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001-es BibID:	BIBFORM103703
035-os BibID:	(cikkazonosító)2131 (Scopus)85130241509 (WoS)000803398400001
Első szerző:	Nagy Rita
Cím:	In-Hospital Patient Education Markedly Reduces Alcohol Consumption after Alcohol-Induced Acute Pancreatitis / Nagy Rita, Ocskay Klementina, Váradi Alex, Papp Mária, Vitális Zsuzsanna, Izbéki Ferenc, Boros Eszter, Gajdán László, Szentesi Andrea, Erőss Bálint, Hegyi Péter Jenő, Vincze Áron, Bajor Judit, Sarlos Patricia, Mikó Alexandra, Márta Katalin, Pécsi Dániel, Párniczky Andrea, Hegyi Péter
Dátum:	2022
ISSN:	2072-6643
Megjegyzések:	Although excessive alcohol consumption is by far the most frequent cause of recurrent acute pancreatitis (AP) cases, specific therapy is still not well established to prevent recurrence. Generally, psychological therapy (e.g., brief intervention (BI)) is the cornerstone of cessation programs; however, it is not yet widely used in everyday practice. We conducted a post-hoc analysis of a prospectively collected database. Patients suffering from alcohol-induced AP between 2016 and 2021 received 30 min BI by a physician. Patient-reported alcohol consumption, serum gamma-glutamyl-transferase (GGT) level, and mean corpuscular volume (MCV) of red blood cells were collected on admission and at the 1-month follow-up visit to monitor patients' drinking habits. Ninety-nine patients with alcohol-induced AP were enrolled in the study (mean age: 50 ? 11, 89% male). A significant decrease was detected both in mean GGT value (294 ? 251 U/L vs. 103 ? 113 U/L, p < 0.001) and in MCV level (93.7 ? 5.3 U/L vs. 92.1 ? 5.1 U/L, p < 0.001) in patients with elevated on-admission GGT levels. Notably, 79% of the patients (78/99) reported alcohol abstinence at the 1-month control visit. Brief intervention is an effective tool to reduce alcohol consumption and to prevent recurrent AP. Longitudinal randomized clinical studies are needed to identify the adequate structure and frequency of BIs in alcohol-induced AP
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Nutrients. - 14 : 10 (2022), p. 1-9. -
További szerzők:	Ocskay Klementina Váradi Alex (1991-) (biológus) Papp Mária (1975-) (belgyógyász, gasztroenterológus) Vitális Zsuzsanna (1963-) (belgyógyász, gasztroenterológus) Izbéki Ferenc Boros Eszter Gajdán László Szentesi Andrea Erőss Bálint Hegyi Péter Jenő (belgyógyász) Vincze Áron Bajor Judit Sarlós Patrícia Mikó Alexandra Márta Katalin Pécsi Dániel Párniczky Andrea (gyermekgyógyász) Hegyi Péter (pszichológus)
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001-es BibID:	BIBFORM094178
035-os BibID:	(WOS)000727779500019 (Scopus)85106978919
Első szerző:	Szakó Lajos
Cím:	Early occurrence of pseudocysts in acute pancreatitis - A multicenter international cohort analysis of 2275 cases / Lajos Szakó, Noémi Gede, Alex Váradi, Benedek Tinusz, Nóra Vörhendi, Dóra Mosztbacher, Áron Vincze, Tamás Takács, László Czakó, Ferenc Izbéki, László Gajdán, Veronika Dunás-Varga, József Hamvas, Mária Papp, Krisztina Eszter Fehér, Márta Varga, Artautas Mickevicius, Imola Török, Klementina Ocskay, Márk Félix Juhász, Szilárd Váncsa, Nándor Faluhelyi, Orsolya Farkas, Attila Miseta, András Vereczkei, Alexandra Mikó, Péter Jenő Hegyi, Andrea Szentesi, Andrea Párniczky, Bálint Erőss, Péter Hegyi
Dátum:	2021
ISSN:	1424-3903
Megjegyzések:	BACKGROUND Pseudocysts being the most frequent local complications of acute pancreatitis (AP) have substantial effect on the disease course, hospitalization and quality of life of the patient. Our study aimed to understand the effects of pre existing (OLD-P) and newly developed (NEW-P) pseudocysts on AP. METHODS Data were extracted from the Acute Pancreatitis Registry organized by the Hungarian Pancreatic Study Group (HPSG). 2275 of 2461 patients had uploaded information concerning pancreatic morphology assessed by imaging technique. Patients were divided into "no pseudocyst" (NO-P) group, "old pseudocyst" (OLD-P) group, or "newly developed pseudocyst" (NEW-P) groups. RESULTS The median time of new pseudocyst development was nine days from hospital admission and eleven days from the beginning of the abdominal pain. More NEW-P cases were severe (15.9% vs 4.7% in the NO-P group p<0.001), with longer length of hospitalization (LoH) (median: 14 days versus 8 days, p<0.001), and were associated with several changed laboratory parameters. OLD-P was associated with male gender (72.2% vs. 56.1%, p=0.0014), alcoholic etiology (35.2% vs. 19.8% in the NO-P group), longer hospitalization (median: 10 days, p<0.001), a previous episode of AP (p<0.001), pre-existing diagnosis of chronic pancreatitis (CP) (p<0.001), current smoking (p<0.001), and increased alcohol consumption (unit/week) (p=0.014). CONCLUSION Most of the new pseudocysts develop within two weeks. Newly developing pseudocysts are associated with a more severe disease course and increased length of hospitalization. Pre-existing pseudocysts are associated with higher alcohol consumption and smoking. Because CP is more frequently associated with a pre-existing pseudocyst, these patients need closer attention after AP.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Pancreatology. - 21 : 6 (2021), p. 1161-1172. -
További szerzők:	Gede Noémi Váradi Alex (1991-) (biológus) Tinusz Benedek Vörhendi Nóra Mosztbacher Dóra Vincze Áron Takács Tamás (Szeged) Czakó László Izbéki Ferenc Gajdán László Dunás-Varga Veronika Hamvas József Papp Mária (1975-) (belgyógyász, gasztroenterológus) Fehér Krisztina Eszter Varga Márta Mickevicius, Artautas Török Imola Ocskay Klementina Juhász Márk Félix Váncsa Szilárd Faluhelyi Nándor Farkas Orsolya Miseta Attila Vereczkei András Mikó Alexandra Hegyi Péter Jr. (belgyógyász) Szentesi Andrea Párniczky Andrea (gyermekgyógyász) Erőss Bálint Hegyi Péter Jenő (belgyógyász)
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001-es BibID:	BIBFORM113553
035-os BibID:	(scopus)85153309480 (wos)000973548200001
Első szerző:	Váncsa Szilárd
Cím:	Metabolic-associated fatty liver disease is associated with acute pancreatitis with more severe course : Post hoc analysis of a prospectively collected international registry / Váncsa Szilárd, Sipos Zoltán, Váradi Alex, Nagy Rita, Ocskay Klementina, Juhász Félix Márk, Márta Katalin, Teutsch Brigitta, Mikó Alexandra, Hegyi Péter Jenő, Vincze Áron, Izbéki Ferenc, Czakó László, Papp Mária, Hamvas József, Varga Márta, Török Imola, Mickevicius Artautas, Erőss Bálint, Párniczky Andrea, Szentesi Andrea, Pár Gabriella, Hegyi Péter, Hungarian Pancreatic Study Group
Dátum:	2023
ISSN:	2050-6406 2050-6414
Megjegyzések:	Introduction - Non?alcoholic fatty liver disease (NAFLD) is a proven risk factor for acute pancreatitis (AP). However, NAFLD has recently been redefined as metabolic?associated fatty liver disease (MAFLD). In this post hoc analysis, we quantified the effect of MAFLD on the outcomes of AP. Methods - We identified our patients from the multicentric, prospective International Acute Pancreatitis Registry of the Hungarian Pancreatic Study Group. Next, we compared AP patients with and without MAFLD and the individual components of MAFLD regarding in?hospital mortality and AP severity based on the revised Atlanta classification. Lastly, we calculated odds ratios (ORs) with 95% confidence intervals (CIs) using multivariate logistic regression analysis. Results - MAFLD had a high prevalence in AP, 39% (801/2053). MAFLD increased the odds of moderate?to?severe AP (OR = 1.43, CI: 1.09?1.89). However, the odds of in?hospital mortality (OR = 0.89, CI: 0.42?1.89) and severe AP (OR = 1.70, CI: 0.97?3.01) were not higher in the MAFLD group. Out of the three diagnostic criteria of MAFLD, the highest odds of severe AP was in the group based on metabolic risk abnormalities (OR = 2.68, CI: 1.39?5.09). In addition, the presence of one, two, and three diagnostic criteria dose?dependently increased the odds of moderate?to?severe AP (OR = 1.23, CI: 0.88?1.70, OR = 1.38, CI: 0.93?2.04, and OR = 3.04, CI: 1.63?5.70, respectively) and severe AP (OR = 1.13, CI: 0.54?2.27, OR = 2.08, CI: 0.97?4.35, and OR = 4.76, CI: 1.50?15.4, respectively). Furthermore, in patients with alcohol abuse and aged ?60 years, the effect of MAFLD became insignificant. Conclusions - MAFLD is associated with AP severity, which varies based on the components of its diagnostic criteria. Furthermore, MAFLD shows a dose? dependent effect on the outcomes of AP.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	United European Gastroenterology Journal. - 11 : 4 (2023), p. 371-382. -
További szerzők:	Sipos Zoltán (1988-) (vegyész, angol-magyar szakfordító) Váradi Alex (1991-) (biológus) Nagy Rita Ocskay Klementina Juhász Márk Félix Márta Katalin Teutsch Brigitta Mikó Alexandra Hegyi Péter Jenő (belgyógyász) Vincze Áron Izbéki Ferenc Czakó László Papp Mária (1975-) (belgyógyász, gasztroenterológus) Hamvas József Varga Márta Török Imola Mickevicius, Artautas Erőss Bálint Párniczky Andrea (gyermekgyógyász) Szentesi Andrea Pár Gabriella Hegyi Péter (pszichológus) Hungarian Pancreatic Study Group
Pályázati támogatás:	ÚNKP?22?3?II Egyéb ÚNKP?22?3?I Egyéb ÚNKP?22?5 Egyéb ÚNKP?22?4?II Egyéb FK131864 Egyéb
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