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001-es BibID:BIBFORM087704
035-os BibID:(cikkazonosító)1484 (WOS)000570425700001 (Scopus)85090955102
Első szerző:Kedves András
Cím:Predictive Value of Diffusion, Glucose Metabolism Parameters of PET/MR in Patients With Head and Neck Squamous Cell Carcinoma Treated With Chemoradiotherapy / Kedves András, Tóth Zoltán, Emri Miklós, Fábián Krisztián, Sipos Dávid, Freihat Omar, Tollár József, Cselik Zsolt, Lakosi Ferenc, Bajzik Gábor, Repa Imre, Kovács Árpád
Dátum:2020
ISSN:2234-943X
Megjegyzések:Purpose: This study aims to evaluate the predictive value of the pretreatment, metabolic, and diffusion parameters of a primary tumor assessed with PET/MR on patient clinical outcomes. Methods: Retrospective evaluation was performed using PET/MR image data sets acquired using the single tracer injection dual imaging of 68 histologically proven head and neck cancer patients 4 weeks before receiving definitive chemoradiotherapy (CRT). PET/MR was performed before the CRT and 12 weeks after the CRT for response evaluation. Image data (PET and MRI diffusion-weighted imaging [DWI]) was used to specify the maximum standard uptake value, the peak lean body mass corrected, SUVmax, the metabolic tumor volume, the total lesion glycolysis (SUVmax, SULpeak, MTV, and TLG), and the mean apparent diffusion coefficient (ADCmean) of the primary tumor. Based on the results of the therapeutic response evaluation, two patient subgroups were created: one with a viable tumor and another without. Metabolic and diffusion data, from the pretreatment PET/MR and the therapeutic response, were correlated using Spearman's correlation coefficient and Wilcoxon's test. Results: After completing the CRT, a viable residual tumor was detected in 36/68 (53%) cases, and 32/68 (47%) patients showed complete remission. However, no significant correlation was found between the pretreatment parameter, ADCmean (p = 0.88), and the therapeutic success. The PET parameters, SUVmax and SULpeak, MTV, and TLG (p = 0.032, p = 0.01, p < 0.0001, p = 0.0004) were statistically significantly different between the two patient subgroups. Kedves et al. Predictive Value of 18F-FDG PET/MR Conclusion: This study found that MRI-based (ADCmean) data from FDG PET/MR pretreatment could not be used to predict therapeutic response although the PET parameters SUVmax, SULpeak, MTV, and TLG proved to be more useful; thus, their inclusion in risk stratification may also be of additional value.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
PET/MR
predictive value
SUV
MTV
TLG
ADC
clinical outcome
squamous cell carcinoma
Megjelenés:Frontiers in Oncology. - 10 (2020), p. 1-11. -
További szerzők:Tóth Zoltán Emri Miklós (1962-) (fizikus) Fábián Krisztián Sipos Dávid Freihat, Omar Tollár József Cselik Zsolt Lakosi Ferenc Bajzik Gábor (1968-) (orvos) Repa Imre (1950-) (radiológus) Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus)
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2.

001-es BibID:BIBFORM116530
035-os BibID:(WoS)001142439600001 (scopus)85177696261
Első szerző:Sipos Dávid
Cím:Reduced burnout in medical and health science students during the pandemic COVID-19 : a follow-up study of a single institution in Hungary / Sipos David, Biro Anett Anna, Busa Flora, Freihat Omar, Tollár József, Pandur Attila András, Kovács Árpád, Deutsch Krisztina, Csima Melinda Petőné
Dátum:2023
ISSN:1472-6920
Megjegyzések:Background The coronavirus pandemic has significantly impacted lives worldwide, especially of medical and health science students. In Hungary, education has been relegated to the online space, with a substantial proportion of students having to attend medical secondments. Increased stress, uncertainty, and the presence of medical secondments can have an impact on students' premature burnout. Methods In 2021, we conducted a follow-up survey among students of the University of Pécs studying medicine and health sciences in two data collection periods (from March to May and September to November). Our online questionnaire consisted of the Maslach Burnout Inventory General Survey for Students and our self-designed questionnaire. We used descriptive and paired two-sample t-tests for data analysis at a 95% confidence interval (p <= 0.05). Results We excluded from our survey respondents whose data we could not follow-up; finally, 183 students' responses were analyzed. The majority of students were female (n=148; 80.9%). Overall, there was a significant decrease in both exhaustion (EX) and cynicism (CY) scores (p=0.001; p=0.004). Female respondents had higher EX scores, but a significant decrease was observed for both genders (p?0.05). Excluding paramedic students, a significant decrease in EX scores was observed for the specialties we studied (p <= 0.05). General medicine students' CY scores decreased; physiotherapy students' profesisonal efficacy (PE) scores increased significantly (p <= 0.05). Students who were on medical secondments (n=127; 69. 4%) were found to be more affected by burnout, but in all cases, these scores significantly improved (p <= 0.05). Students serving in the National Ambulance Service (n=76; 41.5%), Hospitals (n=44; 24.0%), or both (n=7; 3.8%) had a significant decrease in their burnout score (p <= 0.05). Students who served in either a hospital or a hospital and National Ambulance Service had significantly improved CY and PE scores (p <= 0.05). Students concerned about their health had elevated EX and CY scores, which also improved (p <= 0.05).
