CCL

Összesen 4 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM073024
035-os BibID:(WoS)000366646400029 (Scopus)84951907147
Első szerző:Tóth Dezső (sebész, onkológus)
Cím:Predictive Factors for Positive Margin and the Surgical Learning Curve in Non-Palpable Breast Cancer After Wire-Guided Localization - Prospective Study of 214 Consecutive Patients / Dezső Tóth, Zsolt Varga, Éva Sebő, Miklós Török, Ilona Kovács
Dátum:2016
ISSN:1219-4956 1532-2807
Megjegyzések:To investigate the most commonly used technique, the wire-guided localization (WGL) in non-palpable breast cancer. To analyze the effective factors on positive surgical margins in our practice and determine the surgical learning curve of this method. Prospective consecutive study was performed from January 2005 to December 2011. Inclusion criteria was a non-palpable breast lesion with malignancy on preoperative histology. All lesions were localized by ultrasound or stereotactic guided wire placement. Margins 1 mm or closer were accepted as positive margins which required re-excision. To determine the learning curve of WGL method we investigated the change in the reoperation rate after primary procedure performed by "high-volume" surgeon. Two hundred and fourteen consecutive patients were enrolled. In 23 patients (10.7%) reexcision was needed. Positive surgical margins were significantly influenced by the patient's age (p?=?0.03), tumor volume (p?<?=0.001), proportion of tumor volume/specimen volume (p?<?0.001), presence of DCIS (p?<?0.001), multifocality (p?=?0.03) and the learning curve (p?=?0.006) with univariate analysis. Only the tumor volume, presence of DCIS and the learning curve were proved as independent prognostic factor for reoperation by multivariate analysis. The reoperation rate decreased below 20% after the fortieth operation. Results of our single institutional study suggest, that this localization technique can be performed safely with very good results after 40 procedures as a learning curve for surgeons.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Breast cancer
Learning curve
Non-palpable
Surgery
Wire-guided localization
Megjelenés:Pathology & Oncology Research. - 22 : 1 (2016), p. 209-215. -
További szerzők:Varga Zsolt József (1987-) (orvos) Sebő Éva Török Miklós (1976-) (pathológus) Kovács Ilona (1965-) (patológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM070321
Első szerző:Tóth Dezső (sebész, onkológus)
Cím:Comparison of different lymph node staging systems in prognosis of gastric cancer : a bi-institutional study from Hungary / Dezső Tóth, Adrienn Bíró, Zsolt Varga, Miklós Török, Péter Árkosy
Dátum:2017
ISSN:1000-9604
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Chinese Journal of Cancer Research. - 29 : 4 (2017), p. 323-332. -
További szerzők:Biró Adrienn (1988-) (orvos) Varga Zsolt József (1987-) (orvos) Török Miklós (1976-) (pathológus) Árkosy Péter (1962-) (általános sebész, mellkassebész)
Internet cím:DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

3.

001-es BibID:BIBFORM112933
035-os BibID:(cikkazonosító)1611270 (WoS)001028006400001 (Scopus)85164849700
Első szerző:Varga Zsolt József (orvos)
Cím:A combined approach for individualized lymphadenectomy in gastric cancer patients / Zsolt Varga, Adrienn Biró, Miklós Török, Dezső Tóth
Dátum:2023
ISSN:1219-4956 1532-2807
Megjegyzések:Introduction: Gastric cancer ranks as the fifth most common cancer globally. The presence of lymph node metastasis is a significant prognostic factor influencing survival. Postoperative morbidity and nodal staging accuracy are heavily affected by the extent of lymph node dissection. Our study aimed to explore the potential integration of two contemporary methods, sentinel node navigation surgery (SNNS) and the Maruyama Computer Program (MCP), to improve the accuracy of nodal staging. Materials and methods: We conducted a prospective data collection involving patients with gastric adenocarcinoma from 2008 to 2018 at the Department of Surgery, University of Debrecen, Hungary. Data from 100 consecutive patients were collected. The primary and secondary endpoints included evaluating the rate of node-negative patients and the diagnostic accuracy of our combined approach. Results: Sentinel node mapping was successful in 97 out of 100 patients. We found that using the threshold value of the Maruyama Index (MI) ? 28, all metastatic stations of sentinel-node-negative patients could be identified. Our method achieved 100% sensitivity and negative predictive value, with a specificity of 60.42% (95% CI = 46.31%?72.98%). Discussion: The combined application of SNNS and MCP has proven to be an effective diagnostic technique in the synergistic approach for identifying metastasis-positive lymph node stations. Despite its limitations, this combination may assist clinicians in customizing lymphadenectomy for gastric cancer patients.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
gyomorrák
sebészet
limfadenektómia
sentinel
Maruyama
Megjelenés:Pathology & Oncology Research. - 29 (2023), p. 1-10. -
További szerzők:Biró Adrienn (1988-) (orvos) Török Miklós (1976-) (pathológus) Tóth Dezső (1972-) (sebész, onkológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

4.

001-es BibID:BIBFORM073046
Első szerző:Varga Zsolt József (orvos)
Cím:Breast Cancer in Surgical Site : unusual Presentation of an Ectopic Milk Line Malignancy / Zsolt Varga, Miklós Török, Éva Sebő, Judit Tóth, Dezső Tóth
Dátum:2016
Megjegyzések:Primary ectopic breast cancer is a rare entity, which is mistaken for other benign skin or soft tissue lesions, easily.A 56-year old woman with history of laparoscopic cholecystectomy was referred to outpatient clinic 3 years after the operation with a non- healing reddish lump in the surgical scar. The lesion was situated at the site of the right subcostal port, in the medioclavicular line, below the ribcage. Local excision was performed and histological evaluation revealed poorly differentiated adenocarcinoma, which was thought to be metastatic. After multiple recurrences, appearance of an axillary lymph node metastasis and persistent search without any sign of other tumor, it had to be considered as a possibility, if there is no distant source of metastases, rather than a the lesion is a primary cancer. Relying on its location, behavior and result of immunohistochemistry, multidisciplinary team identi ed the lesion as triple-negative ectopic breast cancer. We performed a radical excision extended to the peritoneum, including partial, 3 cm long resection of the eleventh rib and a level II. Right-sided axillary block dissection was done simultaneously. The abdominal wall was reconstructed with component separation technique combining polypropylene and polytetra uoroethylene meshes. The multidisciplinary team proposed a treatment for triple- negative ectopic milk-line breast cancer, containing 4 cycles of TAC chemotherapy and fractionated 50 Gray dose of local radiotherapy. This adjuvant oncological treatment is in progress.This entity should be considered in differential diagnosis in cases of adenocarcinomas close to normal breasts and in the line of embryonic mammary ridges. So, we can avoid a signi cant delay in treatment and we can offer a better prognosis for the patient.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Breast cancer
Ectopic breast
Aberrant breast tissue
Milk line
Surgery
Megjelenés:International Journal of Cancer and Clinical Research. - 3 : 1 (2016), p. 1-3. -
További szerzők:Török Miklós (1976-) (pathológus) Sebő Éva Tóth Judit Tóth Dezső (1972-) (sebész, onkológus)
Internet cím:Szerző által megadott URL
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Rekordok letöltése1