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001-es BibID:BIBFORM113910
035-os BibID:(cikkazonosító)e0011213 (scopus)85166363227 (wos)001031483300004
Első szerző:Akinsolu, Folahanmi Tomiwa
Cím:Community perception of school-based mass drug administration program for soil-transmitted helminths and Schistosomiasis in Ogun State, Nigeria / Akinsolu Folahanmi T., Abodunrin Olunike R., Olagunju Mobolaji T., Adewole Ifeoluwa E., Rahman Nurudeen O., Dabar Anita M., Njuguna Diana W., Soneye Islamiat Y., Salako Abideen O., Ezechi Oliver C., Varga Orsolya E., Akinwale Olaoluwa P.
Dátum:2023
ISSN:1935-2735
Megjegyzések:BACKGROUND: Neglected tropical diseases, such as soil-transmitted helminths and Schistosomiasis, are prevalent in sub-Saharan Africa, particularly Ogun State, Nigeria. School-based mass drug administration program is the primary control intervention, but the coverage and uptake of this intervention have been inadequate. This study aimed to investigate community perceptions of school-based mass drug administration programs for these infections in Ogun State, Nigeria, and identify the barriers to their uptake and coverage. METHODOLOGY/PRINCIPAL FINDINGS: The study used a qualitative research approach involving focus group discussions and in-depth interviews with community members and stakeholders engaged in neglected tropical disease control programs in Ogun State, Nigeria. A semi-structured questionnaire guided the exploration of ideas, and the data were analyzed using the QRS Nvivo 12 software package. The study found several barriers, such as the influence of parents, lack of sufficient knowledge, and side effects. The study recommended strategies such as improving community sensitization and engagement, drug distribution and performance, and enhancing partner collaboration and coordination to improve the school-based mass drug administration programs. CONCLUSIONS/SIGNIFICANCE: The study revealed correct perceptions of transmission but some misconceptions about disease causation, transmission, and drug safety. Participants expressed a desire for better sensitization campaigns and more assurances of their safety. The study recommends strengthening health education messages and increasing the visibility of on-site medical personnel. The findings have implications for improving the performance of these programs and reducing the burden of intestinal parasitic infections in the community. The study highlights the need for community engagement and education, health system support, and partner collaboration to successfully implement mass drug administration programs. Copyright: ? 2023 Akinsolu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:PLOS Neglected Tropical Diseases. - 17 : 7 (2023), p. 1-19. -
További szerzők:Abodunrin, Olunike R. Olagunju, Mobolaji T. Adewole, Ifeoluwa E. Rahman, Nurudeen O. Dabar Anita M. Njuguna, Diana Wangeshi (1983-) Soneye, Islamiat Y. Salako, Abideen O. Ezechi, Oliver C. Varga Orsolya (1977-) (orvos, jogász) Akinwale, Olaoluwa P.
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2.

001-es BibID:BIBFORM079736
035-os BibID:(cikkazonosító)1925 (PMID)31151318 (Scopus)85066955929 (WOS)000472132900053
Első szerző:Akinsolu, Folahanmi Tomiwa
Cím:Emerging resistance of neglected tropical diseases : a scoping review of the literature / Folahanmi T. Akinsolu, Priscilla O. Nemieboka, Diana W. Njuguna, Makafui N. Ahadji, Dora Dezso, Orsolya Varga
Dátum:2019
ISSN:1661-7827 1660-4601
Megjegyzések:Background: Antimicrobial resistance (AMR) is a global public health threat with the potential to cause millions of deaths. There has been a tremendous increase in the use of antimicrobials, stemming from preventive chemotherapy elimination and control programs addressing neglected tropical diseases (NTDs). This study aims to identify the frequency of drug resistance for 11 major NTDs and 20 treatment drugs within a specific period by systematically analyzing the study design, socio-demographic factors, resistance, and countries of relevant studies. Methods: Adhering to PRISMA guidelines, we performed systematic reviews of the major 11 NTDs to identify publications on drug resistance between 2000 and 2016. A quality assessment tool adapted for evaluating observational and experimental studies was applied to assess the quality of eligible studies. Results: One of the major findings is that six NTDs have information on drug resistance, namely human African trypanosomiasis, leishmaniasis, onchocerciasis, schistosomiasis, soil-transmitted helminths, and trachoma. Many studies recorded resistance due to diagnostic tests, and few studies indicated clinical resistance. Although most studies were performed in Africa where there is the occurrence of several NTDs, there was no link between disease burden and locations of study. Conclusions: Based on this study we deduce that monitoring and surveillance systems need to be strengthened to enable the early detection of AMR and the mitigation of its global spread.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
antimicrobial resistance
drug resistance
monitoring
neglected tropical diseases
surveillance
Megjelenés:International Journal of Environmental Research and Public Health. - 16 : 11 (2019), p. 1-14. -
További szerzők:Nemieboka, Priscilla O. Njuguna, Diana Wangeshi (1983-) Ahadji, Makafui N. Kölesné Dezső Dóra (1985-) (orvos) Varga Orsolya (1977-) (orvos, jogász)
Pályázati támogatás:FOP-3.6.3-VEKOP-16-2017-00009
EFOP
ÚNKP-18-4-DE-71
egyéb
TÉT_16-1-2016-0093
egyéb
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3.