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Student
Burnout
COVID-19
Secondment
Maslach burnout inventory general survey for students scale
Megjelenés:BMC Medical Education. - 23 : 1 (2023), p. 1-8. -
További szerzők:Biró Anett Anna Busa Flóra Freihat, Omar Tollár József Pandur Attila András Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus) Deutsch Krisztina Petőné Csima Melinda
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Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM108912
035-os BibID:(Scopus)85149300395 (WoS)000953322600001
Első szerző:Sipos Dávid
Cím:Burnout and occupational stress among Hungarian radiographers working in emergency and non-emergency departments during COVID-19 pandemic / Sipos David, Jenei Timea, Kövesdi Orsolya Liza, Novák Pál, Freihat Omar, Tollár József, Pandur Attila András, Kovács Árpád, Repa Imre, Petőné Csima Melinda
Dátum:2023
ISSN:1078-8174 1532-2831
Megjegyzések:Introduction The increased workload caused by the coronavirus pandemic may have had a significant impact on the mental health of radiographers. The aim of our study was to investigate burnout and occupational stress in radiographers working in emergency departments (ED) and non-emergency departments (NED) Methods Quantitative, cross-sectional, descriptive research was carried out among radiographers working in the public health sector in Hungary. Due to the cross-sectional nature of our survey, there was no overlap between the ED and NED groups. For data collection, we used simultaneously the Maslach Burnout Inventory (MBI), the Effort-Reward Imbalance questionnaire (ERI), and our self-designed questionnaire Results We excluded incomplete questionnaires from our survey; finally, 439 responses were evaluated. Significantly higher scores for depersonalisation (DP; 8.43 (SD=6.69) vs. 5.63 (SD=4.21) and emotional exhaustion (EE; 25.07 (SD=11.41) vs. 19.72 (SD=11.72)) were observed in radiographers working in ED (p=0.001; p=0.001) when compared to NED. Male radiographers working in ED aged 20-29 and 30-39 years with experience of 1-9 years were more affected by DP (p?0.05). Worrying about one's own health had a negative effect on DP and EE (p?0.05). Having close friend with a COVID-19 infection had a negative effect on EE (p?0.05); not being infected with coronavirus, not being quarantined and relocating within the workplace had a positive effect on personal accomplishment (PA); radiographers who were 50 years or older with 20-29 years of experience were more affected by depersonalisation (DP); and those who worried about their health had significantly higher stress scores (p?0.05) in both ED and NED settings Conclusion Male radiographers at the beginning of their careers were more affected by burnout. Employment in EDs had a negative impact on DP and EE
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
radiographer
coronavirus
MBI
ERI
emergency
mental health
burnout
stress
Megjelenés:Radiography. - 29 : 3 (2023), p. 466-472. -
További szerzők:Jenei Timea Kövesdi Orsolya Liza Novák Pál Freihat, Omar Tollár József Pandur Attila András Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus) Repa Imre (1950-) (radiológus) Petőné Csima Melinda
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Intézményi repozitóriumban (DEA) tárolt változat
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4.

