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001-es BibID:	BIBFORM117564
Első szerző:	Aroyeun, S. O.
Cím:	Effect of fermentation and storage on mycotoxigenic fungi, ochratoxin A and aflatoxin B1 in cocoa beans from Southwestern Nigeria / Aroyeun, S. O., Adegoke, G. O., Varga J., Kocsubé S., Pál K., Vágvölgyi Cs.
Dátum:	2007
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk cocoa beans detection mycotoxigenic fermentation Nigeria
Megjelenés:	Malaysian Cocoa Journal. - 3 (2007), p. 35-46. -
További szerzők:	Adegoke, G. O. Varga János Kocsubé Sándor Pál Károly (1978-) (mikrobiológus) Vágvölgyi Csaba
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001-es BibID:	BIBFORM117557
Első szerző:	Pál Károly (mikrobiológus)
Cím:	Sexual genes in the asexual filamentous fungus Aspergillus niger and related Aspergilli / Károly Pál, Anne D. van Diepeningen, János Varga, Alfons J. M. Debets, Rolf F. Hoekstra
Dátum:	2008
Megjegyzések:	Sexual reproduction is a general feature in higher eukaryotes, although the genetic machinery to produce sexually derived offspring can be very different. Contrary to the megabase-sized sexual chromosomes of animals, fungal genomes harbour much shorter sequences located at the MAT locus which governs the mating processes. For heterothallic fungi, the two mating-types are characterised by the presence of either of the two idiomorphs of the MAT locus, MAT-1 or MAT-2, while homothallic species may contain both MAT idiomorphs. The black mould Aspergillus niger is known as an asexual species, but some related presumed asexual species have recently been shown to have a cryptic sexual cycle. The scope of this work was to screen for and compare mating and meiosis related genes in the two sequenced A. niger genomes and to compare them to those in related Aspergilli. The MAT-1 mating type gene was found in both sequenced A. niger strains, a MAT-2 homologue was not detected in either, indicating that this species is either heterothallic or truly asexual. In comparison, the sequenced homothallic A. nidulans genome contains both MAT genes on different chromosomes, whereas the A. fumigatus, A. oryzae, and A. terreus genomes contain one MAT gene per sequenced genome. Many of the proteins known from Saccharomyces cerevisiae to be involved in meiosis proved well conserved in all five tested sexual and presumed asexual Aspergillus species. The Aspergilli also proved to have very similar sets of pheromone processing and response pathway proteins. Comparison of the two A. niger genomes for their gene sets show that many of these proteins may have essential pleiotropic functions next to mating and meiosis.
ISBN:	978-90-8686-065-4
Tárgyszavak:	Természettudományok Biológiai tudományok könyvfejezet könyvrészlet asexuality mating type genes meiosis related genes
Megjelenés:	Aspergillus in the genomic era / ed. by János Varga, Robert A. Samson. - p. 107-131. -
További szerzők:	Diepeningen, Anne D. van Varga János Debets, Alfons J. M. Hoekstra, Rolf F.
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001-es BibID:	BIBFORM108315
035-os BibID:	(Scopus)33846861493 (WOS)000244064000028
Első szerző:	Pel, Herman J.
Cím:	Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88 / Herman J. Pel, Johannes H. de Winde, David B. Archer, Paul S. Dyer, Gerald Hofmann, Peter J. Schaap, Geoffrey Turner, Ronald P. de Vries, Richard Albang, Kaj Albermann, Mikael R. Andersen, Jannick D. Bendtsen, Jacques A. E. Benen, Marco van den Berg, Stefaan Breestraat, Mark X. Caddick, Roland Contreras, Michael Cornell, Pedro M. Coutinho, Etienne G. J. Danchin, Alfons J. M. Debets, Peter Dekker, Piet W. M. van Dijck, Alard van Dijk, Lubbert Dijkhuizen, Arnold J. M. Driessen, Christophe d'Enfert, Steven Geysens, Coenie Goosen, Gert S. P. Groot, Piet W. J. de Groot, Thomas Guillemette, Bernard Henrissat, Marga Herweijer, Johannes P. T. W. van den Hombergh, Cees A. M. J. J. van den Hondel, Rene T. J. M. van der Heijden, Rachel M. van der Kaaij, Frans M. Klis, Harrie J. Kools, Christian P. Kubicek, Patricia A. van Kuyk, Jürgen Lauber, Xin Lu, Marc J. E. C. van der Maarel, Rogier Meulenberg, Hildegard Menke, Martin A. Mortimer, Jens Nielsen, Stephen G. Oliver, Maurien Olsthoorn, Karoly Pal, Noël N. M. E. van Peij, Arthur F. J. Ram, Ursula Rinas, Johannes A. Roubos, Cees M. J. Sagt, Monika Schmoll, Jibin Sun, David Ussery, Janos Varga, Wouter Vervecken, Peter J. J. van de Vondervoort, Holger Wedler, Han A. B. Wösten, An-Ping Zeng, Albert J. J. van Ooyen, Jaap Visser, Hein Stam
Dátum:	2007
ISSN:	1087-0156
Megjegyzések:	The filamentous fungus Aspergillus niger is widely exploited by the fermentation industry for the production of enzymes and organic acids, particularly citric acid. We sequenced the 33.9-megabase genome of A. niger CBS 513.88, the ancestor of currently used enzyme production strains. A high level of synteny was observed with other aspergilli sequenced. Strong function predictions were made for 6,506 of the 14,165 open reading frames identified. A detailed description of the components of the protein secretion pathway was made and striking differences in the hydrolytic enzyme spectra of aspergilli were observed. A reconstructed metabolic network comprising 1,069 unique reactions illustrates the versatile metabolism of A. niger. Noteworthy is the large number of major facilitator superfamily transporters and fungal zinc binuclear cluster transcription factors, and the presence of putative gene clusters for fumonisin and ochratoxin A synthesis.
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Nature Biotechnology. - 25 : 2 (2007), p. 221-231. -
További szerzők:	Winde, Johannes H. de Archer, David Dyer, Paul S. Hofmann, Gerald Schaap, Peter J. Turner, Geoffrey De Vries, Ronald P. Albang, Richard Albermann, Kaj Andersen, Mikael R. Bendtsen, Jannick D. Benen, Jacques A. E. Berg, Marco van den Breestraat, Stefaan Caddick, Mark X. Contreras, Roland Cornell, Michael J. Coutinho, Pedro M. Danchin, Etienne G. J. Debets, Alfons J. M. Dekker, Peter Dijck, Piet W. M. van Dijk, Alard van Dijkhuizen, Lubbert Driessen, Arnold J. M. d'Enfert, Christophe Geysens, Steven Goosen, Coenie Groot, Gert S. P. Groot, Piet W. J. de Guillemette, Thomas Henrissat, Bernard Herweijer, Marga Hombergh, Johannes P. T. W. van den Hondel, Cees A. M. J. J. van den Heijden, Rene T. J. M. van der Kaaij, Rachel M. van der Klis, Frans M. Kools, Harrie J. Kubicek, Christian P. Kuyk, Patricia A. van Lauber, Jürgen Lu, Xin Maarel, Marc J. E. C. van der Meulenberg, Rogier Menke, Hildegard Mortimer, Martin A. Nielsen, Jens Oliver, Stephen G. Olsthoorn, Maurien Pál Károly (1978-) (mikrobiológus) Peij, Noël N. M. E. van Ram, Arthur F.J. Rinas, Ursula Roubos, Johannes A. Sagt, Cees M. J. Schmoll, Monika Sun, Jibin Ussery, Dave Varga János Vervecken, Wouter Vondervoort, Peter J. I. van de Wedler, Holger Wösten, Han A. B. Zeng, An Ping Ooyen, Albert J. J. van Visser, Jaap Stam, Hein
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001-es BibID:	BIBFORM117562
Első szerző:	Varga János
Cím:	Evolutionary Relationships among Economically Important Species of Aspergillus Subgenera Aspergillus and Fumigati / János Varga, Krisztina Rigó, Sándor Kocsubé, Károly Pál, Beáta Tóth, Robert A. Samson, Zotia Kozaki Ewicz
Dátum:	2006
Megjegyzések:	The genus Aspergillus is one of the most important filamentous fungal genera. Aspergillus species are used for the production of several enzymes, drugs and other metabolites useful for mankind. On the other hand, Aspergillus species produce a range of mycotoxins harmful to humans and animals, and can also cause several human and animal diseases. Molecular techniques enabled mycologists to get an insight into the phylogenetics of Aspergilli, and the evolution of mycotoxin production with special emphasis on aflatoxin biosynthesis. Phylogenetically unrelated species were found to produce the same mycotoxins. For example, aflatoxins have been produced under laboratory conditions by species belonging to three different sections, while ochratoxin A and patulin are produced by a variety of unrelated species. Based on this observation, mycotoxin-producing abilities of the isolates were lost (or gained) several times during the evolution of the genus. In this review, attempts have been made to summarize the current knowledge on the taxonomy of economically important Aspergilli belonging to Aspergillus subgenera Aspergillus and Fumigati, and on the evolution of mycotoxin production.
ISBN:	9781578084135
Tárgyszavak:	Természettudományok Biológiai tudományok könyvfejezet könyvrészlet Aflatoxin Eurotium Neosartorya Petromyces ochratoxin phylogenetics taxonomy
Megjelenés:	Plant Genome: Biodiversity and EvolutionVol. 2, Part B Lower Groups / eds. Arun Kumar Sharma, Archana Sharma. - p. 285-332. -
További szerzők:	Rigó Krisztina Kocsubé Sándor Pál Károly (1978-) (mikrobiológus) Tóth Beáta Samson, Robert A. Kozaki Ewicz, Zotia
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