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001-es BibID:BIBFORM106086
035-os BibID:(cikkazonosító)1 (WOS)000908911400001 (Scopus)85145920793
Első szerző:Valido, Ezra
Cím:Systematic Review of Human and Animal Evidence on the Role of Buckwheat Consumption on Gastrointestinal Health / Valido Ezra, Stoyanov Jivko, Gorreja Frida, Stojic Stevan, Niehot Christa, Kiefte-de Jong Jessica, Llanaj Erand, Muka Taulant, Glisic Marija
Dátum:2023
ISSN:2072-6643
Megjegyzések:Background: Buckwheat is a commonly cultivated crop with growing evidence that it is beneficial to gastrointestinal (GI) health. This systematic review summarizes the role of buckwheat in modifying GI health outcomes and microbiomes. Methods: Four medical databases and Google Scholar were systematically searched. Clinical trials, observational studies, animal in vivo, and in vitro studies with human and animal GI-derived samples were included. Results: There were 32 studies (one randomized controlled trial [RCT], one non-randomized trial, 3 observational, 9 in vitro, and 18 animal in vivo studies) included. In preclinical studies, buckwheat extracts were observed to have cytotoxic potential against human-derived GI cancer cell lines. Animals fed with buckwheat had lower GI mucosal inflammation, higher alpha diversity in the GI microbiome, and higher levels of fecal short-chain fatty acids. Human evidence studies and clinical trials were limited and predominantly of moderate risk of bias. The majority of in vitro studies with GI-derived samples and in vivo studies were reliable without restrictions in study design. Conclusion: In vivo and in vitro studies show that buckwheat may have potential GI benefits due to its anti-oxidant and anti-inflammatory potential; however, human evidence remains limited, and its impact on health in humans remains to be elucidated in future trials.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
buckwheat
Tartary buckwheat
gastrointestinal symptoms
microbiome
Megjelenés:Nutrients. - 15 : 1 (2023), p. 1-18. -
További szerzők:Stoyanov, Jivko Gorreja, Frida Stojic, Stevan Niehot, Christa D. Kiefte-de Jong, Jessica Llanaj, Erand (1988-) (táplálkozási epidemiológus) Muka, Taulant Glisic, Marija
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