001-es BibID:BIBFORM095649
035-os BibID:(cikkazonosító)699360 (WOS)000674593900001 (Scopus)85111019879
Első szerző:Sipos Dávid
Cím:Additional Value of 18F-FDOPA Amino Acid Analog Radiotracer to Irradiation Planning Process of Patients With Glioblastoma Multiforme / David Sipos, Zoltan László, Zoltan Tóth, Peter Kovács, Jozsef Tollár, Akos Gulybán, Ferenc Lakosi, Imre Repa, Arpad Kovács
Dátum:2021
ISSN:2234-943X
Megjegyzések:Purpose To investigate the added value of 6-(18F]-fluoro-L-3,4-dihydroxyphenylalanine (FDOPA) PET to radiotherapy planning in glioblastoma multiforme (GBM). Methods From September 2017 to December 2020, 17 patients with GBM received external beam radiotherapy up to 60 Gy with concurrent and adjuvant temozolamide. Target volume delineations followed the European guideline with a 2-cm safety margin clinical target volume (CTV) around the contrast-enhanced lesion+resection cavity on MRI gross tumor volume (GTV). All patients had FDOPA hybrid PET/MRI followed by PET/CT before radiotherapy planning. PET segmentation followed international recommendation: T/N 1.7 (BTV1.7) and T/N 2 (BTV2.0) SUV thresholds were used for biological target volume (BTV) delineation. For GTV-BTVs agreements, 95% of the Hausdorff distance (HD95%) from GTV to the BTVs were calculated, additionally, BTV portions outside of the GTV and coverage by the 95% isodose contours were also determined. In case of recurrence, the latest MR images were co-registered to planning CT to evaluate its location relative to BTVs and 95% isodose contours. Results Average (range) GTV, BTV1.7, and BTV2.0 were 46.58 (6-182.5), 68.68 (9.6-204.1), 42.89 (3.8-147.6) cm(3), respectively. HD95% from GTV were 15.5 mm (7.9-30.7 mm) and 10.5 mm (4.3-21.4 mm) for BTV1.7 and BTV2.0, respectively. Based on volumetric assessment, 58.8% (28-100%) of BTV1.7 and 45.7% of BTV2.0 (14-100%) were outside of the standard GTV, still all BTVs were encompassed by the 95% dose. All recurrences were confirmed by follow-up imaging, all occurred within PTV, with an additional outfield recurrence in a single case, which was not DOPA-positive at the beginning of treatment. Good correlation was found between the mean and median values of PET/CT and PET/MRI segmented volumes relative to corresponding brain-accumulated enhancement (r = 0.75; r = 0.72). Conclusion (18F)FDOPA PET resulted in substantial larger tumor volumes compared to MRI; however, its added value is unclear as vast majority of recurrences occurred within the prescribed dose level. Use of PET/CT signals proved to be feasible in the absence of direct segmentation possibilities of PET/MR in TPS. The added value of (18F)FDOPA may be better exploited in the context of integrated dose escalation.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Frontiers in Oncology. - 11 (2021), p. 1-11. -
További szerzők:László Zoltán (1979-) (biokémikus, molekuláris biológus) Tóth Zoltán Kovács Péter Tollár József Gulybán Ákos (Pécs) Lakosi Ferenc Repa Imre (1950-) (radiológus) Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus)
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Intézményi repozitóriumban (DEA) tárolt változat
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5.

