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001-es BibID:BIBFORM078495
035-os BibID:(cikkazonosító)427 (WoS)000466184500001 (Scopus)85067878419 (PMID)31105639
Első szerző:Horváth László (gyógyszerész)
Cím:The outcome of status epilepticus and long-term follow-up / László Horváth, István Fekete, Márk Molnár, Réka Válóczy, Sándor Márton, Klára Fekete
Dátum:2019
ISSN:1664-2295
Megjegyzések:Objective: This study was to investigate the outcome of status epilepticus (SE) associated with antiepileptic therapy during SE and in follow-up period, risk factors including age, co-morbidities, pre-existing epilepsy, and etiology in the East-Hungarian region. Methods: A prospective cross-sectional database was compiled from outpatient files between 2013 and 2017. Follow-up ended on 30.06.2018. Results: One hundred and thirty five episodes (male: 68, 50.4%) were evaluated, mean age and follow-up time being 64.1 +/- 13.9 years and 39.9 +/- 14.2 months, respectively. Of the 89 patients with pre-existing epilepsy, 34 failed to visit the outpatient unit regularly. Case fatality rate was 25.2% and 31 patients (30.7%) died after discharge due to co-morbidities; their mean survival time was 10.44 +/- 8 months. Focal, generalized and combined type epilepsies were diagnosed in 67 patients (49.6%), 47 patients (34.8%), and 21 patients (15.6%) of SE, respectively. Nine patients had non-convulsive SE (NCSE). Mean seizure-free period was 6.8 +/- 6.9 months. Patients taking carbamazepine (20.9%; OR: 0.37, 95% CI: 0.16-0.82; p = 0.018), levetiracetam (27.5%; OR: 0.51, 95% CI: 0.27-0.97; p = 0.041), or valproate (11.1%; OR: 0.18, 95% CI: 0.05-0.61; p = 0.0043) were expected to achieve seizure freedom after SE. The worst outcome was linked to advanced age, etiology, new onset status epilepticus, NCSE, and focal status epilepsy. Conclusion: This study highlights the importance of regular care and patient follow-up.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Frontiers in Neurology. - 10 : 427 (2019), p. 1-8. -
További szerzők:Fekete István (1951-) (neurológus, pszichiáter) Molnár Márk Válóczy Réka Márton Sándor (1965-) (matematikus) Fekete Klára (1978-) (neurológus)
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Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:BIBFORM114636
035-os BibID:(cikkazonosító)1254214
Első szerző:Válóczy Réka
Cím:Comparative analysis of three decades' experience in the management of pregnant women with epilepsy : a real-life scenario / Válóczy Réka, Fekete István, Horváth László, Mészáros Zsófia, Fekete Klára
Dátum:2023
ISSN:1664-2295
Megjegyzések:Introduction: People with epilepsy have to face many challenges, including regular follow-ups, the need to take antiseizure medications (ASMs), and the fear of seizures. Pregnant women with epilepsy (PWWE) are a special group with even more challenges because they are responsible for the fetus. We aimed to evaluate the change in the frequency of pregnancies over the years and the possible role of newer types of ASMs concerning this change, the shift inmedication use over three decades, and their possible impact on the outcome of the observed pregnancies. Methods: Data were retrieved from the prospective Epilepsy Database of the Outpatient Clinic at our tertiary center between 1 January 1992 and 31 December 2020. Groups were formed for comparison in time and depending on whether regular care consultation was our task. Statistical analysis was carried out using Microsoft O ce Excel 2021. Basic statistics and categorical variables were assessed using Pearson's
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
pregnancy
antiseizure medication
seizure
women with epilepsy (WWE)
Epilepsy Care
Megjelenés:Frontiers in Neurology. - 14 (2023), p. 1-11. -
További szerzők:Fekete István (1951-) (neurológus, pszichiáter) Horváth László (1973-) (gyógyszerész) Mészáros Zsófia Fekete Klára (1978-) (neurológus)
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DOI
Intézményi repozitóriumban (DEA) tárolt változat
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