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001-es BibID:BIBFORM068094
Első szerző:Centini, Gabriele
Cím:Impact of Laparoscopic Surgical Management of Deep Endometriosis on Pregnancy Rate / Gabriele Centini, Karolina Afors, Rouba Murtada, Istvan Mate Argay, Lucia Lazzeri, Cherif Youssef Akladios, Errico Zupi, Felice Petraglia, Arnaud Wattiez
Dátum:2016
Megjegyzések:Study Objective: To evaluate the impact of laparoscopic excision of lesions on deep endometriosis-related infertility. Design: Retrospective study.Setting: Endometriosis tertiary referral center (Canadian Task Force II-2).Patients: A group of 115 patients who had undergone laparoscopic surgery for infertility with histologic confirmation of deep endometriosis.Interventions: Patient medical records and operative reports were reviewed. Telephone interviews were conducted for long- term follow-up of fertility outcomes.Measurements and Main Results: Evaluation of fertility outcome after laparoscopic treatment of deep endometriosis by spontaneous conception and by assisted reproductive technology (ART) correlated with lesion number, size, and location (anterior, posterolateral, pouch of Douglas, and multiple locations). After a mean follow-up of 22 months the overall preg- nancy rate was 54.78% (n 5 63) with a live-birth rate of 42.6% (n 5 49). Among those patients given the chance to conceive spontaneously (n 5 70), the overall pregnancy rate was 60% (n 5 42): 38.5% (n 5 27) spontaneously and 21.4% (n 5 15) by ART. The removal of multiple lesions was associated with a higher pregnancy rate after surgery. When comparing isolated lesion size and disease location, there was no difference in pregnancy rate. Furthermore, those patients who underwent surgical eradication of the disease for the first time had a higher pregnancy rate (odds ratio, 4.18).Conclusion: This study demonstrates that laparoscopic excision of deep endometriosis enhances pregnancy rate, by both spontaneous conception and ART. First surgical treatment of multiple lesions was associated with higher pregnancy rates, whereas isolated lesions influenced the pregnancy rate irrespective of their location and size. Journal of Minimally Invasive Gynecology (2016) 23, 113?119 ! 2016 AAGL. All rights reserved.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Deep endometriosis
Infertility
Laparoscopic treatment
Lesion localization
Pregnancy rate
Megjelenés:Journal of Minimally Invasive Gynecology 23 : 1 (2016), p. 113-119. -
További szerzők:Afors, Karolina Murtada, Rouba Argay István Máté (1981-) (orvos) Lazzeri, Lucia Akladios, Cherif Youssef Zupi, Errico Petraglia, Felice Wattiez, Arnaud
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DOI
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001-es BibID:BIBFORM068096
Első szerző:Zupi, Errico
Cím:Nonsurgical Alternatives for Uterine Fibroids / Errico Zupi, Gabriele Centini, Lorenzo Sabbioni, Lucia Lazzeri, Istvan Mate Argay, Felice Petraglia
Dátum:2016
Megjegyzések:Uterine leiomyomata are the direct cause of a significant health- care burden for women, their families, and society as a whole. Because of the long experience with the mode of treatment, sur- gical myomectomy remains the gold standard for treating reproductive-age women; however, in the recent years, the wide evolution of less invasive approaches led to a change in the options used by the clinician to treat symptomatic fibroids.Minimally invasive procedures such as uterine artery embolization (UAE) are increasingly used to treat symptomatic fibroids. Other alternative treatments are becoming more diffuse, such as mag- netic resonanceeguided high-frequency focused ultrasound sur- gery (MRgFUS), cryomyolysis, vaginal occlusion, and laparoscopic closure of the uterine arteries. Both advantages and limitations of these techniques under development must be taken into account, but this wider range of choices is being increasingly considered for a tailored treatment.This article aims to enable health-care providers with the tools to provide the latest evidence-based care in the minimally invasive or noninvasive management of this common problem.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
fibroids
UAE
MRgFUS
cryomyolysis
nonsurgical
Megjelenés:Best Practice & Research Clinical Obstetrics and Gynaecology 34 (2016), p. 122-131. -
További szerzők:Centini, Gabriele Sabbioni, Lorenzo Lazzeri, Lucia Argay István Máté (1981-) (orvos) Petraglia, Felice
Internet cím:DOI
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