001-es BibID:BIBFORM088768
Első szerző:Sipos Dávid
Cím:Possible predictors of burnout among radiographers in Hungary : demographic and work related characteristics / David Sipos, Omar Freihat, Attila András Pandur, József Tollár, András Kedves, Imre Repa, Árpád Kovács, Melinda Petőné Csima
Dátum:2020
ISSN:1212-4117 1804-7122
Megjegyzések:Introduction: The risk of burnout in healthcare can affect the quality of patient care. The purpose of this study was to assess burnout rates among Hungarian radiographers to find out the possible reasons behind the phenomenon. Methods: Quantitative, cross-sectional, descriptive data collection was conducted from June to September 2018. In addition to socio-demographic and work-related characteristics, an internationally validated Maslach Burnout Inventory (MBI) was used. Descriptive statistics, one-sample t-test, ANOVA, Mann-Whitney and Kruskal-Wallis test with 95% probability were used for statistical items (p = 0.05). Results: We examined 238 radiographers' data with the mean age of 34.42 years (SD 10.53). Woman respondents dominated the sample but male respondents tend to be more affected by burnout (p = 0.001). Working over 50 hours per week affected negatively the dimensions of depersonalization and emotional exhaustion. 40 to 50 hours of work per week affected foremost the personal achievement dimension (p = 0.001). Radiographers working in oncology patient care are more affected by emotional exhaustion (p = 0.001). Respondents who rated their health as excellent had higher values of personal achievement (p = 0.01). They also had significantly lower levels of emotional exhaustion than respondents who considered their health status to be tolerable or poor (p = 0.001). Conclusions: The extent of burnout may vary depending on the radiographers' work related characteristics. Understanding the risk factors associated with burnout may help us develop strategies for prevention.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Burnout
Healthcare
Maslach Burnout Inventory
Radiographer
Megjelenés:Kontakt. - 22 : 4 (2020), p. 228-234. -
További szerzők:Freihat, Omar Pandur Attila András Tollár József Kedves András Repa Imre (1950-) (radiológus) Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus) Petőné Csima Melinda
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Intézményi repozitóriumban (DEA) tárolt változat
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6.

001-es BibID:BIBFORM087668
035-os BibID:(WoS)000613505800002 (Scopus)85091897870
Első szerző:Tollár József
Cím:High frequency and intensity rehabilitation in 641 subacute ischemic stroke patients / Tollár József, Ferenc Nagy, Bence Csutorás, Nándor Prontvai, Zsófia Nagy, Katalin Török, Eszter Blényesi, Zsolt Vajda, Dóra Farkas, Béla E. Tóth, Imre Repa, Mariann Moizs, Dávid Sipos, András Kedves, Árpád Kovács, Tibor Hortobágyi
Dátum:2021
ISSN:0003-9993
Megjegyzések:Objective To determine the effects of Exergaming on quality of life (QoL), motor, and clinical symptoms in sub-acute stroke patients. Design A pseudo randomized clinical trial, using a before-after test design. Settings University hospital setting. Participants Of 3,857 sub-acute, ischemic stroke outpatients, 680 were randomized and 641 completed the study. Interventions We determined the effects of 5x/week twice (EX2, 50 sessions, n=286) and once daily (EX1, 25 sessions, n=272) Exergaming and low-intensity standard care (CON, 25 sessions, n=83) on clinical, mobility, blood pressure (BP), and QoL outcomes. Main Outcome Measures The primary outcome: Modified Rankin Scale (mRS). Secondary outcomes: Activities of daily living (ADL), five aspects of health-related QoL(EQ-5D), Beck Depression Inventory (BDI), six-minute walk test (6MWT), Berg Balance Scale (BBS) and static balance (center of pressure, COP). Results During exercise, peak heart rate was 134, 134, and 126 b?min-1 in EX2, EX1, and CON. mRS improved similarly in EX2 (-1.8, effect size, d=-4.0) and EX1 (-1.4, d=-2.6) but more than in CON (-0.7, d=-0.6). QoL, Barthel index, Berg balance scale, six-minute walk test, and standing posturography improved in a pattern of EX2>EX1=CON. Systolic and diastolic rBP decreased more in EX2 and EX1 than CON. The intervention effects did no differ between males (n=349) and females (n=292). Conclusion Twice daily compared with once daily high-intensity Exergaming or once-daily lower intensity standard care produced superior effects on clinical and motor symptoms, BP, and QoL in male and female sub-acute ischemic stroke participants.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Virtual reality
Exercise
Quality of life
Activities of daily living
Gender
Megjelenés:Archives Of Physical Medicine And Rehabilitation. - 102 : 1 (2021), p. 9-18. -
További szerzők:Nagy Ferenc (neurológus Kaposvár) Csutorás Bence Prontvai Nándor Nagy Zsófia Török Katalin Blényesi Eszter Vajda Zsolt Farkas Dóra (1968-) (gyógytornász) Tóth E. Béla (1960-) (orvos) Repa Imre (1950-) (radiológus) Moizs Marianna (1964-) (orvos) Sipos Dávid Kedves András Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus) Hortobágyi Tibor
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Intézményi repozitóriumban (DEA) tárolt változat
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