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001-es BibID:BIBFORM118839
035-os BibID:(cikkazonosító)4387 (Scopus)85185693265
Első szerző:Lugata, James Kachungwa (Ph.D hallgató)
Cím:In ovo feeding of methionine affects antioxidant status and growth-related gene expression of TETRA SL and Hungarian indigenous chicks / James K. Lugata, Sawadi F. Ndunguru, Gebrehaweria K. Reda, Gabriella Gulyás, Renáta Knop, János Oláh, Levente Czeglédi, Csaba Szabó
Dátum:2024
ISSN:2045-2322
Megjegyzések:Methionine (Met) plays a substantial role in poultry due to its involvement in several pathways, including enhancing antioxidant status and improving growth performance and health status. This study examined how in ovo feeding of Met affects hatching performance, antioxidant status, and hepatic gene expression related to growth and immunity in the TETRA-SL LL hybrid (TSL) commercial layer and Hungarian partridge colored hen (HPC) indigenous genotypes. The eggs were injected with saline, DL-Met, and L-Met on 17.5 days of embryonic development. The results showed that the in ovo feeding of DL-Met significantly increased the hatching weight and ferric reducing the ability of the plasma (FRAP) compared with L-Met. The in ovo feeding of either Met source enhanced the liver health and function and hepatic antioxidant status of the chicks. The genotype`s differences were significant; the TSL genotype had better hatching weight, an antioxidant defense system, and downregulated growth-related gene expression than the HPC genotype. In ovo feeding of either Met source enhanced the chicks' health status and antioxidant status, and DL-Met improved the hatching weight of the chicks more than L-Met. Genotype differences were significantly evident in the responses of growth performance, antioxidant status, blood biochemical parameters, and gene expression to Met sources.
Tárgyszavak:Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Scientific Reports. - 14 : 1 (2024), p. 1-14. -
További szerzők:Ndunguru, Sawadi Fransisco (1980-) Reda, Gebrehaweria Kidane (Phd hallgató) Gulyás Gabriella (1985-) (agrár) Knop Renáta (1983-) (állatorvos) Oláh János (1976-) (állattenyésztés) Czeglédi Levente (1977-) (agrármérnök) Szabó Csaba (1968-) (agrármérnök)
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001-es BibID:BIBFORM120370
Első szerző:Reda, Gebrehaweria Kidane (Phd hallgató)
Cím:Dietary restriction reveals sex-specifc expression of the mTOR pathway genes in Japanese quails / Gebrehaweria K. Reda, Sawadi F. Ndunguru, Brigitta Csernus, Renáta Knop, James K. Lugata, Csaba Szabó, Levente Czeglédi, Ádám Z. Lendvai
Dátum:2024
ISSN:2045-2322
Megjegyzések:Limited resources affect an organism's physiology through the conserved metabolic pathway, the mechanistic target of rapamycin (mTOR). Males and females often react differently to nutritional limitation, but whether it leads to differential mTOR pathway expression remains unknown. Recently, we found that dietary restriction (DR) induced significant changes in the expression of mTOR pathway genes in female Japanese quails (Coturnix japonica). We simultaneously exposed 32 male and female Japanese quails to either 20%, 30%, 40% restriction or ad libitum feeding for 14 days and determined the expression of six key genes of the mTOR pathway in the liver to investigate sex differences in the expression patterns. We found that DR significantly reduced body mass, albeit the effect was milder in males compared to females. We observed sex-specific liver gene expression. DR downregulated mTOR expression more in females than in males. Under moderate DR, ATG9A and RPS6K1 expressions were increased more in males than in females. Like females, body mass in males was correlated positively with mTOR and IGF1, but negatively with ATG9A and RS6K1 expressions. Our findings highlight that sexes may cope with nutritional deficits differently and emphasise the importance of considering sexual differences in studies of dietary restriction.
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Scientific Reports. - 14 : 1 (2024), p. 1-14. -
További szerzők:Ndunguru, Sawadi Fransisco (1980-) Csernus Brigitta (1991-) (élelmiszerbiztonsági és -minőségi mérnök) Knop Renáta (1983-) (állatorvos) Lugata, James Kachungwa (1992-) (Ph.D hallgató) Szabó Csaba (1968-) (agrármérnök) Czeglédi Levente (1977-) (agrármérnök) Lendvai Ádám Zoltán (1977-) (biológus)
Pályázati támogatás:K139021
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Intézményi repozitóriumban (DEA) tárolt változat
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