001-es BibID:BIBFORM076240
Első szerző:Akinsolu, Folahanmi Tomiwa
Cím:Developing a database for Rett syndrome research performed in the European Union : a resource for researchers and stakeholders / Folahanmi Tomiwa Akinsolu, Eszter Balczár, Nóra Kovács, Tibor Gáll, Mariann Harangi, Orsolya Varga
Dátum:2018
ISSN:0305-1862
Megjegyzések:Background For most rare diseases, which are often significantly under?resourced, sufficient information on funding landscape is missing, which may prevent effective use of research resources and be an obstacle to making effective decisions on research. The objective of this research was to create a database of Rett syndrome research projects carried out in the European Union (EU) and to provide a research landscape analysis. Method Websites of organizations funding research projects were identified and systematically checked. Projects were analysed by date, place, funder types, and research topics. Results The analysis revealed that the total expenditure on Rett syndrome research was almost ?70 million, allocated among 247 projects mostly performed in Italy and the United Kingdom. The main research sponsor was the European Commission. Highlighting research trends and gaps, this work facilitates changes in rare disease research data management. Conclusion This work demonstrates the feasibility of creating an EU?based research database on Rett syndrome projects. It provides a source of information on research development which is useful for individuals, organizations and key players in the private and public sector to make progressive decisions on Rett syndrome research.
Tárgyszavak:Természettudományok Biológiai tudományok kutatási jelentés
Megjelenés:Child Care Health And Development. - 44 : 5 (2018), p. 794-800. -
További szerzők:Balczár Eszter Kovács Nóra (1989-) (népegészségügyi szakember) Gáll Tibor (1969-) (egészségügyi menedzser) Harangi Mariann (1974-) (belgyógyász, endokrinológus) Varga Orsolya (1977-) (orvos, jogász)
Pályázati támogatás:TÁMOP 4.2.4.A/2?11/1?2012?0001
TÁMOP
TÁMOP 4.2.2.A?11/1/KONV?2012?0031
TÁMOP
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4.

001-es BibID:BIBFORM071054
Első szerző:Akinsolu, Folahanmi Tomiwa
Cím:Patent Landscape of Neglected Tropical Diseases: An analysis of worldwide patent families / Folahanmi Tomiwa Akinsolu, Vitor Nobre de Paiva, Samuel Santos Souza, Varga Orsolya
Dátum:2017
ISSN:1744-8603
Megjegyzések:Background: "Neglected Tropical Diseases" (NTDs) affect millions of people in Africa, Asia and South America. The two primary ways of strategic interventions are "preventive chemotherapy and transmission control" (PCT), and "innovative and intensified disease management" (IDM). In the last five years, phenomenal progress has been achieved. However, it is crucial to intensify research effort into NTDs, because of the emerging drug resistance. According to the World Health Organization (WHO), the term NTDs covers seventeen diseases, namely buruli ulcer, Chagas disease, dengue, dracunculiasis, echinococcosis, trematodiasis, human African trypanosomiasis, leishmaniasis, leprosy, lymphatic filariasis, onchocerciasis, rabies, schistosomiasis, soil-transmitted helminthes, taeniasis, trachoma, and yaws. The aim of this study is to map out research and development (R&D) landscape through patent analysis of these identified NTDs. To achieve this, analysis and evaluation have been conducted on patenting trends, current legal status of patent families, priority countries by earliest priority years and their assignee types, technological fields of patent families over time, and original and current patent assignees.Main body: Patent families were extracted from Patseer, an international database of patents from over 100 patent issuing authorities worldwide. Evaluation of the patents was carried out using the combination of different search terms related to each identified NTD. In this paper, a total number of 12,350 patent families were analyzed. The main countries with sources of inventions were identified to be the United States (US) and China. The main technological fields covered by NTDs patent landscape are pharmaceuticals, biotechnology, organic fine chemistry, analysis of biological materials, basic materials chemistry, and medical technology. Governmental institutions and universities are the primary original assignees. Among the NTDs, leishmaniasis, dengue, and rabies received the highest number of patent families, while human African trypanosomiasis (sleeping sickness), taeniasis, and dracunciliasis received the least. The overall trend of patent families shows an increase between 1985 and 2008, and followed by at least 6 years of stagnation. Conclusion: The filing pattern of patent families analyzed undoubtedly reveals slow progress on research and development of NTDs. Involving new players, such as non-governmental organizations may help to mitigate and reduce the burden of NTDs.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Neglected Tropical Diseases
patents
preventive chemotherapy
intensified disease management
mass drug administration
Megjelenés:Globalization and Health. - 13 : 82 (2017), p. 1-13. -
További szerzők:De Paiva, Vitor Nobre Souza, Samuel Santos Varga Orsolya (1977-) (orvos, jogász)
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5.

001-es BibID:BIBFORM087406
Első szerző:Franco, Nuno Henrique
Cím:Trends in animal model preference for preclinical drug testing for type-2 diabetes and future directions / Nuno Henrique Franco, Sónia Batista Miranda, Nora Kovacs, Attila Nagy, Folahanmi Tomiwa Akinsolu, I. Anna S. Olsson, Orsolya Varga
Dátum:2020
Tárgyszavak:Orvostudományok Gyógyszerészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:bioRxiv. - 2020 (2020), p. 1-6. -
További szerzők:Sónia, Batista Miranda Kovács Nóra (1989-) (népegészségügyi szakember) Nagy Attila Csaba (1981-) (megelőző orvostan és népegészségtan szakorvos, epidemiológus) Akinsolu, Folahanmi Tomiwa (1987-) Olsson, I. Anna Varga Orsolya (1977-) (orvos, jogász)
Pályázati támogatás:TÉT_16-1-2016-0093
Egyéb
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