15-2016-00005 GINOP
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM062990
035-os BibID:	(scopus)84966746668 (wos)000372731900001
Első szerző:	Boruzs Klára (környezetkutató vegyész és MBA)
Cím:	Relationship between statin utilization and socioeconomic deprivation in Hungary / Klára Boruzs, Attila Juhász, Csilla Nagy, Róza Ádány, Klára Bíró
Dátum:	2016
ISSN:	1663-9812
Megjegyzések:	The risk of premature mortality caused by cardiovascular diseases (CVDs) is approximately three times higher in the Central Eastern European region than in high income European countries, which suggests a lack and/or ineffectiveness of preventive interventions against CVDs. The aim of the present study was to provide data on the relationship between premature CVD mortality, statin utilization as a preventive medication and socioeconomic deprivation at the district level in Hungary. As a conceptually new approach, the prescription of statins, the prescription redemption and the ratio between redemption and prescription rates were also investigated. The number of prescriptions for statins and the number of redeemed statin prescriptions were obtained from the National Health Insurance Fund Administration of Hungary for each primary healthcare practice for the entire year of 2012. The data were aggregated at the district level. To define the frequency of prescription and of redemption, the denominator was the number of the 40+-year-old population adjusted by the rates of 60+-year-old population of the district. The standardized mortality rates, frequency of statin prescriptions, redeemed statin prescriptions and ratios for compliance in relation to the national average were mapped using the ♭♭disease mapping'' option, and their association with deprivation (tertile of deprivation index as a district-based categorical covariate) was defined using the risk analysis capabilities within the Rapid Inquiry Facility. The risk analysis showed a significant positive association between deprivation and the relative risk of premature cardiovascular mortality, and a reverse J-shaped association between the relative frequency of statin prescriptions and deprivation. Districts with the highest deprivation showed a low relative frequency of statin prescriptions; however, significantly higher primary compliance (redemption) was observed in districts with the highest deprivation. Our data clearly indicate that insufficient statin utilization is strongly linked to the so-called physician-factor, i.e., a statin prescription. Consequently, statin treatment is poor and represents a significant barrier to reducing mortality, particularly among people living in highly deprived areas of the country.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk statin prescription redemption deprivation cardiovascular mortality health services research
Megjelenés:	Frontiers in Pharmacology. - 7 : 66 (2016), p. [1-9]. -
További szerzők:	Juhász Attila (1970-) (epidemiológus) Nagy Csilla (1970-) (epidemiológus, népegészségügyi szakember) Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos) Bíró Klára (1970-) (egészségügyi menedzsment)
Pályázati támogatás:	MTA-TKI: 2011TKI473 Egyéb SH/8 Egyéb Swiss Contribution Programme Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: