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001-es BibID:	BIBFORM109257
035-os BibID:	(Scopus)85149477136 (WoS)000942239000001
Első szerző:	Csernus Brigitta (élelmiszerbiztonsági és -minőségi mérnök)
Cím:	Capsanthin supplementation modulates the immune response in broiler chickens under Escherichia coli lipopolysaccharide challenge / Brigitta Csernus, Csaba Szabó, Renáta Knop, Reda Gebrehaweria Kidane, Sawadi Fransisco Ndunguru, Gabriella Gulyás, Xénia Erika Ozsváth, Levente Czeglédi
Dátum:	2023
ISSN:	2363-9822
Megjegyzések:	Due to the legislation of antibiotic usage, natural substances are required for application in the poultry industry. Because of their potential anti-inflammatory and immunomodulatory effects, carotenoids are great sources. Capsanthin, a major carotenoid giving the red color of pepper, is a promising feed additive, as it can reduce chronic inflammation. This study was conducted to determine the effects of capsanthin supplementation at 80 mg kg?1 in feed on the immune response of broiler chickens under Escherichia coli O55:B5 lipopolysaccharide (LPS) challenge. Ross 308 male broilers were divided into treatments: control (basal diet) and feedsupplemented groups. At 42 d of age, chickens were weighed and then challenged with 1 mg LPS per kilogram of body weight intraperitoneally. Four hours after injection, birds were euthanized, and then spleen and blood samples were collected. Capsanthin supplement at 80 mg kg?1 did not change the growth parameters and the relative spleen weight. LPS immunization resulted in higher splenic interleukin-1? (IL-1?), interleukin-6 (IL-6), and interferon-? (IFN-? ) mRNA expressions. Capsanthin addition reached lower gene expression levels of IL-6 and IFN-? compared to the LPS-injected birds. At plasma level, dietary capsanthin resulted in lower IL-1? and IL-6 levels. These results may indicate the potential anti-inflammatory effect of capsanthin supplementation in broiler chickens.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk capsanthin broiler chicken gene expression immunology
Megjelenés:	Archives Animal Breeding. - 66 : 1 (2023), p. 103-111. -
További szerzők:	Szabó Csaba (1968-) (agrármérnök) Knop Renáta (1983-) (állatorvos) Reda, Gebrehaweria Kidane (Phd hallgató) Ndunguru, Sawadi Fransisco (1980-) Gulyás Gabriella (1985-) (agrár) Ozsváth Xénia Erika Czeglédi Levente (1977-) (agrármérnök)
Pályázati támogatás:	TKP2020-NKA-04 Egyéb ÚNKP20-4-I-DE-101 Egyéb K139021 OTKA
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM089659
035-os BibID:	(Scopus)85091883948
Első szerző:	Csernus Brigitta (élelmiszerbiztonsági és -minőségi mérnök)
Cím:	Physiological, antimicrobial, intestine morphological, and immunological effects of fructooligosaccharides in pigs / Csernus Brigitta, Czeglédi Levente
Dátum:	2020
ISSN:	2363-9822
Megjegyzések:	In pig nutrition, there are some periods when natural alternatives to antibiotics are more required, such as during suckling and weaning. Fructooligosaccharides (FOSs) are a group of prebiotics applied as feed ingredients in animal nutrition since their positive effects on growth performance, immunological parameters, intestinal microbiota, and gut morphology are reported. Accordingly, FOS may be candidate molecules to improve the mentioned properties in pigs. Previous studies defined FOS as inhibiting the activity of pathogens and increasing the colonization of beneficial bacteria in the gut, although metabolites of FOS decreased the intestinal pH value. Beneficial effects on digestive-enzyme activities and on protein digestion were determined in some studies. All of the three types of FOS (inulin, oligomeric fructans, and short-chain FOSs) promoted the microbial composition of the gut by increasing the colonizations of Lactobacillus, Bifidobacterium, and Prevotella genus. FOS also affected the immune response directly and indirectly and increased vaccine-specific IgA, serum IgG, and IgE levels. Moreover, FOS enhanced the activation of T cells and altered the secretions of some cytokines. Levels of vaccine-specific IgG could not be increased after FOS supplements. In most cases, FOS modified intestinal morphological parameters, such as longer villi, villus-height-to-crypt-depth ratio, and thicker mucosa, which could suggest better absorptive functions. Results are contradictory on growth performance, which might be influenced by the chemical structure, the duration, and the dose of FOS, so further studies are required. This review aims to gather information regarding immunological, antimicrobial, intestine morphological, and growth performance properties of fructooligosaccharides in pigs.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Archives Animal Breeding. - 63 : 2 (2020), p. 325-335. -
További szerzők:	Czeglédi Levente (1977-) (agrármérnök)
Pályázati támogatás:	EFOP-3.6.3-VEKOP-16-2017-00008 EFOP GINOP-2.3.2-15-2016-00042 GINOP
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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