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001-es BibID:BIBFORM099845
035-os BibID:(cikkazonosító)745140 (WOS)000749873700001 (Scopus)85124040366
Első szerző:Papp Judit (onkoradiológus)
Cím:CBCT Verification of SRT for Patients With Brain Metastases / Papp Judit, Simon Mihály, Csiki Emese, Kovács Árpád
Dátum:2022
ISSN:2234-943X
Megjegyzések:Background: The aim of our work is to demonstrate the role of image guidance and volumetric imaging in stereotactic radiotherapy (SRT) of brain metastases. Methods: Between 2018 and 2020, 106 patients underwent intracranial stereotactic radiotherapy. 10 patients with metastatic brain tumors treated with SRT were randomly selected and included in our study model. Patients were scanned pre- and post-treatment with cone beam CT. Total of 100 verifications of 50 stereotaxic treatments were performed and analyzed. Results: Population mean X, Y, Z values were -0.13 cm, -0.04 cm, -0.03 cm, respectively, rotation values 0.81 degrees, 0.51 degrees, 0.46 degrees, respectively. Systematic error components for translational displacements pre corrections were as follows: 0.14 cm for X, 0.13 cm for Y and 0.1 cm for Z. Systematic error components of the post-treatment HR 3D CBCTs were as follows: 0.01 cm for X, 0.06 cm for Y and 0.04 cm for Z. Conclusions: Population mean values close to 0 confirmed that there is no systematic variation in our system and the accuracy of our equipment and tools is reliable. HR 3D CBCT scans performed pre SRTs further refine patient and target volume setting, support medical decision making and eliminate the possibility of gross error.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Frontiers in Oncology. - 11 (2022), p. 1-9. -
További szerzők:Simon Mihály (1981-) (Fizikus) Csiki Emese (1986-) (onkoradiológus) Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus)
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Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:BIBFORM100801
035-os BibID:(cikkazonosító)846609 (WOS)000776793600001 (Scopus)85127310676
Első szerző:Simon Mihály (Fizikus)
Cím:Plan Quality Assessment of Fractionated Stereotactic Radiotherapy Treatment Plans in Patients With Brain Metastases / Simon Mihály, Papp Judit, Csiki Emese, Kovács Árpád
Dátum:2022
ISSN:2234-943X
Megjegyzések:Background and Purpose: The treatment options available in the management of brain metastases includes fractionated stereotactic radiotherapy (FSRT) and stereotactic radiosurgery (SRS) treatments. FSRT treatments have proved to be useful mainly in the treatment of larger volumes. This study aims to evaluate the FSRT treatment technique used in our department based on various plan quality indices. Methods and Materials: 24 treatment plans of 23 patients were analyzed. Volumetric modulated arc therapy (VMAT) plans were generated in line with the department protocol. The following parameters were extracted: Radiation Therapy Oncology Group conformity index (RTOG CI), Paddick conformity index (Paddick CI), gradient index (GI), quality index (Q), homogeneity index (HI), and V24.4 volume as a parallel index of V12 used at SRS plan evaluation. Results: Plan conformity was acceptable, RTOG CI mean was 0.942; Paddick CI mean was 0.824. The mean GI value was 6.146. The mean of HI and Q indices were 1.263 and 0.94, respectively. V24.4 mean was 33.434 cm3 . All plans achieved clinically acceptable organs-at-risk (OAR) constraints. PTV volumes were clustered into either 10 cm3 or 15 cm3 bins depending on the plan quality metric we used. The mean values show a balanced distribution of plan indices along the various PTV bins. Discussion: Our results based on the derived indices show that our FSRT approach can achieve clinically acceptable treatment plans. Furthermore, the clustering of PTV volumes show that these plan quality metrics remain acceptable for a wide spectrum of PTV volumes. Keywords: FSRT = fractionated stereotactic radiotherapy, brain metastases, conformity index (CI), lina
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Frontiers in Oncology. - 12 (2022), p. 1-8. -
További szerzők:Papp Judit (1971-) (onkoradiológus) Csiki Emese (1986-) (onkoradiológus) Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
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