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001-es BibID:	BIBFORM100238
035-os BibID:	(cikkazonosító)847 (WoS)000755032500001 (Scopus)85124104299
Első szerző:	Freihat, Omar
Cím:	Correlation between Tissue Cellularity and Metabolism Represented by Diffusion-Weighted Imaging (DWI) and 18F-FDG PET/MRI in Head and Neck Cancer (HNC) / Freihat Omar, Zoltán Tóth, Pinter Tamas, Kedves András, Sipos Dávid, Repa Imre, Kovács Árpád, Zsolt Cselik
Dátum:	2022
ISSN:	2072-6694
Megjegyzések:	Background: This study aimed to assess the association of 18F-Fluorodeoxyglucose positronemission-tomography (18F-FDG/PET) and DWI imaging parameters from a primary tumor and their correlations with clinicopathological factors. Methods: We retrospectively analyzed primary tumors in 71 patients with proven HNC. Primary tumor radiological parameters: DWI and FDG, as well as pathological characteristics were analyzed. Spearman correlation coefficient was used to assess the correlation between DWI and FDG parameters, ANOVA or Kruskal?Wallis, independent sample t-test, Mann?Whitney test, and multiple regression were performed on the clinicopathological features that may affect the 18F- FDG and apparent-diffusion coefficient (ADC) of the tumor. Results: No significant correlations were observed between DWI and any of the 18F-FDG parameters (p > 0.05). SUVmax correlated with N-stages (p = 0.023), TLG and MTV correlated with T-stages (p = 0.006 and p = 0.001), and ADC correlated with tumor grades (p = 0.05). SUVmax was able to differentiate between N+ and N? groups (p = 0.004). Conclusions: Our results revealed a non-significant correlation between the FDG-PET and ADC-MR parameters. FDG-PET-based glucose metabolic and DWI-MR-derived cellularity data may represent different biological aspects of HNC
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Cancers. - 14 : 3 (2022), p. 1-12. -
További szerzők:	Tóth Zoltán Pintér Tamás Kedves András Sipos Dávid Repa Imre (1950-) (radiológus) Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus) Cselik Zsolt
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